FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015757617> ?p ?o ?g. }

• W2015757617 endingPage "25" @default.
• W2015757617 startingPage "18" @default.
• W2015757617 abstract "Background. Liver transplantation (LTX) recipients with renal dysfunction may benefit from mycophenolate mofetil (MMF) and reduction or discontinuation of nephrotoxic calcineurin inhibitors (CNI). The authors report the first randomized, multicenter pilot studies of this approach (one study for patients on cyclosporine [CsA] and one for those on tacrolimus [Tac]). Methods. Patients 3 to 27 months post-LTX with greater than 20% reduced renal function since LTX, and creatinine 1.8 to 4.0 mg/dL, creatinine clearance 20 to 60 mL/min, or both, were randomized to discontinuation (group 1) or 50% reduction (group 2) of CNI dose, together with MMF 1.5 g administered twice daily and prednisone. Endpoints included measured glomerular filtration rate (GFR) 52 weeks after study entry and biopsy-proven rejection. Results. In the CsA and Tac trials, 15 and 12 patients, respectively, completed the 52-week follow-up. In the CsA trial, the mean GFR at baseline and week 52 were 35.0 and 57.8 mL/min (>15% improvement, five of six; unchanged, one of six) for group 1 and 46.0 and 63.8 mL/min (>15% improvement, four of nine; unchanged, three of nine; >15% deterioration, two of nine) for group 2. In the Tac trial, GFRs were 55.4 and 56.0 mL/min (>15% improvement, two of five; unchanged, three of five) for group 1 and 46.7 and 60.2 mL/min (>15% improvement, four of seven; unchanged, three of seven) for group 2. Mild or moderate rejection occurred in 38% and 9% of patients in groups 1 and 2 of the CsA trial and in 14% of each group of the patients in the Tac trial. Conclusions. These pilot studies show that in LTX recipients with renal dysfunction, MMF allows CNI dose reduction or discontinuation, improving or stabilizing GFR in most patients." @default.
• W2015757617 created "2016-06-24" @default.
• W2015757617 creator A5007647741 @default.
• W2015757617 creator A5018470542 @default.
• W2015757617 creator A5044231989 @default.
• W2015757617 date "2005-07-15" @default.
• W2015757617 modified "2023-10-15" @default.
• W2015757617 title "Mycophenolate Mofetil for Renal Dysfunction in Liver Transplant Recipients on Cyclosporine or Tacrolimus: Randomized, Prospective, Multicenter Pilot Study Results" @default.
• W2015757617 cites W141198166 @default.
• W2015757617 cites W1981713220 @default.
• W2015757617 cites W1989513872 @default.
• W2015757617 cites W2013299549 @default.
• W2015757617 cites W2020128905 @default.
• W2015757617 cites W2034762297 @default.
• W2015757617 cites W2034784814 @default.
• W2015757617 cites W2034953095 @default.
• W2015757617 cites W2040835239 @default.
• W2015757617 cites W2049191601 @default.
• W2015757617 cites W2055598277 @default.
• W2015757617 cites W2056054156 @default.
• W2015757617 cites W2060936723 @default.
• W2015757617 cites W2062278320 @default.
• W2015757617 cites W2090959382 @default.
• W2015757617 cites W2134672034 @default.
• W2015757617 cites W2152627520 @default.
• W2015757617 cites W2163721979 @default.
• W2015757617 cites W2168638212 @default.
• W2015757617 doi "https://doi.org/10.1097/01.tp.0000165118.00988.d7" @default.
• W2015757617 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/16003228" @default.
• W2015757617 hasPublicationYear "2005" @default.
• W2015757617 type Work @default.
• W2015757617 sameAs 2015757617 @default.
• W2015757617 citedByCount "88" @default.
• W2015757617 countsByYear W20157576172012 @default.
• W2015757617 countsByYear W20157576172013 @default.
• W2015757617 countsByYear W20157576172014 @default.
