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- W2015807897 abstract "A sensitive LC-MS-MS method capable of quantifying terfenadine at levels down to 100 pg ml−1 in human plasma is reported. The method was validated over a linear range from 0.1 to 5.0 ng ml−1 using a liquid-liquid extraction with a deuterium-labelled internal standard. The between-run precision and accuracy of the calibration standards were 2.6–6.0% RSD and −2.0 to +2.2% relative error (RE). The between-run and within-run precision and accuracy of quality control samples (0.3, 1.5 and 3.5 ng ml−1) were 1.0–5.9% RSD and +1.7 to +6.3% RE. This method was applied to the analysis of human plasma samples." @default.
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- W2015807897 date "1996-09-01" @default.
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- W2015807897 title "Development and validation of an LC-MS-MS method for the determination of terfenadine in human plasma" @default.
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- W2015807897 doi "https://doi.org/10.1016/0731-7085(96)01804-3" @default.
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