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- W2015784103 abstract "Rats exhibiting steady self-stimulation behavior were allowed to regulate the duration of hypothalamic stimulation during concomitant painful footshock. Results show that the mean duration of bar pressing increases with the incrementation of the footshock voltage. Furthermore, the incrementation of the brain stimulation depends on the rewarding value elicited by the hypothalamic stimulation. The less the intracranial stimulation is rewarding, the more the animal increases brain stimulation, and vice versa . Several hypotheses are presented to explain the mechanism underlying the compensation behavior by increasing the consummation of rewarding electrical stimuli during concomitant footshock. Finally, the verification of three conditions supports the hypothesis of an attenuation of nociceptive effects by the stimulation of rewarding brain area. These conditions are the following: (1) the rewarding brain region and the region responsible for pain-suppression, when excited, had to be separated; (2) the painful stimulation must stay aversive despite the rewarding brain stimulation; (3) a close relationship between the rewarding intensity elicited and the intensity of the nociceptive stimulation." @default.
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- W2015784103 title "Compensatory effects of hypothalamic rewarding stimulation during concomitant painful footshock" @default.
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- W2015784103 doi "https://doi.org/10.1016/0031-9384(79)90004-0" @default.
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