Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015776364> ?p ?o ?g. }
- W2015776364 endingPage "102" @default.
- W2015776364 startingPage "93" @default.
- W2015776364 abstract "Although fractalkine is one of chemokines involved in mediation of neuronal/microglial interaction, it is not known whether fractalkine/CX3CR1-mediated pathogenesis occurs in the rat brain following epileptogenic insults. In order to elucidate the roles of the fractalkine/CX3CR1 system in microglial activation and neurodegeneration induced by status epilepticus (SE), we investigated changes in fractalkine/CX3CR1 system within the rat hippocampus following SE. In non-SE induced animals, fractalkine and CX3CR1 immunoreactivity was detected in neurons and microglia, respectively. Following SE, fractalkine immunoreactivity was transiently increased in neurons and astrocytes. CX3CR1 immunoreactivity was also transiently detected in neurons (particularly in CA1 pyramidal cells). Intracerebroventricular infusions of recombinant rat fractalkine aggravated SE-induced neuronal damage, while fractalkine IgG or CX3CR1 IgG infusion alleviated it, compared to saline-infused animals. These findings suggest that fractalkine/CX3CR1 system may play an important role in SE-induced neuronal damages via neuron-microglial interactions." @default.
- W2015776364 created "2016-06-24" @default.
- W2015776364 creator A5008839438 @default.
- W2015776364 creator A5014032667 @default.
- W2015776364 creator A5024130459 @default.
- W2015776364 creator A5032066510 @default.
- W2015776364 creator A5034434745 @default.
- W2015776364 creator A5043236626 @default.
- W2015776364 creator A5074393627 @default.
- W2015776364 creator A5075211999 @default.
- W2015776364 date "2011-05-01" @default.
- W2015776364 modified "2023-10-17" @default.
- W2015776364 title "The roles of fractalkine/CX3CR1 system in neuronal death following pilocarpine-induced status epilepticus" @default.
- W2015776364 cites W1588041244 @default.
- W2015776364 cites W1600863966 @default.
- W2015776364 cites W1666500994 @default.
- W2015776364 cites W1906305879 @default.
- W2015776364 cites W1973251099 @default.
- W2015776364 cites W1973792237 @default.
- W2015776364 cites W1974437785 @default.
- W2015776364 cites W1983609063 @default.
- W2015776364 cites W1989400013 @default.
- W2015776364 cites W1997577480 @default.
- W2015776364 cites W1999406702 @default.
- W2015776364 cites W2003907850 @default.
- W2015776364 cites W2007287932 @default.
- W2015776364 cites W2014495235 @default.
- W2015776364 cites W2022850181 @default.
- W2015776364 cites W2031937367 @default.
- W2015776364 cites W2032618901 @default.
- W2015776364 cites W2033242795 @default.
- W2015776364 cites W2042452988 @default.
- W2015776364 cites W2042762178 @default.
- W2015776364 cites W2052193782 @default.
- W2015776364 cites W2056741090 @default.
- W2015776364 cites W2063620427 @default.
- W2015776364 cites W2069328624 @default.
- W2015776364 cites W2071832924 @default.
- W2015776364 cites W2079841860 @default.
- W2015776364 cites W2083187514 @default.
- W2015776364 cites W2088542086 @default.
- W2015776364 cites W2091028315 @default.
- W2015776364 cites W2092317826 @default.
- W2015776364 cites W2096330567 @default.
- W2015776364 cites W2096738792 @default.
- W2015776364 cites W2100625035 @default.
- W2015776364 cites W2103946141 @default.
- W2015776364 cites W2113107925 @default.
- W2015776364 cites W2113125119 @default.
- W2015776364 cites W2122311980 @default.
- W2015776364 cites W2132852509 @default.
- W2015776364 cites W2144414931 @default.
- W2015776364 cites W2148780480 @default.
- W2015776364 cites W2149352351 @default.
- W2015776364 cites W2163487275 @default.
- W2015776364 cites W4210981518 @default.
- W2015776364 cites W4233844040 @default.
- W2015776364 cites W4238201436 @default.
- W2015776364 cites W4376522459 @default.
- W2015776364 doi "https://doi.org/10.1016/j.jneuroim.2011.03.005" @default.
- W2015776364 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21481949" @default.
- W2015776364 hasPublicationYear "2011" @default.
- W2015776364 type Work @default.
- W2015776364 sameAs 2015776364 @default.
- W2015776364 citedByCount "38" @default.
- W2015776364 countsByYear W20157763642012 @default.
- W2015776364 countsByYear W20157763642013 @default.
- W2015776364 countsByYear W20157763642014 @default.
- W2015776364 countsByYear W20157763642015 @default.
- W2015776364 countsByYear W20157763642016 @default.
- W2015776364 countsByYear W20157763642017 @default.
- W2015776364 countsByYear W20157763642018 @default.
- W2015776364 countsByYear W20157763642019 @default.
- W2015776364 countsByYear W20157763642020 @default.
- W2015776364 countsByYear W20157763642021 @default.
- W2015776364 countsByYear W20157763642022 @default.
- W2015776364 countsByYear W20157763642023 @default.
- W2015776364 crossrefType "journal-article" @default.
- W2015776364 hasAuthorship W2015776364A5008839438 @default.
- W2015776364 hasAuthorship W2015776364A5014032667 @default.
- W2015776364 hasAuthorship W2015776364A5024130459 @default.
- W2015776364 hasAuthorship W2015776364A5032066510 @default.
- W2015776364 hasAuthorship W2015776364A5034434745 @default.
- W2015776364 hasAuthorship W2015776364A5043236626 @default.
- W2015776364 hasAuthorship W2015776364A5074393627 @default.
- W2015776364 hasAuthorship W2015776364A5075211999 @default.
- W2015776364 hasConcept C12823836 @default.
- W2015776364 hasConcept C13373296 @default.
- W2015776364 hasConcept C169760540 @default.
- W2015776364 hasConcept C203014093 @default.
- W2015776364 hasConcept C2776914184 @default.
- W2015776364 hasConcept C2777341932 @default.
- W2015776364 hasConcept C2778186239 @default.
- W2015776364 hasConcept C2778794669 @default.
- W2015776364 hasConcept C2779830541 @default.
- W2015776364 hasConcept C2781161787 @default.
- W2015776364 hasConcept C31179232 @default.
- W2015776364 hasConcept C529278444 @default.