FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015728684> ?p ?o ?g. }

• W2015728684 endingPage "11103" @default.
• W2015728684 startingPage "11095" @default.
• W2015728684 abstract "The kinetics of decomposition of the pharmaceutical ranitidine (a major precursor of NDMA) during chloramination was investigated and some decomposition byproducts were identified by using high performance liquid chromatography coupled with mass spectrometry (HPLC-MS). The reaction between monochloramine and ranitidine followed second order kinetics and was acid-catalyzed. Decomposition of ranitidine formed different byproducts depending on the applied monochloramine concentration. Most identified products were chlorinated and hydroxylated analogues of ranitidine. In excess of monochloramine, nucleophilic substitution between ranitidine and monochloramine led to byproducts that are critical intermediates involved in the formation of NDMA, for example, a carbocation formed from the decomposition of the methylfuran moiety of ranitidine. A complete mechanism is proposed to explain the high formation yield of NDMA from chloramination of ranitidine. These results are of great importance to understand the formation of NDMA by chloramination of tertiary amines." @default.
• W2015728684 created "2016-06-24" @default.
• W2015728684 creator A5028116789 @default.
• W2015728684 creator A5039122125 @default.
• W2015728684 creator A5061331023 @default.
• W2015728684 creator A5072823408 @default.
• W2015728684 creator A5076510460 @default.
• W2015728684 date "2012-09-26" @default.
• W2015728684 modified "2023-10-17" @default.
• W2015728684 title "NDMA Formation by Chloramination of Ranitidine: Kinetics and Mechanism" @default.
• W2015728684 cites W1981380378 @default.
• W2015728684 cites W1982768495 @default.
• W2015728684 cites W1985242165 @default.
• W2015728684 cites W1989079106 @default.
• W2015728684 cites W2000369642 @default.
• W2015728684 cites W2002912509 @default.
• W2015728684 cites W2018284275 @default.
• W2015728684 cites W2019512261 @default.
• W2015728684 cites W2021621994 @default.
• W2015728684 cites W2021870414 @default.
• W2015728684 cites W2022002361 @default.
• W2015728684 cites W2030947599 @default.
• W2015728684 cites W2033626139 @default.
• W2015728684 cites W2035007027 @default.
• W2015728684 cites W2036245115 @default.
• W2015728684 cites W2037766564 @default.
• W2015728684 cites W2038992270 @default.
• W2015728684 cites W2049405839 @default.
• W2015728684 cites W2049833052 @default.
• W2015728684 cites W2058942354 @default.
• W2015728684 cites W2062808747 @default.
• W2015728684 cites W2079446688 @default.
• W2015728684 cites W2080990907 @default.
• W2015728684 cites W2086955386 @default.
• W2015728684 cites W2089948166 @default.
• W2015728684 cites W2090848785 @default.
• W2015728684 cites W2092266047 @default.
• W2015728684 cites W2145937475 @default.
• W2015728684 cites W2155812824 @default.
• W2015728684 cites W2156292926 @default.
• W2015728684 cites W2316936036 @default.
• W2015728684 cites W3137930922 @default.
• W2015728684 doi "https://doi.org/10.1021/es3023094" @default.
• W2015728684 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/22967139" @default.
• W2015728684 hasPublicationYear "2012" @default.
• W2015728684 type Work @default.
• W2015728684 sameAs 2015728684 @default.
• W2015728684 citedByCount "103" @default.
• W2015728684 countsByYear W20157286842012 @default.
• W2015728684 countsByYear W20157286842013 @default.
• W2015728684 countsByYear W20157286842014 @default.
• W2015728684 countsByYear W20157286842015 @default.
• W2015728684 countsByYear W20157286842016 @default.
• W2015728684 countsByYear W20157286842017 @default.
• W2015728684 countsByYear W20157286842018 @default.
• W2015728684 countsByYear W20157286842019 @default.
• W2015728684 countsByYear W20157286842020 @default.
• W2015728684 countsByYear W20157286842021 @default.
• W2015728684 countsByYear W20157286842022 @default.
• W2015728684 countsByYear W20157286842023 @default.
• W2015728684 crossrefType "journal-article" @default.
• W2015728684 hasAuthorship W2015728684A5028116789 @default.
• W2015728684 hasAuthorship W2015728684A5039122125 @default.
• W2015728684 hasAuthorship W2015728684A5061331023 @default.
• W2015728684 hasAuthorship W2015728684A5072823408 @default.
• W2015728684 hasAuthorship W2015728684A5076510460 @default.
• W2015728684 hasBestOaLocation W20157286842 @default.
• W2015728684 hasConcept C121332964 @default.
• W2015728684 hasConcept C124681953 @default.
• W2015728684 hasConcept C148898269 @default.
• W2015728684 hasConcept C155647269 @default.
• W2015728684 hasConcept C161790260 @default.
• W2015728684 hasConcept C178790620 @default.
• W2015728684 hasConcept C185592680 @default.
• W2015728684 hasConcept C192937433 @default.
• W2015728684 hasConcept C2776849215 @default.
• W2015728684 hasConcept C2777445857 @default.
• W2015728684 hasConcept C2779293432 @default.
• W2015728684 hasConcept C2779488458 @default.
• W2015728684 hasConcept C43617362 @default.
• W2015728684 hasConcept C505241676 @default.
• W2015728684 hasConcept C62520636 @default.
• W2015728684 hasConcept C71924100 @default.
• W2015728684 hasConcept C94412978 @default.
• W2015728684 hasConcept C98274493 @default.
• W2015728684 hasConceptScore W2015728684C121332964 @default.
• W2015728684 hasConceptScore W2015728684C124681953 @default.
• W2015728684 hasConceptScore W2015728684C148898269 @default.
• W2015728684 hasConceptScore W2015728684C155647269 @default.
• W2015728684 hasConceptScore W2015728684C161790260 @default.
• W2015728684 hasConceptScore W2015728684C178790620 @default.
• W2015728684 hasConceptScore W2015728684C185592680 @default.
• W2015728684 hasConceptScore W2015728684C192937433 @default.
• W2015728684 hasConceptScore W2015728684C2776849215 @default.
• W2015728684 hasConceptScore W2015728684C2777445857 @default.
• W2015728684 hasConceptScore W2015728684C2779293432 @default.
• W2015728684 hasConceptScore W2015728684C2779488458 @default.
• W2015728684 hasConceptScore W2015728684C43617362 @default.

• next