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• W2015865718 abstract "Significance Peptides and their specific receptors form molecular peptidergic systems (PSs) that are essential components of neuronal communication in the animal brain. Many PSs have been characterized in insects and mammals but their precise evolutionary relationship is not fully understood. We interrogated genomic sequence databases and used phylogenetic reconstruction tools to show that a large fraction of human PSs were already present in the last common ancestor of flies, mollusks, urchins, and mammals. Our analysis provides a comprehensive view of animal PSs that will pave the way for comparative studies leading to a better understanding of animal physiology and behavior." @default.
• W2015865718 created "2016-06-24" @default.
• W2015865718 creator A5029137625 @default.
• W2015865718 creator A5061242249 @default.
• W2015865718 date "2013-05-13" @default.
• W2015865718 modified "2023-10-13" @default.
• W2015865718 title "Molecular evolution of peptidergic signaling systems in bilaterians" @default.
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• W2015865718 doi "https://doi.org/10.1073/pnas.1219956110" @default.
• W2015865718 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3670399" @default.
• W2015865718 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23671109" @default.
• W2015865718 hasPublicationYear "2013" @default.
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