• W2015757617 countsByYear W20157576172015 @default.
• W2015757617 countsByYear W20157576172016 @default.
• W2015757617 countsByYear W20157576172017 @default.
• W2015757617 countsByYear W20157576172018 @default.
• W2015757617 countsByYear W20157576172019 @default.
• W2015757617 countsByYear W20157576172020 @default.
• W2015757617 countsByYear W20157576172021 @default.
• W2015757617 countsByYear W20157576172022 @default.
• W2015757617 crossrefType "journal-article" @default.
• W2015757617 hasAuthorship W2015757617A5007647741 @default.
• W2015757617 hasAuthorship W2015757617A5018470542 @default.
• W2015757617 hasAuthorship W2015757617A5044231989 @default.
• W2015757617 hasBestOaLocation W20157576171 @default.
• W2015757617 hasConcept C126189478 @default.
• W2015757617 hasConcept C126322002 @default.
• W2015757617 hasConcept C126894567 @default.
• W2015757617 hasConcept C128057223 @default.
• W2015757617 hasConcept C141071460 @default.
• W2015757617 hasConcept C159641895 @default.
• W2015757617 hasConcept C168563851 @default.
• W2015757617 hasConcept C204243189 @default.
• W2015757617 hasConcept C2778033501 @default.
• W2015757617 hasConcept C2778715236 @default.
• W2015757617 hasConcept C2779609443 @default.
• W2015757617 hasConcept C2780091579 @default.
• W2015757617 hasConcept C2780306776 @default.
• W2015757617 hasConcept C2909675724 @default.
• W2015757617 hasConcept C2911091166 @default.
• W2015757617 hasConcept C71924100 @default.
• W2015757617 hasConcept C90924648 @default.
• W2015757617 hasConceptScore W2015757617C126189478 @default.
• W2015757617 hasConceptScore W2015757617C126322002 @default.
• W2015757617 hasConceptScore W2015757617C126894567 @default.
• W2015757617 hasConceptScore W2015757617C128057223 @default.
• W2015757617 hasConceptScore W2015757617C141071460 @default.
• W2015757617 hasConceptScore W2015757617C159641895 @default.
• W2015757617 hasConceptScore W2015757617C168563851 @default.
• W2015757617 hasConceptScore W2015757617C204243189 @default.
• W2015757617 hasConceptScore W2015757617C2778033501 @default.
• W2015757617 hasConceptScore W2015757617C2778715236 @default.
• W2015757617 hasConceptScore W2015757617C2779609443 @default.
• W2015757617 hasConceptScore W2015757617C2780091579 @default.
• W2015757617 hasConceptScore W2015757617C2780306776 @default.
• W2015757617 hasConceptScore W2015757617C2909675724 @default.
• W2015757617 hasConceptScore W2015757617C2911091166 @default.
• W2015757617 hasConceptScore W2015757617C71924100 @default.
• W2015757617 hasConceptScore W2015757617C90924648 @default.
• W2015757617 hasIssue "1" @default.
• W2015757617 hasLocation W20157576171 @default.
• W2015757617 hasLocation W20157576172 @default.
• W2015757617 hasLocation W20157576173 @default.
• W2015757617 hasOpenAccess W2015757617 @default.
• W2015757617 hasPrimaryLocation W20157576171 @default.
• W2015757617 hasRelatedWork W150091706 @default.
• W2015757617 hasRelatedWork W1982197780 @default.
• W2015757617 hasRelatedWork W2027920270 @default.
• W2015757617 hasRelatedWork W2031796539 @default.
• W2015757617 hasRelatedWork W2063048952 @default.
• W2015757617 hasRelatedWork W2114862870 @default.
• W2015757617 hasRelatedWork W2136728678 @default.
• W2015757617 hasRelatedWork W2317216770 @default.
• W2015757617 hasRelatedWork W2905168405 @default.

• next