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- W2015762277 abstract "Abstract Virions of the Indiana serotype of vesicular stomatitis virus (VSV) grown in HKCC, BHK21-F, and MDBK cells have been found to differ considerably in their ability to agglutinate goose red blood cells and in their pH optimum for hemagglutination. Virions grown in HKCC cells had a specific hemagglutinating activity approximately 20 times greater than those grown in BHK21-F cells, and approximately 40 times greater than those grown in MDBK cells. The differences in activity and pH optima for hemagglutination were also found with the glycoprotein isolated from virions grown in the different cells. Carbohydrate analyses of the glycoproteins isolated from virions grown in the different cells revealed differences in carbohydrate composition. The observed differences in total carbohydrate and sialic acid content of the viral glycoproteins, and their correlation with differences in hemagglutinating activity provide additional evidence for a role of carbohydrate in virus-receptor interactions and suggest a chemical basis for the host-cell modification of the hemagglutinating activity of VSV." @default.
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- W2015762277 date "1978-01-01" @default.
- W2015762277 modified "2023-09-27" @default.
- W2015762277 title "Biological properties of the VSV glycoprotein II. Effects of the host cell and of the glycoprotein carbohydrate composition on hemagglutination" @default.
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- W2015762277 doi "https://doi.org/10.1016/0042-6822(78)90230-1" @default.
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