FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015929853> ?p ?o ?g. }

• W2015929853 abstract "Acute exacerbation of chronic obstructive pulmonary disease (COPD) is defined by modification of the usual COPD symptoms, dyspnea, coughing and sputum, beyond daily variations, with a sudden onset, and requiring modification of the usual treatment. Exacerbations stud the course of COPD. Their frequency is variable, averaging 1-2 per year. Their frequency generally increases with COPD severity. Exacerbations impair patients' quality of life and aggravate disease prognosis by accelerating the decline in FEV1, the primary indicator of respiratory function. The most frequent causes of exacerbations are viral and bacterial respiratory infections and pollution. No cause is identified for nearly one third of all exacerbations. Most exacerbations can be treated at home, if a careful search for signs of clinical severity is negative. Treatment combines inhaled bronchodilator agents (beta-2 agonists, combined if necessary with anticholinergics) and oral corticosteroid therapy (prednisone: 0.5 mg/kg/d for 1 week) when the COPD is severe or signs of severity accompany the exacerbation. Antibiotic therapy is justified when the sputum appears purulent. Severe exacerbation may require oxygen therapy in cases of severe hypoxemia (PaO(2)<60 mm Hg) or mechanically assisted ventilation, essentially by noninvasive ventilation in cases of respiratory acidosis (pH<7.35). Noninvasive ventilation improves dyspnea and respiratory acidosis, diminishes respiratory frequency, intubation, duration of hospitalization, nosocomial infections, and mortality. Pulmonary follow-up is necessary after an exacerbation, especially to prevent the recurrence of exacerbations by measures that have been demonstrated to be effective, including help in smoking cessation, adaptation of COPD treatment, vaccination against influenza and pneumonia (pneumococci), and respiratory rehabilitation. Early diagnosis and rapid treatment of exacerbations can limit their impact, improve quality of life, and reduce the risk of hospitalization." @default.
• W2015929853 created "2016-06-24" @default.
• W2015929853 creator A5016839791 @default.
• W2015929853 creator A5021163774 @default.
• W2015929853 creator A5030999203 @default.
• W2015929853 creator A5033486063 @default.
• W2015929853 creator A5089290794 @default.
• W2015929853 date "2009-03-01" @default.
• W2015929853 modified "2023-09-29" @default.
• W2015929853 title "Exacerbations de bronchopneumopathie chronique obstructive" @default.
• W2015929853 cites W1483163361 @default.
• W2015929853 cites W1973530626 @default.
• W2015929853 cites W1973667216 @default.
• W2015929853 cites W1973742535 @default.
• W2015929853 cites W1987555297 @default.
• W2015929853 cites W1988645485 @default.
• W2015929853 cites W1991648511 @default.
• W2015929853 cites W1993049151 @default.
• W2015929853 cites W2010760854 @default.
• W2015929853 cites W2010967671 @default.
• W2015929853 cites W2012519534 @default.
• W2015929853 cites W2034292816 @default.
• W2015929853 cites W2061693875 @default.
• W2015929853 cites W2066161938 @default.
• W2015929853 cites W2068750795 @default.
• W2015929853 cites W2098115046 @default.
• W2015929853 cites W2104636056 @default.
• W2015929853 cites W2106060515 @default.
• W2015929853 cites W2108600759 @default.
• W2015929853 cites W2110947112 @default.
• W2015929853 cites W2111156631 @default.
• W2015929853 cites W2112162293 @default.
• W2015929853 cites W2116784557 @default.
• W2015929853 cites W2117837864 @default.
• W2015929853 cites W2122004939 @default.
• W2015929853 cites W2122790962 @default.
• W2015929853 cites W2127951128 @default.
• W2015929853 cites W2137969357 @default.
• W2015929853 cites W2141034778 @default.
• W2015929853 cites W2142724633 @default.
• W2015929853 cites W2149296107 @default.
• W2015929853 cites W2149863487 @default.
• W2015929853 cites W2157070216 @default.
• W2015929853 cites W2160488228 @default.
• W2015929853 cites W2162360797 @default.
• W2015929853 cites W2163870873 @default.
• W2015929853 cites W2166432084 @default.
• W2015929853 cites W2473808969 @default.
• W2015929853 cites W2906923342 @default.
• W2015929853 cites W69630261 @default.
• W2015929853 doi "https://doi.org/10.1016/j.lpm.2008.12.014" @default.
• W2015929853 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19185446" @default.
• W2015929853 hasPublicationYear "2009" @default.
• W2015929853 type Work @default.
• W2015929853 sameAs 2015929853 @default.
• W2015929853 citedByCount "12" @default.
• W2015929853 countsByYear W20159298532012 @default.
• W2015929853 countsByYear W20159298532013 @default.
• W2015929853 countsByYear W20159298532014 @default.
• W2015929853 countsByYear W20159298532015 @default.
• W2015929853 countsByYear W20159298532016 @default.
• W2015929853 countsByYear W20159298532020 @default.
• W2015929853 crossrefType "journal-article" @default.
• W2015929853 hasAuthorship W2015929853A5016839791 @default.
• W2015929853 hasAuthorship W2015929853A5021163774 @default.
• W2015929853 hasAuthorship W2015929853A5030999203 @default.
• W2015929853 hasAuthorship W2015929853A5033486063 @default.
• W2015929853 hasAuthorship W2015929853A5089290794 @default.
• W2015929853 hasConcept C126322002 @default.
• W2015929853 hasConcept C142724271 @default.
• W2015929853 hasConcept C177713679 @default.
• W2015929853 hasConcept C2776042228 @default.
• W2015929853 hasConcept C2776301714 @default.
• W2015929853 hasConcept C2776780178 @default.
• W2015929853 hasConcept C2776989520 @default.
• W2015929853 hasConcept C2777014857 @default.
• W2015929853 hasConcept C2780630273 @default.
• W2015929853 hasConcept C2781018748 @default.
• W2015929853 hasConcept C2781069245 @default.
• W2015929853 hasConcept C534529494 @default.
• W2015929853 hasConcept C71924100 @default.
• W2015929853 hasConceptScore W2015929853C126322002 @default.
• W2015929853 hasConceptScore W2015929853C142724271 @default.
• W2015929853 hasConceptScore W2015929853C177713679 @default.
• W2015929853 hasConceptScore W2015929853C2776042228 @default.
• W2015929853 hasConceptScore W2015929853C2776301714 @default.
• W2015929853 hasConceptScore W2015929853C2776780178 @default.
• W2015929853 hasConceptScore W2015929853C2776989520 @default.
• W2015929853 hasConceptScore W2015929853C2777014857 @default.
• W2015929853 hasConceptScore W2015929853C2780630273 @default.
• W2015929853 hasConceptScore W2015929853C2781018748 @default.
• W2015929853 hasConceptScore W2015929853C2781069245 @default.
• W2015929853 hasConceptScore W2015929853C534529494 @default.
• W2015929853 hasConceptScore W2015929853C71924100 @default.
• W2015929853 hasLocation W20159298531 @default.
• W2015929853 hasLocation W20159298532 @default.
• W2015929853 hasOpenAccess W2015929853 @default.
• W2015929853 hasPrimaryLocation W20159298531 @default.
• W2015929853 isParatext "false" @default.
• W2015929853 isRetracted "false" @default.

• next