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- W2015760106 abstract "Generalized anxiety disorder (GAD) has undergone a series of revisions in its diagnostic criteria that has moved it, nosologically, away from its original affiliation with panic disorder (PD) and closer to major depressive disorder (MDD). This, together with its high comorbidity and putative shared genetic risk with MDD, has brought into question its place in future psychiatric nosology, prompting the planners of Diagnostic and Statistical Manual-V (DSM-V) and International Classification of Diseases-11 (ICD-11) to set up a workgroup tasked to better understand the relationship between GAD and MDD. This review attempts to summarize the extant data to compare GAD and MDD on a series of research validators to explore this relationship. Although insufficient data currently exist for GAD in several key validator classes, tentative conclusions can be drawn on the diagnostic status of GAD in relation to MDD. Although GAD possesses substantial overlap with MDD in the areas of genetics, childhood environment, demographics, and personality traits, this tends to hold true for other anxiety disorders (ADs) as well, with the strongest evidence for PD. Data from life events, personality disorders, biology, comorbidity, and pharmacology are mixed, showing some areas of similarity between GAD and MDD but some clear differences, again with a moderate degree of nonspecificity. Thus, although the bulk of evidence supports a close underlying relationship between them, the relatively nonspecific nature of these findings provides little more reason to question the nosologic validity of GAD in relation to MDD than that of some other anxiety disorders." @default.
- W2015760106 created "2016-06-24" @default.
- W2015760106 creator A5049231102 @default.
- W2015760106 date "2008-01-01" @default.
- W2015760106 modified "2023-10-18" @default.
- W2015760106 title "The nosologic relationship between generalized anxiety disorder and major depression" @default.
- W2015760106 cites W1487510422 @default.
- W2015760106 cites W1500442275 @default.
- W2015760106 cites W1597133836 @default.
- W2015760106 cites W1780570434 @default.
- W2015760106 cites W1936046240 @default.
- W2015760106 cites W1968143490 @default.
- W2015760106 cites W1968912840 @default.
- W2015760106 cites W1969219049 @default.
- W2015760106 cites W1969905759 @default.
- W2015760106 cites W1974119954 @default.
- W2015760106 cites W1975234279 @default.
- W2015760106 cites W1975429277 @default.
- W2015760106 cites W1975449695 @default.
- W2015760106 cites W1975582059 @default.
- W2015760106 cites W1976766779 @default.
- W2015760106 cites W1977130990 @default.
- W2015760106 cites W1980954965 @default.
- W2015760106 cites W1981166601 @default.
- W2015760106 cites W1981879624 @default.
- W2015760106 cites W1985966161 @default.
- W2015760106 cites W1986066265 @default.
- W2015760106 cites W1988021126 @default.
- W2015760106 cites W1989632226 @default.
- W2015760106 cites W1989756802 @default.
- W2015760106 cites W1990598466 @default.
- W2015760106 cites W1993652746 @default.
- W2015760106 cites W1996238645 @default.
- W2015760106 cites W1996770304 @default.
- W2015760106 cites W1997167800 @default.
- W2015760106 cites W2001670854 @default.
- W2015760106 cites W2003665168 @default.
- W2015760106 cites W2004884598 @default.
- W2015760106 cites W2005168332 @default.
- W2015760106 cites W2006466615 @default.
- W2015760106 cites W2008044753 @default.
- W2015760106 cites W2009575006 @default.
- W2015760106 cites W2014099171 @default.
- W2015760106 cites W2017163850 @default.
- W2015760106 cites W2017644223 @default.
- W2015760106 cites W2018195755 @default.
- W2015760106 cites W2018864947 @default.
- W2015760106 cites W2019180410 @default.
- W2015760106 cites W2020533083 @default.
- W2015760106 cites W2021606909 @default.
- W2015760106 cites W2023288605 @default.
- W2015760106 cites W2024136406 @default.
- W2015760106 cites W2026839049 @default.
- W2015760106 cites W2026904697 @default.
- W2015760106 cites W2027023991 @default.
- W2015760106 cites W2027512616 @default.
- W2015760106 cites W2028984168 @default.
- W2015760106 cites W2030745740 @default.
- W2015760106 cites W2036336555 @default.
- W2015760106 cites W2037612232 @default.
- W2015760106 cites W2037875799 @default.
- W2015760106 cites W2038671837 @default.
- W2015760106 cites W2040174390 @default.
- W2015760106 cites W2040975346 @default.
- W2015760106 cites W2042431879 @default.
- W2015760106 cites W2042561075 @default.
- W2015760106 cites W2044225822 @default.
- W2015760106 cites W2045566445 @default.
- W2015760106 cites W2045928247 @default.
- W2015760106 cites W2047605192 @default.
- W2015760106 cites W2048770447 @default.
- W2015760106 cites W2054154633 @default.
- W2015760106 cites W2057202132 @default.
- W2015760106 cites W2059403298 @default.
- W2015760106 cites W2059793861 @default.
- W2015760106 cites W2059943945 @default.
- W2015760106 cites W2061469083 @default.
- W2015760106 cites W2061620907 @default.
- W2015760106 cites W2063129418 @default.
- W2015760106 cites W2064542349 @default.
- W2015760106 cites W2065047452 @default.
- W2015760106 cites W2065319113 @default.
- W2015760106 cites W2067346060 @default.
- W2015760106 cites W2067908853 @default.
- W2015760106 cites W2070557630 @default.
- W2015760106 cites W2071872094 @default.
- W2015760106 cites W2073187326 @default.
- W2015760106 cites W2073969430 @default.
- W2015760106 cites W2077221760 @default.
- W2015760106 cites W2079210585 @default.
- W2015760106 cites W2079459508 @default.
- W2015760106 cites W2080113110 @default.
- W2015760106 cites W2086949224 @default.
- W2015760106 cites W2089523632 @default.
- W2015760106 cites W2091830114 @default.
- W2015760106 cites W2093594342 @default.
- W2015760106 cites W2097430457 @default.
- W2015760106 cites W2098906620 @default.