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- W2015835353 abstract "Plaque rupture is the main cause of myocardial infarctions and strokes. Ruptured plaques have thin, highly inflamed, and collagen-poor fibrous caps that contain elevated levels of proteases, including metalloproteinases (MMPs), which might weaken plaque caps and promote rupture. On the other hand, MMPs facilitate migration and proliferation vascular smooth muscle cells, which should promote fibrous cap stability. Given the dual effects of MMPs, therapies should selectively target harmful MMPs or the processes that cause MMP activity to rise to destructive levels." @default.
- W2015835353 created "2016-06-24" @default.
- W2015835353 creator A5069151365 @default.
- W2015835353 date "2007-11-01" @default.
- W2015835353 modified "2023-09-27" @default.
- W2015835353 title "Metalloproteinases and Vulnerable Atherosclerotic Plaques" @default.
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- W2015835353 doi "https://doi.org/10.1016/j.tcm.2007.09.001" @default.
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