FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015776844> ?p ?o ?g. }

• W2015776844 endingPage "971" @default.
• W2015776844 startingPage "967" @default.
• W2015776844 abstract "Most evidence indicates that nitric oxide plays a role in normal wound repair; however, involvement of inducible nitric oxide synthase (iNOS) has not been established. Experiments were carried out to determine the requirement for iNOS in closing excisional wounds. Wound closure was delayed by 31% in iNOS knockout mice compared with wild-type animals. An identical delay in wound closure was observed in wild-type mice given a continuous infusion of the partially selective iNOS inhibitor N6-(iminoethyl)-L-lysine. Delayed wound healing in iNOS-deficient mice was completely reversed by a single application of an adenoviral vector containing human iNOS cDNA (AdiNOS) at the time of wounding. Reverse transcription PCR identified iNOS mRNA expression in wild-type mice peaking 4-6 d after wounding, and confirmed expression of human iNOS in the adenoviral vector containing human iNOS cDNA-treated animals. These results establish the key role of iNOS in wound closure, and suggest a gene therapy strategy to improve wound healing in iNOS-deficient states such as diabetes, and during steroid treatment." @default.
• W2015776844 created "2016-06-24" @default.
• W2015776844 creator A5014661028 @default.
• W2015776844 creator A5044094233 @default.
• W2015776844 creator A5045929439 @default.
• W2015776844 creator A5047383033 @default.
• W2015776844 creator A5061598858 @default.
• W2015776844 creator A5062076820 @default.
• W2015776844 creator A5086424576 @default.
• W2015776844 creator A5033910876 @default.
• W2015776844 date "1998-03-01" @default.
• W2015776844 modified "2023-10-09" @default.
• W2015776844 title "Reversal of impaired wound repair in iNOS-deficient mice by topical adenoviral-mediated iNOS gene transfer." @default.
• W2015776844 cites W1004999796 @default.
• W2015776844 cites W1527590544 @default.
• W2015776844 cites W1573977017 @default.
• W2015776844 cites W1591059007 @default.
• W2015776844 cites W1653031648 @default.
• W2015776844 cites W1791996532 @default.
• W2015776844 cites W1980469816 @default.
• W2015776844 cites W2004343006 @default.
• W2015776844 cites W201336786 @default.
• W2015776844 cites W2016687652 @default.
• W2015776844 cites W2016734498 @default.
• W2015776844 cites W2022322596 @default.
• W2015776844 cites W2024191096 @default.
• W2015776844 cites W2044296969 @default.
• W2015776844 cites W2050888716 @default.
• W2015776844 cites W2073973931 @default.
• W2015776844 cites W2077170654 @default.
• W2015776844 cites W2122515902 @default.
• W2015776844 cites W2143260418 @default.
• W2015776844 cites W2160997491 @default.
• W2015776844 cites W2236768440 @default.
• W2015776844 cites W2337306684 @default.
• W2015776844 cites W237380194 @default.
• W2015776844 cites W2397589134 @default.
• W2015776844 doi "https://doi.org/10.1172/jci2067" @default.
• W2015776844 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/508647" @default.
• W2015776844 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/9486966" @default.
• W2015776844 hasPublicationYear "1998" @default.
• W2015776844 type Work @default.
• W2015776844 sameAs 2015776844 @default.
• W2015776844 citedByCount "407" @default.
• W2015776844 countsByYear W20157768442012 @default.
• W2015776844 countsByYear W20157768442013 @default.
• W2015776844 countsByYear W20157768442014 @default.
• W2015776844 countsByYear W20157768442015 @default.
• W2015776844 countsByYear W20157768442016 @default.
• W2015776844 countsByYear W20157768442017 @default.
• W2015776844 countsByYear W20157768442018 @default.
• W2015776844 countsByYear W20157768442019 @default.
• W2015776844 countsByYear W20157768442020 @default.
• W2015776844 countsByYear W20157768442021 @default.
• W2015776844 countsByYear W20157768442022 @default.
• W2015776844 countsByYear W20157768442023 @default.
• W2015776844 crossrefType "journal-article" @default.
• W2015776844 hasAuthorship W2015776844A5014661028 @default.
• W2015776844 hasAuthorship W2015776844A5033910876 @default.
• W2015776844 hasAuthorship W2015776844A5044094233 @default.
• W2015776844 hasAuthorship W2015776844A5045929439 @default.
• W2015776844 hasAuthorship W2015776844A5047383033 @default.
• W2015776844 hasAuthorship W2015776844A5061598858 @default.
• W2015776844 hasAuthorship W2015776844A5062076820 @default.
• W2015776844 hasAuthorship W2015776844A5086424576 @default.
• W2015776844 hasBestOaLocation W20157768441 @default.
• W2015776844 hasConcept C104317684 @default.
• W2015776844 hasConcept C111599444 @default.
• W2015776844 hasConcept C134018914 @default.
• W2015776844 hasConcept C153911025 @default.
• W2015776844 hasConcept C182704531 @default.
• W2015776844 hasConcept C203014093 @default.
• W2015776844 hasConcept C2777622882 @default.
• W2015776844 hasConcept C2780269544 @default.
• W2015776844 hasConcept C32470452 @default.
• W2015776844 hasConcept C40767141 @default.
• W2015776844 hasConcept C519581460 @default.
• W2015776844 hasConcept C55493867 @default.
• W2015776844 hasConcept C86803240 @default.
• W2015776844 hasConcept C98274493 @default.
• W2015776844 hasConceptScore W2015776844C104317684 @default.
• W2015776844 hasConceptScore W2015776844C111599444 @default.
• W2015776844 hasConceptScore W2015776844C134018914 @default.
• W2015776844 hasConceptScore W2015776844C153911025 @default.
• W2015776844 hasConceptScore W2015776844C182704531 @default.
• W2015776844 hasConceptScore W2015776844C203014093 @default.
• W2015776844 hasConceptScore W2015776844C2777622882 @default.
• W2015776844 hasConceptScore W2015776844C2780269544 @default.
• W2015776844 hasConceptScore W2015776844C32470452 @default.
• W2015776844 hasConceptScore W2015776844C40767141 @default.
• W2015776844 hasConceptScore W2015776844C519581460 @default.
• W2015776844 hasConceptScore W2015776844C55493867 @default.
• W2015776844 hasConceptScore W2015776844C86803240 @default.
• W2015776844 hasConceptScore W2015776844C98274493 @default.
• W2015776844 hasIssue "5" @default.
• W2015776844 hasLocation W20157768441 @default.
• W2015776844 hasLocation W20157768442 @default.
• W2015776844 hasLocation W20157768443 @default.

• next