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- W2015690816 abstract "Abstract The growth of nuclei into crystals requires a metastable solution phase with respect to the growing particles (supersaturation), and the presence of impurities. The rate of growth is proportional to the diameter of the particles, and is related to the surface to volume ratio of the crystal. Trace components can modify cyrstal habit and may be factors in determining the characteristics of bone mineral. Orientation of bone cystals parallel to the collagen fibers implies that the organic matrix acts as a habit modifier. The small size of bone hydroxyapatite crystals (640 A or less), in contrast to the synthetic hydroxyapatite crystals prepared in the laboratory (2 · 10 7 A or 2.0 mm), suggests that factors in vivo operate to limit their size. Cessation of crystal growth in a supersaturated solution is likely to be caused by surface adsorption of inhibiting ions or compounds. A mechanical barrier imposed by the collagen fibrils, and decreased renewal of the fluids surrounding the crystal may also be involved. The inorganic portion of mineralized tissues in two phases: a crystalline core of hydroxyapatite of [Ca 10 (PO 4 ) 6 (OH 2 )] and an adsorbed outer shell which is of an amorphous or gel-like nature, containing anions such as carbonate, citrate, fluorides, and cations such as Na, Mg, Pb, and Sr. This does not preclude entry of a few such ions into the lattice. The inorganic composition of bones and teeth depends on the composition of the surrounding fluids (which can be regulated by dietar constituents). For example, the CO 3 /PO 4 ratio of minerals in bone and teeth is related to the CO 3 /PO 4 ratio of blood serum." @default.
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- W2015690816 title "Crystal growth in mineralizing tissues" @default.
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- W2015690816 doi "https://doi.org/10.1016/0006-3002(60)90361-9" @default.
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