Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015854906> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W2015854906 endingPage "870" @default.
- W2015854906 startingPage "863" @default.
- W2015854906 abstract "Though hydrogen peroxide (<TEX>$H_2O_2$</TEX>) causes a deleterious effect to cells with its reactive oxygen species resulting in cell death, S-allyl cysteine (SAC, a bioactive organosulfur compound of aged garlic extract) has been known to have a cytoprotective effect. Few reported profiles of gene expression of <TEX>$H_2O_2$</TEX> and SAC treated human cord blood derived mesenchymal stem cells (MSC). This study revealed changes in the profile of twenty-one genes grouped by oxidative stress, antioxidant, cell death, anti-apoptosis and anti-aging by quantitative real time PCR. A concentration of <TEX>$100{mu}M$</TEX> of SAC or <TEX>$50{mu}M$</TEX> of <TEX>$H_2O_2$</TEX> was applied to MSC which show moderate growth and apoptosis pattern. <TEX>$H_2O_2$</TEX> treatment enhanced expression of eleven genes out of twenty-one genes compared with that of control group, on the contrary SAC suppressed expression of eighteen genes out of twenty-one genes except C ros oncogene. SAC decreased expression of oxidative stress genes such as SOD1, CAT and GPX. These results seemed consistent with reports which elucidated over-expression of NF-<TEX>${kappa}$</TEX>B by <TEX>$H_2O_2$</TEX>, and suppression of it by SAC. This study will confer basic information for further experiments regarding the effects of SAC on gene levels." @default.
- W2015854906 created "2016-06-24" @default.
- W2015854906 creator A5046863127 @default.
- W2015854906 date "2012-12-31" @default.
- W2015854906 modified "2023-09-25" @default.
- W2015854906 title "Gene Profile of Mesenchymal Stem Cell Induced by SAC or Hydrogen Peroxide (H2O2)" @default.
- W2015854906 cites W1581260482 @default.
- W2015854906 cites W1933364203 @default.
- W2015854906 cites W1943303117 @default.
- W2015854906 cites W1967178128 @default.
- W2015854906 cites W1979449739 @default.
- W2015854906 cites W1997204785 @default.
- W2015854906 cites W2001514098 @default.
- W2015854906 cites W2013336783 @default.
- W2015854906 cites W2020535315 @default.
- W2015854906 cites W2026433593 @default.
- W2015854906 cites W2026558983 @default.
- W2015854906 cites W2027785748 @default.
- W2015854906 cites W2027925291 @default.
- W2015854906 cites W2041897873 @default.
- W2015854906 cites W2058639324 @default.
- W2015854906 cites W2079838652 @default.
- W2015854906 cites W2091526175 @default.
- W2015854906 cites W2103977809 @default.
- W2015854906 cites W2111590623 @default.
- W2015854906 cites W2112862143 @default.
- W2015854906 cites W2114388285 @default.
- W2015854906 cites W2154441223 @default.
- W2015854906 cites W2159999899 @default.
- W2015854906 cites W2160823360 @default.
- W2015854906 doi "https://doi.org/10.9799/ksfan.2012.25.4.863" @default.
- W2015854906 hasPublicationYear "2012" @default.
- W2015854906 type Work @default.
- W2015854906 sameAs 2015854906 @default.
- W2015854906 citedByCount "1" @default.
- W2015854906 countsByYear W20158549062014 @default.
- W2015854906 crossrefType "journal-article" @default.
- W2015854906 hasAuthorship W2015854906A5046863127 @default.
- W2015854906 hasConcept C104317684 @default.
- W2015854906 hasConcept C150194340 @default.
- W2015854906 hasConcept C153911025 @default.
- W2015854906 hasConcept C185592680 @default.
- W2015854906 hasConcept C190283241 @default.
- W2015854906 hasConcept C198826908 @default.
- W2015854906 hasConcept C2776151105 @default.
- W2015854906 hasConcept C31573885 @default.
- W2015854906 hasConcept C48349386 @default.
- W2015854906 hasConcept C533411734 @default.
- W2015854906 hasConcept C55493867 @default.
- W2015854906 hasConcept C86803240 @default.
- W2015854906 hasConcept C95444343 @default.
- W2015854906 hasConceptScore W2015854906C104317684 @default.
- W2015854906 hasConceptScore W2015854906C150194340 @default.
- W2015854906 hasConceptScore W2015854906C153911025 @default.
- W2015854906 hasConceptScore W2015854906C185592680 @default.
- W2015854906 hasConceptScore W2015854906C190283241 @default.
- W2015854906 hasConceptScore W2015854906C198826908 @default.
- W2015854906 hasConceptScore W2015854906C2776151105 @default.
- W2015854906 hasConceptScore W2015854906C31573885 @default.
- W2015854906 hasConceptScore W2015854906C48349386 @default.
- W2015854906 hasConceptScore W2015854906C533411734 @default.
- W2015854906 hasConceptScore W2015854906C55493867 @default.
- W2015854906 hasConceptScore W2015854906C86803240 @default.
- W2015854906 hasConceptScore W2015854906C95444343 @default.
- W2015854906 hasIssue "4" @default.
- W2015854906 hasLocation W20158549061 @default.
- W2015854906 hasOpenAccess W2015854906 @default.
- W2015854906 hasPrimaryLocation W20158549061 @default.
- W2015854906 hasRelatedWork W1982440565 @default.
- W2015854906 hasRelatedWork W2010506957 @default.
- W2015854906 hasRelatedWork W2023797581 @default.
- W2015854906 hasRelatedWork W2061260890 @default.
- W2015854906 hasRelatedWork W2077568460 @default.
- W2015854906 hasRelatedWork W2190837461 @default.
- W2015854906 hasRelatedWork W2347577273 @default.
- W2015854906 hasRelatedWork W2381884082 @default.
- W2015854906 hasRelatedWork W2621169341 @default.
- W2015854906 hasRelatedWork W3217798852 @default.
- W2015854906 hasVolume "25" @default.
- W2015854906 isParatext "false" @default.
- W2015854906 isRetracted "false" @default.
- W2015854906 magId "2015854906" @default.
- W2015854906 workType "article" @default.