FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015884551> ?p ?o ?g. }

• W2015884551 endingPage "55" @default.
• W2015884551 startingPage "47" @default.
• W2015884551 abstract "To test the hypothesis that the endogenous opioid system is operative in digitalis arrhythmias, guinea pigs anesthetized with pentothal and breathing spontaneously were allocated to a control group or four naloxone groups: 0.1 mg/kg i.v., 1.0 mg/kg i.v., 2 mg/kg i.v. or 4 mg/kg i.v. after the induction of arrhythmias by digoxin 100 μg/kg i.v. every 15 min. Naloxone at higher doses resulted in a rapid development of fatal arrhythmias with high degree AV block being more frequent than ventricular tachycardiac or fibrillation. Survival was significantly and inversely related to naloxone dose. The role of theautomatic nervous system was studied using cervical cord transection at the C7 level or bilateral cervical vagotomy, or atropine 1.2 mg/kg pretreatment. Cord transection, but not vagotomy, was associated with a significantly higher digoxin dose to produce arrhythmias. Naloxone 4 mg/kg i.v. shortened survival in cord transected animals, but less than in intact animals. Naloxone did not alter survival in vagotomized animals or animals that were pretreated with atropine. Thus, naloxone accelerates the development of fatal cardiac arrhythmias suggesting that endogenous opioids are involved in digitalis toxic arrhythmias an effect interrelated to the autonomic, mainly parasympathetic, nervous system." @default.
• W2015884551 created "2016-06-24" @default.
• W2015884551 creator A5066577966 @default.
• W2015884551 creator A5084294726 @default.
• W2015884551 date "1986-10-01" @default.
• W2015884551 modified "2023-10-16" @default.
• W2015884551 title "Effect of the opiate antagonist naloxone on digitalis induced cardiac arrhythmias" @default.
• W2015884551 cites W1966460769 @default.
• W2015884551 cites W1968422198 @default.
• W2015884551 cites W1990131952 @default.
• W2015884551 cites W1993088841 @default.
• W2015884551 cites W1993577000 @default.
• W2015884551 cites W1994162219 @default.
• W2015884551 cites W1997235155 @default.
• W2015884551 cites W1997428559 @default.
• W2015884551 cites W2006567312 @default.
• W2015884551 cites W2007706248 @default.
• W2015884551 cites W2012461535 @default.
• W2015884551 cites W2023189672 @default.
• W2015884551 cites W2024060499 @default.
• W2015884551 cites W2031403709 @default.
• W2015884551 cites W2040568541 @default.
• W2015884551 cites W2040826653 @default.
• W2015884551 cites W2044579233 @default.
• W2015884551 cites W2050038096 @default.
• W2015884551 cites W2059221416 @default.
• W2015884551 cites W2061939798 @default.
• W2015884551 cites W2064447763 @default.
• W2015884551 cites W2075016390 @default.
• W2015884551 cites W2077017070 @default.
• W2015884551 cites W2081701634 @default.
• W2015884551 cites W2084731209 @default.
• W2015884551 cites W2092899904 @default.
• W2015884551 cites W2118755646 @default.
• W2015884551 cites W2153451664 @default.
• W2015884551 cites W2160527782 @default.
• W2015884551 cites W2165238381 @default.
• W2015884551 cites W2199466998 @default.
• W2015884551 cites W2239875738 @default.
• W2015884551 cites W2241312223 @default.
• W2015884551 cites W2268690767 @default.
• W2015884551 cites W2281699336 @default.
• W2015884551 cites W2314098409 @default.
• W2015884551 cites W2418372079 @default.
• W2015884551 cites W2419061104 @default.
• W2015884551 cites W2470046919 @default.
• W2015884551 cites W2523830041 @default.
• W2015884551 doi "https://doi.org/10.1016/0014-2999(86)90182-2" @default.
• W2015884551 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/3780859" @default.
• W2015884551 hasPublicationYear "1986" @default.
• W2015884551 type Work @default.
• W2015884551 sameAs 2015884551 @default.
• W2015884551 citedByCount "11" @default.
• W2015884551 crossrefType "journal-article" @default.
• W2015884551 hasAuthorship W2015884551A5066577966 @default.
• W2015884551 hasAuthorship W2015884551A5084294726 @default.
• W2015884551 hasConcept C126322002 @default.
• W2015884551 hasConcept C134018914 @default.
• W2015884551 hasConcept C170493617 @default.
• W2015884551 hasConcept C2775859210 @default.
• W2015884551 hasConcept C2776445394 @default.
• W2015884551 hasConcept C2776885963 @default.
• W2015884551 hasConcept C2777372248 @default.
• W2015884551 hasConcept C2777953023 @default.
• W2015884551 hasConcept C2778198053 @default.
• W2015884551 hasConcept C2778720886 @default.
• W2015884551 hasConcept C2778750930 @default.
• W2015884551 hasConcept C2781063702 @default.
• W2015884551 hasConcept C3017995582 @default.
• W2015884551 hasConcept C42219234 @default.
• W2015884551 hasConcept C71924100 @default.
• W2015884551 hasConcept C84393581 @default.
• W2015884551 hasConceptScore W2015884551C126322002 @default.
• W2015884551 hasConceptScore W2015884551C134018914 @default.
• W2015884551 hasConceptScore W2015884551C170493617 @default.
• W2015884551 hasConceptScore W2015884551C2775859210 @default.
• W2015884551 hasConceptScore W2015884551C2776445394 @default.
• W2015884551 hasConceptScore W2015884551C2776885963 @default.
• W2015884551 hasConceptScore W2015884551C2777372248 @default.
• W2015884551 hasConceptScore W2015884551C2777953023 @default.
• W2015884551 hasConceptScore W2015884551C2778198053 @default.
• W2015884551 hasConceptScore W2015884551C2778720886 @default.
• W2015884551 hasConceptScore W2015884551C2778750930 @default.
• W2015884551 hasConceptScore W2015884551C2781063702 @default.
• W2015884551 hasConceptScore W2015884551C3017995582 @default.
• W2015884551 hasConceptScore W2015884551C42219234 @default.
• W2015884551 hasConceptScore W2015884551C71924100 @default.
• W2015884551 hasConceptScore W2015884551C84393581 @default.
• W2015884551 hasIssue "1-2" @default.
• W2015884551 hasLocation W20158845511 @default.
• W2015884551 hasLocation W20158845512 @default.
• W2015884551 hasOpenAccess W2015884551 @default.
• W2015884551 hasPrimaryLocation W20158845511 @default.
• W2015884551 hasRelatedWork W2015884551 @default.
• W2015884551 hasRelatedWork W2032031959 @default.
• W2015884551 hasRelatedWork W2042834119 @default.
• W2015884551 hasRelatedWork W2046613423 @default.
• W2015884551 hasRelatedWork W2065722424 @default.

• next