FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015762825> ?p ?o ?g. }

• W2015762825 endingPage "1915" @default.
• W2015762825 startingPage "1905" @default.
• W2015762825 abstract "Immunoglobulin metabolism has been studied in five patients with ataxia telangiectasia and in control subjects. Serum IgG levels were normal, increased, or decreased, reflecting normal, increased, or decreased synthetic rates, respectively. Serum IgM concentration was normal in three cases and slightly elevated in two cases. IgM turnover studies in the three cases with normal serum IgM levels showed normal IgM synthetic and catabolic rates. None of the five patients with ataxia telangiectasia had detectable serum IgA, and the maximum IgA synthetic rates possible for these patients were 0.3-10% of the normal mean synthetic rate (24 +/- 15 mg/kg per day) of 12 control individuals. Three of the patients had normal IgA fractional catabolic rates: 22% of the intravascular pool per day vs. 25 +/- 4% in controls. In two patients, fractional catabolic rates 4 and 20 times normal were found. In these cases, metabolic turnover, in vitro precipitation, radioimmunoelectrophoresis, and (or) the C'la fixation and transfer test provided evidence for the presence of a circulating antibody directed against IgA causing immune elimination of the molecule. These studies suggest that therapy with exogenous IgA may not be possible in some patients with ataxia telangiectasia or in other subjects with dysgammaglobulinemia." @default.
• W2015762825 created "2016-06-24" @default.
• W2015762825 creator A5035996420 @default.
• W2015762825 creator A5053370481 @default.
• W2015762825 creator A5078297998 @default.
• W2015762825 creator A5089402331 @default.
• W2015762825 creator A5089818751 @default.
• W2015762825 date "1968-08-01" @default.
• W2015762825 modified "2023-10-17" @default.
• W2015762825 title "Immunoglobulin metabolism in ataxia telangiectasia" @default.
• W2015762825 cites W1494751236 @default.
• W2015762825 cites W1502953431 @default.
• W2015762825 cites W1521884527 @default.
• W2015762825 cites W1550422636 @default.
• W2015762825 cites W1579364340 @default.
• W2015762825 cites W1673747382 @default.
• W2015762825 cites W1968137715 @default.
• W2015762825 cites W1987837841 @default.
• W2015762825 cites W1989743414 @default.
• W2015762825 cites W1991938977 @default.
• W2015762825 cites W1997170088 @default.
• W2015762825 cites W2030060086 @default.
• W2015762825 cites W2031518481 @default.
• W2015762825 cites W2049092390 @default.
• W2015762825 cites W2085649019 @default.
• W2015762825 cites W2114081495 @default.
• W2015762825 cites W2170435364 @default.
• W2015762825 cites W2411774299 @default.
• W2015762825 cites W2412751707 @default.
• W2015762825 cites W2414308677 @default.
• W2015762825 cites W2422031967 @default.
• W2015762825 cites W2443780297 @default.
• W2015762825 cites W2468921979 @default.
• W2015762825 cites W2470052815 @default.
• W2015762825 cites W2916161867 @default.
• W2015762825 cites W4300135757 @default.
• W2015762825 doi "https://doi.org/10.1172/jci105881" @default.
• W2015762825 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/297351" @default.
• W2015762825 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/4174353" @default.
• W2015762825 hasPublicationYear "1968" @default.
• W2015762825 type Work @default.
• W2015762825 sameAs 2015762825 @default.
• W2015762825 citedByCount "104" @default.
• W2015762825 countsByYear W20157628252012 @default.
• W2015762825 countsByYear W20157628252013 @default.
• W2015762825 countsByYear W20157628252015 @default.
• W2015762825 countsByYear W20157628252017 @default.
• W2015762825 countsByYear W20157628252019 @default.
• W2015762825 countsByYear W20157628252022 @default.
• W2015762825 crossrefType "journal-article" @default.
• W2015762825 hasAuthorship W2015762825A5035996420 @default.
• W2015762825 hasAuthorship W2015762825A5053370481 @default.
• W2015762825 hasAuthorship W2015762825A5078297998 @default.
• W2015762825 hasAuthorship W2015762825A5089402331 @default.
• W2015762825 hasAuthorship W2015762825A5089818751 @default.
• W2015762825 hasBestOaLocation W20157628251 @default.
• W2015762825 hasConcept C118552586 @default.
• W2015762825 hasConcept C126322002 @default.
• W2015762825 hasConcept C134018914 @default.
• W2015762825 hasConcept C143425029 @default.
• W2015762825 hasConcept C159654299 @default.
• W2015762825 hasConcept C185592680 @default.
• W2015762825 hasConcept C203014093 @default.
• W2015762825 hasConcept C2776553844 @default.
• W2015762825 hasConcept C2779486608 @default.
• W2015762825 hasConcept C2780898057 @default.
• W2015762825 hasConcept C2780906641 @default.
• W2015762825 hasConcept C552990157 @default.
• W2015762825 hasConcept C55493867 @default.
• W2015762825 hasConcept C62231903 @default.
• W2015762825 hasConcept C71924100 @default.
• W2015762825 hasConcept C8891405 @default.
• W2015762825 hasConcept C96942376 @default.
• W2015762825 hasConceptScore W2015762825C118552586 @default.
• W2015762825 hasConceptScore W2015762825C126322002 @default.
• W2015762825 hasConceptScore W2015762825C134018914 @default.
• W2015762825 hasConceptScore W2015762825C143425029 @default.
• W2015762825 hasConceptScore W2015762825C159654299 @default.
• W2015762825 hasConceptScore W2015762825C185592680 @default.
• W2015762825 hasConceptScore W2015762825C203014093 @default.
• W2015762825 hasConceptScore W2015762825C2776553844 @default.
• W2015762825 hasConceptScore W2015762825C2779486608 @default.
• W2015762825 hasConceptScore W2015762825C2780898057 @default.
• W2015762825 hasConceptScore W2015762825C2780906641 @default.
• W2015762825 hasConceptScore W2015762825C552990157 @default.
• W2015762825 hasConceptScore W2015762825C55493867 @default.
• W2015762825 hasConceptScore W2015762825C62231903 @default.
• W2015762825 hasConceptScore W2015762825C71924100 @default.
• W2015762825 hasConceptScore W2015762825C8891405 @default.
• W2015762825 hasConceptScore W2015762825C96942376 @default.
• W2015762825 hasIssue "8" @default.
• W2015762825 hasLocation W20157628251 @default.
• W2015762825 hasLocation W20157628252 @default.
• W2015762825 hasLocation W20157628253 @default.
• W2015762825 hasLocation W20157628254 @default.
• W2015762825 hasOpenAccess W2015762825 @default.
• W2015762825 hasPrimaryLocation W20157628251 @default.
• W2015762825 hasRelatedWork W1624768411 @default.

• next