Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015742029> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2015742029 endingPage "530" @default.
- W2015742029 startingPage "525" @default.
- W2015742029 abstract "Trimethyltin is an organotin compound that produces marked neurotoxicity in both adult and developing animals. The limbic system is a primary CNS target site for this toxicity, and a prominent behavioral effect of TMT is disruption of learning and memory. Impairment of cognitive development has also been suggested by studies showing that rats neonatally exposed to TMT cannot perform spatial working memory tasks during adulthood. However, the question of how early in ontogeny such deficits can be detected has not been addressed. The present study examined this question with a T-maze delayed alternation learning paradigm. Long-Evans rat pups, injected IP on Postnatal Day 10 (PND 10) with 6 mg/kg TMT and tested on PND 18, were unable to learn delayed alternation in the manner shown by vehicle control pups. However, TMT- and vehicle-treated groups were both able to learn a simple position discrimination. These findings indicate a selective impairment of spatial working memory by neonatal TMT exposure and show that this impairment can be demonstrated during the preweanling period in the rat." @default.
- W2015742029 created "2016-06-24" @default.
- W2015742029 creator A5014616818 @default.
- W2015742029 creator A5065164867 @default.
- W2015742029 creator A5076962952 @default.
- W2015742029 date "1991-09-01" @default.
- W2015742029 modified "2023-10-11" @default.
- W2015742029 title "Neonatal exposure to trimethyltin disrupts spatial delayed alternation learning in preweanling rats" @default.
- W2015742029 cites W1969246069 @default.
- W2015742029 cites W1993706536 @default.
- W2015742029 cites W2006144341 @default.
- W2015742029 cites W2033319161 @default.
- W2015742029 cites W2040496275 @default.
- W2015742029 cites W2042557213 @default.
- W2015742029 cites W2062247033 @default.
- W2015742029 cites W2073090308 @default.
- W2015742029 cites W2124633773 @default.
- W2015742029 cites W4234550249 @default.
- W2015742029 cites W4255203618 @default.
- W2015742029 doi "https://doi.org/10.1016/0892-0362(91)90060-a" @default.
- W2015742029 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/1758406" @default.
- W2015742029 hasPublicationYear "1991" @default.
- W2015742029 type Work @default.
- W2015742029 sameAs 2015742029 @default.
- W2015742029 citedByCount "31" @default.
- W2015742029 countsByYear W20157420292012 @default.
- W2015742029 countsByYear W20157420292013 @default.
- W2015742029 countsByYear W20157420292014 @default.
- W2015742029 countsByYear W20157420292015 @default.
- W2015742029 countsByYear W20157420292016 @default.
- W2015742029 countsByYear W20157420292017 @default.
- W2015742029 countsByYear W20157420292018 @default.
- W2015742029 countsByYear W20157420292020 @default.
- W2015742029 crossrefType "journal-article" @default.
- W2015742029 hasAuthorship W2015742029A5014616818 @default.
- W2015742029 hasAuthorship W2015742029A5065164867 @default.
- W2015742029 hasAuthorship W2015742029A5076962952 @default.
- W2015742029 hasConcept C126322002 @default.
- W2015742029 hasConcept C134018914 @default.
- W2015742029 hasConcept C138496976 @default.
- W2015742029 hasConcept C138885662 @default.
- W2015742029 hasConcept C15744967 @default.
- W2015742029 hasConcept C169760540 @default.
- W2015742029 hasConcept C169900460 @default.
- W2015742029 hasConcept C26826806 @default.
- W2015742029 hasConcept C2775847253 @default.
- W2015742029 hasConcept C2779491297 @default.
- W2015742029 hasConcept C2781161787 @default.
- W2015742029 hasConcept C29730261 @default.
- W2015742029 hasConcept C2985665543 @default.
- W2015742029 hasConcept C37291498 @default.
- W2015742029 hasConcept C41895202 @default.
- W2015742029 hasConcept C42407357 @default.
- W2015742029 hasConcept C44752575 @default.
- W2015742029 hasConcept C71924100 @default.
- W2015742029 hasConceptScore W2015742029C126322002 @default.
- W2015742029 hasConceptScore W2015742029C134018914 @default.
- W2015742029 hasConceptScore W2015742029C138496976 @default.
- W2015742029 hasConceptScore W2015742029C138885662 @default.
- W2015742029 hasConceptScore W2015742029C15744967 @default.
- W2015742029 hasConceptScore W2015742029C169760540 @default.
- W2015742029 hasConceptScore W2015742029C169900460 @default.
- W2015742029 hasConceptScore W2015742029C26826806 @default.
- W2015742029 hasConceptScore W2015742029C2775847253 @default.
- W2015742029 hasConceptScore W2015742029C2779491297 @default.
- W2015742029 hasConceptScore W2015742029C2781161787 @default.
- W2015742029 hasConceptScore W2015742029C29730261 @default.
- W2015742029 hasConceptScore W2015742029C2985665543 @default.
- W2015742029 hasConceptScore W2015742029C37291498 @default.
- W2015742029 hasConceptScore W2015742029C41895202 @default.
- W2015742029 hasConceptScore W2015742029C42407357 @default.
- W2015742029 hasConceptScore W2015742029C44752575 @default.
- W2015742029 hasConceptScore W2015742029C71924100 @default.
- W2015742029 hasIssue "5" @default.
- W2015742029 hasLocation W20157420291 @default.
- W2015742029 hasLocation W20157420292 @default.
- W2015742029 hasOpenAccess W2015742029 @default.
- W2015742029 hasPrimaryLocation W20157420291 @default.
- W2015742029 hasRelatedWork W1978884049 @default.
- W2015742029 hasRelatedWork W2010506153 @default.
- W2015742029 hasRelatedWork W203247574 @default.
- W2015742029 hasRelatedWork W2048460159 @default.
- W2015742029 hasRelatedWork W2074870792 @default.
- W2015742029 hasRelatedWork W2131272770 @default.
- W2015742029 hasRelatedWork W2333773140 @default.
- W2015742029 hasRelatedWork W2347144788 @default.
- W2015742029 hasRelatedWork W4235297504 @default.
- W2015742029 hasRelatedWork W4386518398 @default.
- W2015742029 hasVolume "13" @default.
- W2015742029 isParatext "false" @default.
- W2015742029 isRetracted "false" @default.
- W2015742029 magId "2015742029" @default.
- W2015742029 workType "article" @default.