Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015674964> ?p ?o ?g. }
Showing items 1 to 97 of
97
with 100 items per page.
- W2015674964 endingPage "22" @default.
- W2015674964 startingPage "13" @default.
- W2015674964 abstract "Background. Systemic antibiotics are routinely prescribed for severe acute malnutrition (SAM). However, there is no consensus regarding the most suitable regimen. In a therapeutic feeding centre in Khartoum, Sudan, a randomised, unblinded, superiority-controlled trial was conducted, comparing once daily intramuscular injection with ceftriaxone for 2 days with oral amoxicillin twice daily for 5 days in children aged 6–59 months with SAM. Methods. Commencing with the first measured weight gain (WG) following admission, the risk difference and 95% confidence interval (95% CI) for children with a WG ≥ 10 g/kg/day were calculated over a 14-day period. The recovery rate and case fatality ratio (CFR) between the two groups were also calculated. Results. In an intention-to-treat analysis of 458 children, 53.5% (123/230) in the amoxicillin group and 55.7% (127/228, difference 2.2%, 95% CI −6.9–11.3) in the ceftriaxone group had a WG ≥ 10 g/kg/day during a 14-day period. Recovery rate was 70% (161/230) in the amoxicillin group and 74.6% (170/228) in the ceftriaxone group (p=0.27). CFR was 3.9% (9/230) and 3.1% (7/228), respectively (p=0.67). Most deaths occurred within the 1st 2 weeks of admission. Conclusion. In the absence of severe complications, either ceftriaxone or amoxicillin is appropriate for malnourished children. However, in ambulatory programmes, especially where there are large numbers of admissions, ceftriaxone should facilitate the work of medical personnel." @default.
- W2015674964 created "2016-06-24" @default.
- W2015674964 creator A5001084754 @default.
- W2015674964 creator A5002458341 @default.
- W2015674964 creator A5015148984 @default.
- W2015674964 creator A5037482092 @default.
- W2015674964 creator A5044971903 @default.
- W2015674964 creator A5048608901 @default.
- W2015674964 creator A5067893065 @default.
- W2015674964 creator A5072163541 @default.
- W2015674964 creator A5073376552 @default.
- W2015674964 date "2008-03-01" @default.
- W2015674964 modified "2023-10-17" @default.
- W2015674964 title "Treatment of severe malnutrition with 2-day intramuscular ceftriaxone<i>vs</i>5-day amoxicillin" @default.
- W2015674964 cites W1775066897 @default.
- W2015674964 cites W1968465987 @default.
- W2015674964 cites W1971259194 @default.
- W2015674964 cites W2003183801 @default.
- W2015674964 cites W2005299041 @default.
- W2015674964 cites W2010535995 @default.
- W2015674964 cites W2027495005 @default.
- W2015674964 cites W2037350638 @default.
- W2015674964 cites W2056949610 @default.
- W2015674964 cites W2097288692 @default.
- W2015674964 cites W2130968135 @default.
- W2015674964 cites W2138534370 @default.
- W2015674964 doi "https://doi.org/10.1179/146532808x270635" @default.
- W2015674964 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/18318945" @default.
- W2015674964 hasPublicationYear "2008" @default.
- W2015674964 type Work @default.
- W2015674964 sameAs 2015674964 @default.
- W2015674964 citedByCount "18" @default.
- W2015674964 countsByYear W20156749642012 @default.
- W2015674964 countsByYear W20156749642013 @default.
- W2015674964 countsByYear W20156749642018 @default.
- W2015674964 countsByYear W20156749642019 @default.
- W2015674964 countsByYear W20156749642020 @default.
- W2015674964 countsByYear W20156749642021 @default.
- W2015674964 countsByYear W20156749642022 @default.
- W2015674964 crossrefType "journal-article" @default.
- W2015674964 hasAuthorship W2015674964A5001084754 @default.
- W2015674964 hasAuthorship W2015674964A5002458341 @default.
- W2015674964 hasAuthorship W2015674964A5015148984 @default.
- W2015674964 hasAuthorship W2015674964A5037482092 @default.
- W2015674964 hasAuthorship W2015674964A5044971903 @default.
- W2015674964 hasAuthorship W2015674964A5048608901 @default.
- W2015674964 hasAuthorship W2015674964A5067893065 @default.
- W2015674964 hasAuthorship W2015674964A5072163541 @default.
- W2015674964 hasAuthorship W2015674964A5073376552 @default.
- W2015674964 hasConcept C126322002 @default.
- W2015674964 hasConcept C141071460 @default.
- W2015674964 hasConcept C187212893 @default.
- W2015674964 hasConcept C2776520383 @default.
- W2015674964 hasConcept C2779708577 @default.
- W2015674964 hasConcept C2781413609 @default.
- W2015674964 hasConcept C35785553 @default.
- W2015674964 hasConcept C42219234 @default.
- W2015674964 hasConcept C44249647 @default.
- W2015674964 hasConcept C501593827 @default.
- W2015674964 hasConcept C71924100 @default.
- W2015674964 hasConcept C86803240 @default.
- W2015674964 hasConcept C89423630 @default.
- W2015674964 hasConceptScore W2015674964C126322002 @default.
- W2015674964 hasConceptScore W2015674964C141071460 @default.
- W2015674964 hasConceptScore W2015674964C187212893 @default.
- W2015674964 hasConceptScore W2015674964C2776520383 @default.
- W2015674964 hasConceptScore W2015674964C2779708577 @default.
- W2015674964 hasConceptScore W2015674964C2781413609 @default.
- W2015674964 hasConceptScore W2015674964C35785553 @default.
- W2015674964 hasConceptScore W2015674964C42219234 @default.
- W2015674964 hasConceptScore W2015674964C44249647 @default.
- W2015674964 hasConceptScore W2015674964C501593827 @default.
- W2015674964 hasConceptScore W2015674964C71924100 @default.
- W2015674964 hasConceptScore W2015674964C86803240 @default.
- W2015674964 hasConceptScore W2015674964C89423630 @default.
- W2015674964 hasIssue "1" @default.
- W2015674964 hasLocation W20156749641 @default.
- W2015674964 hasLocation W20156749642 @default.
- W2015674964 hasOpenAccess W2015674964 @default.
- W2015674964 hasPrimaryLocation W20156749641 @default.
- W2015674964 hasRelatedWork W2050901295 @default.
- W2015674964 hasRelatedWork W2597206478 @default.
- W2015674964 hasRelatedWork W2898523618 @default.
- W2015674964 hasRelatedWork W3027837924 @default.
- W2015674964 hasRelatedWork W3154667568 @default.
- W2015674964 hasRelatedWork W3175392830 @default.
- W2015674964 hasRelatedWork W3211243023 @default.
- W2015674964 hasRelatedWork W4232182398 @default.
- W2015674964 hasRelatedWork W4313946030 @default.
- W2015674964 hasRelatedWork W4385069636 @default.
- W2015674964 hasVolume "28" @default.
- W2015674964 isParatext "false" @default.
- W2015674964 isRetracted "false" @default.
- W2015674964 magId "2015674964" @default.
- W2015674964 workType "article" @default.