Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015842257> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2015842257 endingPage "40" @default.
- W2015842257 startingPage "27" @default.
- W2015842257 abstract "The Drosophila mutation, quartet, affects development at points in the life cycle that require intense mitotic activity. Examination of embryos affected by the maternal effect of quartet has revealed defects that can be attributed to incomplete chromosome separation at mitosis. These defects include uneven spacing of nuclei, strands of DNA creating bridges between nuclei, and abnormal amounts of DNA per nucleus. Nuclei in quartet-affected embryos also have a greater-than-normal number of centrosomes. Immunofluorescent examination of the spindles in quartet-affected embryos has revealed tripolar spindles and adjacent spindles that share a common spindle pole. Finally, chromosome separation distance was measured in anaphase and telophase spindles in quartet-affected embryos and found to be blocked in anaphase. Examination of mitotic figures in quartet larvae revealed a reduced mitotic index and an elevated frequency of abnormal mitotic figures. quartet could encode a function necessary for the disengagement of chromosomes in mitosis, for kinetochore function or for function of a spindle motor. Mutations in quartet prevent the post-translational modification of three abundant proteins. These proteins may be involved in chromosome separation in mitosis." @default.
- W2015842257 created "2016-06-24" @default.
- W2015842257 creator A5046684535 @default.
- W2015842257 creator A5058636832 @default.
- W2015842257 date "1990-01-01" @default.
- W2015842257 modified "2023-10-14" @default.
- W2015842257 title "Quartet: ADrosophila developmental mutation affecting chromosome separation in mitosis" @default.
- W2015842257 cites W1781095925 @default.
- W2015842257 cites W1924895133 @default.
- W2015842257 cites W1972649837 @default.
- W2015842257 cites W1975680335 @default.
- W2015842257 cites W1991689596 @default.
- W2015842257 cites W2009261150 @default.
- W2015842257 cites W2014753175 @default.
- W2015842257 cites W2024571097 @default.
- W2015842257 cites W2042882869 @default.
- W2015842257 cites W2066095990 @default.
- W2015842257 cites W2077918922 @default.
- W2015842257 cites W2085609768 @default.
- W2015842257 cites W2096894672 @default.
- W2015842257 cites W2107995356 @default.
- W2015842257 cites W2150354298 @default.
- W2015842257 cites W2321998264 @default.
- W2015842257 cites W2416298690 @default.
- W2015842257 doi "https://doi.org/10.1002/dvg.1020110105" @default.
- W2015842257 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2193767" @default.
- W2015842257 hasPublicationYear "1990" @default.
- W2015842257 type Work @default.
- W2015842257 sameAs 2015842257 @default.
- W2015842257 citedByCount "8" @default.
- W2015842257 crossrefType "journal-article" @default.
- W2015842257 hasAuthorship W2015842257A5046684535 @default.
- W2015842257 hasAuthorship W2015842257A5058636832 @default.
- W2015842257 hasConcept C104317684 @default.
- W2015842257 hasConcept C10447061 @default.
- W2015842257 hasConcept C141561535 @default.
- W2015842257 hasConcept C1491633281 @default.
- W2015842257 hasConcept C29537977 @default.
- W2015842257 hasConcept C30481170 @default.
- W2015842257 hasConcept C53420372 @default.
- W2015842257 hasConcept C54355233 @default.
- W2015842257 hasConcept C86803240 @default.
- W2015842257 hasConcept C93304396 @default.
- W2015842257 hasConcept C95444343 @default.
- W2015842257 hasConceptScore W2015842257C104317684 @default.
- W2015842257 hasConceptScore W2015842257C10447061 @default.
- W2015842257 hasConceptScore W2015842257C141561535 @default.
- W2015842257 hasConceptScore W2015842257C1491633281 @default.
- W2015842257 hasConceptScore W2015842257C29537977 @default.
- W2015842257 hasConceptScore W2015842257C30481170 @default.
- W2015842257 hasConceptScore W2015842257C53420372 @default.
- W2015842257 hasConceptScore W2015842257C54355233 @default.
- W2015842257 hasConceptScore W2015842257C86803240 @default.
- W2015842257 hasConceptScore W2015842257C93304396 @default.
- W2015842257 hasConceptScore W2015842257C95444343 @default.
- W2015842257 hasIssue "1" @default.
- W2015842257 hasLocation W20158422571 @default.
- W2015842257 hasLocation W20158422572 @default.
- W2015842257 hasOpenAccess W2015842257 @default.
- W2015842257 hasPrimaryLocation W20158422571 @default.
- W2015842257 hasRelatedWork W2005892444 @default.
- W2015842257 hasRelatedWork W2028847444 @default.
- W2015842257 hasRelatedWork W2060384429 @default.
- W2015842257 hasRelatedWork W2066309710 @default.
- W2015842257 hasRelatedWork W2091909051 @default.
- W2015842257 hasRelatedWork W2096480940 @default.
- W2015842257 hasRelatedWork W2162705610 @default.
- W2015842257 hasRelatedWork W2275386138 @default.
- W2015842257 hasRelatedWork W2409106442 @default.
- W2015842257 hasRelatedWork W3026187102 @default.
- W2015842257 hasVolume "11" @default.
- W2015842257 isParatext "false" @default.
- W2015842257 isRetracted "false" @default.
- W2015842257 magId "2015842257" @default.
- W2015842257 workType "article" @default.