Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015679993> ?p ?o ?g. }
- W2015679993 endingPage "61" @default.
- W2015679993 startingPage "61" @default.
- W2015679993 abstract "Members of the genus Nocardia are ubiquitous environmental saprophytes capable to cause human pulmonary, disseminated and cutaneous nocardiosis or bovine mastitis. Innate immunity appears to play an important role in early defense against Nocardia species. To elucidate the contribution of antimicrobial peptides (AMPs) in innate defense against Nocardia, the activity of human α-defensins human neutrophil peptides (HNPs) 1-3, human β-defensin (hBD)-3 and cathelicidin LL-37 as well as bovine β-defensins lingual and tracheal antimicrobial peptides (LAP, TAP) and bovine neutrophil-derived indolicidin against four important Nocardia species was investigated. Whereas N. farcinica ATCC 3318 and N. nova ATCC 33726 were found to be susceptible to all investigated human and bovine AMPs, N. asteroides ATCC 19247 was killed exclusively by neutrophil-derived human α-defensins HNP 1-3 and bovine indolicidin. N. brasiliensis ATCC 19296 was found to exhibit complete resistance to investigated human AMPs and to be susceptible only to bovine indolicidin. Selected AMPs are capable to contribute to the first line of defense against Nocardia, yet, susceptibility appears to vary across different Nocardia species. Obtained results of neutrophil-derived AMPs to possess the broadest antinocardial spectrum are remarkable, since nocardiosis is characterized by a neutrophil-rich infiltrate in vivo." @default.
- W2015679993 created "2016-06-24" @default.
- W2015679993 creator A5007311270 @default.
- W2015679993 creator A5017457858 @default.
- W2015679993 creator A5039047497 @default.
- W2015679993 creator A5051194952 @default.
- W2015679993 creator A5053302760 @default.
- W2015679993 creator A5073736169 @default.
- W2015679993 creator A5073851794 @default.
- W2015679993 date "2010-01-01" @default.
- W2015679993 modified "2023-10-18" @default.
- W2015679993 title "Differential activity of innate defense antimicrobial peptides against Nocardia species" @default.
- W2015679993 cites W1556677948 @default.
- W2015679993 cites W1580428881 @default.
- W2015679993 cites W1814215520 @default.
- W2015679993 cites W1910498995 @default.
- W2015679993 cites W1913694818 @default.
- W2015679993 cites W1931276869 @default.
- W2015679993 cites W1943160106 @default.
- W2015679993 cites W1969465403 @default.
- W2015679993 cites W1979192175 @default.
- W2015679993 cites W1993355081 @default.
- W2015679993 cites W2014262351 @default.
- W2015679993 cites W2020137152 @default.
- W2015679993 cites W2022998979 @default.
- W2015679993 cites W2035158221 @default.
- W2015679993 cites W2054602599 @default.
- W2015679993 cites W2054758910 @default.
- W2015679993 cites W2065067981 @default.
- W2015679993 cites W2072247634 @default.
- W2015679993 cites W2084267501 @default.
- W2015679993 cites W2090042814 @default.
- W2015679993 cites W2097723879 @default.
- W2015679993 cites W2099612067 @default.
- W2015679993 cites W2108140555 @default.
- W2015679993 cites W2126734687 @default.
- W2015679993 cites W2127231514 @default.
- W2015679993 cites W2129706499 @default.
- W2015679993 cites W2131192673 @default.
- W2015679993 cites W2131735123 @default.
- W2015679993 cites W2140472579 @default.
- W2015679993 cites W2147489483 @default.
- W2015679993 cites W2165412330 @default.
- W2015679993 cites W2169759699 @default.
- W2015679993 doi "https://doi.org/10.1186/1471-2180-10-61" @default.
- W2015679993 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2834671" @default.
- W2015679993 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20178618" @default.
- W2015679993 hasPublicationYear "2010" @default.
- W2015679993 type Work @default.
- W2015679993 sameAs 2015679993 @default.
- W2015679993 citedByCount "17" @default.
- W2015679993 countsByYear W20156799932012 @default.
- W2015679993 countsByYear W20156799932015 @default.
- W2015679993 countsByYear W20156799932016 @default.
- W2015679993 countsByYear W20156799932017 @default.
- W2015679993 countsByYear W20156799932018 @default.
- W2015679993 countsByYear W20156799932019 @default.
- W2015679993 countsByYear W20156799932020 @default.
- W2015679993 countsByYear W20156799932021 @default.
- W2015679993 countsByYear W20156799932023 @default.
- W2015679993 crossrefType "journal-article" @default.
- W2015679993 hasAuthorship W2015679993A5007311270 @default.
- W2015679993 hasAuthorship W2015679993A5017457858 @default.
- W2015679993 hasAuthorship W2015679993A5039047497 @default.
- W2015679993 hasAuthorship W2015679993A5051194952 @default.
- W2015679993 hasAuthorship W2015679993A5053302760 @default.
- W2015679993 hasAuthorship W2015679993A5073736169 @default.
- W2015679993 hasAuthorship W2015679993A5073851794 @default.
- W2015679993 hasBestOaLocation W20156799931 @default.
- W2015679993 hasConcept C136449434 @default.
- W2015679993 hasConcept C203014093 @default.
- W2015679993 hasConcept C24527192 @default.
- W2015679993 hasConcept C2776460866 @default.
- W2015679993 hasConcept C2776846390 @default.
- W2015679993 hasConcept C2777379352 @default.
- W2015679993 hasConcept C2779448432 @default.
- W2015679993 hasConcept C4937899 @default.
- W2015679993 hasConcept C523546767 @default.
- W2015679993 hasConcept C540938839 @default.
- W2015679993 hasConcept C54355233 @default.
- W2015679993 hasConcept C86803240 @default.
- W2015679993 hasConcept C8891405 @default.
- W2015679993 hasConcept C89423630 @default.
- W2015679993 hasConceptScore W2015679993C136449434 @default.
- W2015679993 hasConceptScore W2015679993C203014093 @default.
- W2015679993 hasConceptScore W2015679993C24527192 @default.
- W2015679993 hasConceptScore W2015679993C2776460866 @default.
- W2015679993 hasConceptScore W2015679993C2776846390 @default.
- W2015679993 hasConceptScore W2015679993C2777379352 @default.
- W2015679993 hasConceptScore W2015679993C2779448432 @default.
- W2015679993 hasConceptScore W2015679993C4937899 @default.
- W2015679993 hasConceptScore W2015679993C523546767 @default.
- W2015679993 hasConceptScore W2015679993C540938839 @default.
- W2015679993 hasConceptScore W2015679993C54355233 @default.
- W2015679993 hasConceptScore W2015679993C86803240 @default.
- W2015679993 hasConceptScore W2015679993C8891405 @default.
- W2015679993 hasConceptScore W2015679993C89423630 @default.
- W2015679993 hasIssue "1" @default.