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- W2015879192 abstract "This review summarises current knowledge of polyamine-containing spider toxins and their interactions with ionotropic receptors of invertebrate and vertebrate excitable cells. Their diverse actions on ionotropic glutamate and acetylcholine receptors, which include potentiation, closed channel block and open channel block, are discussed in the context of toxin and target structures. Factors that complicate attempts to identify and pharmacologically characterise the binding sites for these toxins include their ability to permeate channels of some ionotropic receptors and their apparent accumulation in a cellular compartment, possibly the membrane bilayer." @default.
- W2015879192 created "2016-06-24" @default.
- W2015879192 creator A5054900682 @default.
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- W2015879192 date "2004-04-01" @default.
- W2015879192 modified "2023-09-28" @default.
- W2015879192 title "Targeting ionotropic receptors with polyamine-containing toxins☆" @default.
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- W2015879192 doi "https://doi.org/10.1016/j.toxicon.2004.02.003" @default.
- W2015879192 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/15066409" @default.
- W2015879192 hasPublicationYear "2004" @default.
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