FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015881576> ?p ?o ?g. }

• W2015881576 endingPage "4611" @default.
• W2015881576 startingPage "4603" @default.
• W2015881576 abstract "Dental composite materials contain polymers of methacrylates, which, due to mechanical abrasion and enzymatic action of saliva, may release their monomers into oral cavity and the pulp. Moreover, polymerization is always incomplete and leaves usually considerable fraction of free monomers. Mechanisms of the genotoxicity of methacrylate monomers have been rarely explored. As the polymerization of a monomer is catalyzed by a co-monomer, their combined action should be considered. In the present work, we investigated cytotoxic and genotoxic effects of urethane dimethacrylate (UDMA), often used as a monomer, at 1 mM, and triethylene glycol dimethacrylate (TEGDMA), a typical co-monomer, at 5 mM singly and in combination. Experiments were conducted on Chinese hamster ovary cells. Cell viability, apoptosis and cell cycle were assessed by flow cytometry, whereas DNA damage was evaluated by plasmid conformation test and comet assay. Both compounds decreased the viability of the cells, but did not induce strand breaks in an isolated plasmid DNA. However, both substances, either singly or in combination, damaged DNA in CHO cells as evaluated by comet assay. Both compounds induced apoptosis, but a combined action of them led to a decrease in the number of apoptotic cells. The combined action of UDMA and TEGDMA in the disturbance of cell cycle was lesser compared to the action of each compound individually. Individually, though UDMA and TEGDMA may induce cytotoxic and genotoxic, however, a combination of both does not produce a significant increase in these effects." @default.
• W2015881576 created "2016-06-24" @default.
• W2015881576 creator A5016282083 @default.
• W2015881576 creator A5023441629 @default.
• W2015881576 creator A5038319132 @default.
• W2015881576 creator A5047935455 @default.
• W2015881576 creator A5052186294 @default.
• W2015881576 creator A5053544756 @default.
• W2015881576 creator A5070963991 @default.
• W2015881576 date "2010-12-03" @default.
• W2015881576 modified "2023-10-16" @default.
• W2015881576 title "Independent and combined cytotoxicity and genotoxicity of triethylene glycol dimethacrylate and urethane dimethacrylate" @default.
• W2015881576 cites W1966950219 @default.
• W2015881576 cites W1969176578 @default.
• W2015881576 cites W1971675517 @default.
• W2015881576 cites W1972528079 @default.
• W2015881576 cites W1979786475 @default.
• W2015881576 cites W1981455089 @default.
• W2015881576 cites W1981906810 @default.
• W2015881576 cites W1996682782 @default.
• W2015881576 cites W2012324021 @default.
• W2015881576 cites W2012777147 @default.
• W2015881576 cites W2015500565 @default.
• W2015881576 cites W2018345361 @default.
• W2015881576 cites W2022363046 @default.
• W2015881576 cites W2030560888 @default.
• W2015881576 cites W2035644094 @default.
• W2015881576 cites W2067675728 @default.
• W2015881576 cites W2068808589 @default.
• W2015881576 cites W2075724008 @default.
• W2015881576 cites W2087536710 @default.
• W2015881576 cites W2090168250 @default.
• W2015881576 cites W2090220251 @default.
• W2015881576 cites W2092629964 @default.
• W2015881576 cites W2094426750 @default.
• W2015881576 cites W2105529602 @default.
• W2015881576 cites W2126902508 @default.
• W2015881576 cites W2160569622 @default.
• W2015881576 cites W41480296 @default.
• W2015881576 doi "https://doi.org/10.1007/s11033-010-0593-1" @default.
• W2015881576 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3162630" @default.
• W2015881576 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21127987" @default.
• W2015881576 hasPublicationYear "2010" @default.
• W2015881576 type Work @default.
• W2015881576 sameAs 2015881576 @default.
• W2015881576 citedByCount "51" @default.
• W2015881576 countsByYear W20158815762012 @default.
• W2015881576 countsByYear W20158815762013 @default.
• W2015881576 countsByYear W20158815762014 @default.
• W2015881576 countsByYear W20158815762015 @default.
• W2015881576 countsByYear W20158815762016 @default.
• W2015881576 countsByYear W20158815762017 @default.
• W2015881576 countsByYear W20158815762018 @default.
• W2015881576 countsByYear W20158815762019 @default.
• W2015881576 countsByYear W20158815762020 @default.
• W2015881576 countsByYear W20158815762021 @default.
• W2015881576 countsByYear W20158815762022 @default.
• W2015881576 countsByYear W20158815762023 @default.
• W2015881576 crossrefType "journal-article" @default.
• W2015881576 hasAuthorship W2015881576A5016282083 @default.
• W2015881576 hasAuthorship W2015881576A5023441629 @default.
• W2015881576 hasAuthorship W2015881576A5038319132 @default.
• W2015881576 hasAuthorship W2015881576A5047935455 @default.
• W2015881576 hasAuthorship W2015881576A5052186294 @default.
• W2015881576 hasAuthorship W2015881576A5053544756 @default.
• W2015881576 hasAuthorship W2015881576A5070963991 @default.
• W2015881576 hasBestOaLocation W20158815761 @default.
• W2015881576 hasConcept C109316439 @default.
• W2015881576 hasConcept C12554922 @default.
• W2015881576 hasConcept C132050475 @default.
• W2015881576 hasConcept C143425029 @default.
• W2015881576 hasConcept C166940927 @default.
• W2015881576 hasConcept C178790620 @default.
• W2015881576 hasConcept C185592680 @default.
• W2015881576 hasConcept C188027245 @default.
• W2015881576 hasConcept C190283241 @default.
• W2015881576 hasConcept C202751555 @default.
• W2015881576 hasConcept C2775934670 @default.
• W2015881576 hasConcept C2778959862 @default.
• W2015881576 hasConcept C2780358455 @default.
• W2015881576 hasConcept C29730261 @default.
• W2015881576 hasConcept C44228677 @default.
• W2015881576 hasConcept C521977710 @default.
• W2015881576 hasConcept C53227056 @default.
• W2015881576 hasConcept C552990157 @default.
• W2015881576 hasConcept C55493867 @default.
• W2015881576 hasConcept C86803240 @default.
• W2015881576 hasConceptScore W2015881576C109316439 @default.
• W2015881576 hasConceptScore W2015881576C12554922 @default.
• W2015881576 hasConceptScore W2015881576C132050475 @default.
• W2015881576 hasConceptScore W2015881576C143425029 @default.
• W2015881576 hasConceptScore W2015881576C166940927 @default.
• W2015881576 hasConceptScore W2015881576C178790620 @default.
• W2015881576 hasConceptScore W2015881576C185592680 @default.
• W2015881576 hasConceptScore W2015881576C188027245 @default.
• W2015881576 hasConceptScore W2015881576C190283241 @default.
• W2015881576 hasConceptScore W2015881576C202751555 @default.
• W2015881576 hasConceptScore W2015881576C2775934670 @default.

• next