Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015833166> ?p ?o ?g. }
- W2015833166 abstract "A growing body of research suggests that curcumin, the major active constituent of the dietary spice turmeric, has potential for the prevention and therapy of cancer. Preclinical data have shown that curcumin can both inhibit the formation of tumors in animal models of carcinogenesis and act on a variety of molecular targets involved in cancer development. In vitro studies have demonstrated that curcumin is an efficient inducer of apoptosis and some degree of selectivity for cancer cells has been observed. Clinical trials have revealed that curcumin is well tolerated and may produce antitumor effects in people with precancerous lesions or who are at a high risk for developing cancer. This seems to indicate that curcumin is a pharmacologically safe agent that may be used in cancer chemoprevention and therapy. Both in vitro and in vivo studies have shown, however, that curcumin may produce toxic and carcinogenic effects under specific conditions. Curcumin may also alter the effectiveness of radiotherapy and chemotherapy. This review article analyzes the in vitro and in vivo cancer-related activities of curcumin and discusses that they are linked to its known antioxidant and pro-oxidant properties. Several considerations that may help develop curcumin as an anticancer agent are also discussed." @default.
- W2015833166 created "2016-06-24" @default.
- W2015833166 creator A5051071578 @default.
- W2015833166 date "2008-05-21" @default.
- W2015833166 modified "2023-09-30" @default.
- W2015833166 title "Anticancer and carcinogenic properties of curcumin: Considerations for its clinical development as a cancer chemopreventive and chemotherapeutic agent" @default.
- W2015833166 cites W106969692 @default.
- W2015833166 cites W110788161 @default.
- W2015833166 cites W1482076735 @default.
- W2015833166 cites W1506756493 @default.
- W2015833166 cites W15353513 @default.
- W2015833166 cites W1540863311 @default.
- W2015833166 cites W1547863599 @default.
- W2015833166 cites W1553705768 @default.
- W2015833166 cites W1559110433 @default.
- W2015833166 cites W1664719478 @default.
- W2015833166 cites W175416543 @default.
- W2015833166 cites W1789143826 @default.
- W2015833166 cites W1827885532 @default.
- W2015833166 cites W1850020125 @default.
- W2015833166 cites W1878987344 @default.
- W2015833166 cites W1925429192 @default.
- W2015833166 cites W1935939906 @default.
- W2015833166 cites W1964072158 @default.
- W2015833166 cites W1964232812 @default.
- W2015833166 cites W1964949922 @default.
- W2015833166 cites W1965402438 @default.
- W2015833166 cites W1965734230 @default.
- W2015833166 cites W1965989247 @default.
- W2015833166 cites W1967285600 @default.
- W2015833166 cites W1967291007 @default.
- W2015833166 cites W1967685864 @default.
- W2015833166 cites W1967897952 @default.
- W2015833166 cites W1969608503 @default.
- W2015833166 cites W1969815998 @default.
- W2015833166 cites W1970546156 @default.
- W2015833166 cites W1970564305 @default.
- W2015833166 cites W1970853130 @default.
- W2015833166 cites W1970929283 @default.
- W2015833166 cites W1971781743 @default.
- W2015833166 cites W1971998915 @default.
- W2015833166 cites W1972519024 @default.
- W2015833166 cites W1972685575 @default.
- W2015833166 cites W1972733003 @default.
- W2015833166 cites W1975411070 @default.
- W2015833166 cites W1975737582 @default.
- W2015833166 cites W1976235867 @default.
- W2015833166 cites W1976604861 @default.
- W2015833166 cites W1977332969 @default.
- W2015833166 cites W1980008351 @default.
- W2015833166 cites W1980957444 @default.
- W2015833166 cites W1981657616 @default.
- W2015833166 cites W1982995596 @default.
- W2015833166 cites W1984474728 @default.
- W2015833166 cites W1985049657 @default.
- W2015833166 cites W1985864418 @default.
- W2015833166 cites W1985945529 @default.
- W2015833166 cites W1986499908 @default.
- W2015833166 cites W1987767943 @default.
- W2015833166 cites W1988369476 @default.
- W2015833166 cites W1989646379 @default.
- W2015833166 cites W1990991016 @default.
- W2015833166 cites W1991327193 @default.
- W2015833166 cites W1992652784 @default.
- W2015833166 cites W1993701704 @default.
- W2015833166 cites W1995804072 @default.
- W2015833166 cites W1995934014 @default.
- W2015833166 cites W1995997034 @default.
- W2015833166 cites W1997446186 @default.
- W2015833166 cites W1997614694 @default.
- W2015833166 cites W1997769427 @default.
- W2015833166 cites W1998742968 @default.
- W2015833166 cites W2001337676 @default.
- W2015833166 cites W2001356850 @default.
- W2015833166 cites W2001723288 @default.
- W2015833166 cites W2001964336 @default.
- W2015833166 cites W2002135269 @default.
- W2015833166 cites W2002801265 @default.
- W2015833166 cites W2002831133 @default.
- W2015833166 cites W2003195335 @default.
- W2015833166 cites W2005020033 @default.
- W2015833166 cites W2007108460 @default.
- W2015833166 cites W2007255257 @default.
- W2015833166 cites W2007299371 @default.
- W2015833166 cites W2008061478 @default.
- W2015833166 cites W2008677094 @default.
- W2015833166 cites W2008783997 @default.
- W2015833166 cites W2009039680 @default.
- W2015833166 cites W2009139905 @default.
- W2015833166 cites W2010073511 @default.
- W2015833166 cites W2010839968 @default.
- W2015833166 cites W2011006722 @default.
- W2015833166 cites W2011085845 @default.
- W2015833166 cites W2011631594 @default.
- W2015833166 cites W2011810742 @default.
- W2015833166 cites W2011912935 @default.
- W2015833166 cites W2011993914 @default.
- W2015833166 cites W2012067240 @default.
- W2015833166 cites W2012367306 @default.
- W2015833166 cites W2012726347 @default.