FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015938431> ?p ?o ?g. }

• W2015938431 endingPage "180" @default.
• W2015938431 startingPage "172" @default.
• W2015938431 abstract "Adipose tissue-derived stem cells (ADSC) are isolated from the stromal vascular fraction (SVF) of adipose tissue and considered an excellent cell source for regenerative medicine. During the isolation and propagation of several human ADSC cell lines, we observed the emergence of an unusual cell line designated HADSC-6. Although initially fibroblast-like as typical ADSC are, HADSC-6 cells became homogeneously cuboid in shape, had very little cytoplasm, and formed aggregates with capsule-like boundary. Proliferation assay showed that HADSC-6 grew much faster than typical HADSC cell lines, such as HADSC-20. Immunocytochemistry showed that HADSC-6 did not express endothelial markers CD31 and vWF, and matrigel tube formation assay showed that it was unable to form endothelial-like tube structures. However, LDL uptake, a reliable endothelial marker, was positively identified. Chromosomal analysis showed that HADSC-6 cells were hypertriploid, and soft agar colony formation assay showed that they were able to proliferate and form large colonies in an anchorage-independent manner. However, tumorigenicity test showed that HADSC-6 was unable to form tumors in athymic mice. RT-PCR analysis showed that both HADSC-6 and HADSC-20 expressed VEGF-A, VEGF-B, VEGF-D, and VEGFR1 but not VEGFR2 or VEGFR3. VEGF-C, however, was expressed at a high level in HADSC-20 but undetectable in HADSC-6. In the IGF system, IGF-1 was abundantly expressed in HADSC-20 but marginally detectable in HADSC-6, and IGF-1R was abundantly expressed in HADSC-6 but not detectable in HADSC-20. In the FGF system, bFGF was abundantly expressed in HADSC-20 but marginally detectable in HADSC-6, and FGFR1 was abundantly expressed in both. Taken together, these results suggested that HADSC-6 cells were spontaneously transformed from the endothelium; therefore, they were further compared to previously published data of four naturally occurring human angiosarcoma cell lines. The results showed that the established angiosarcoma cell lines exhibit considerable variations among themselves and HADSC-6 displayed most of these variable characteristics." @default.
• W2015938431 created "2016-06-24" @default.
• W2015938431 creator A5036422573 @default.
• W2015938431 creator A5054667123 @default.
• W2015938431 creator A5058637832 @default.
• W2015938431 creator A5073632783 @default.
• W2015938431 creator A5081192418 @default.
• W2015938431 creator A5090856147 @default.
• W2015938431 creator A5091637974 @default.
• W2015938431 date "2009-02-01" @default.
• W2015938431 modified "2023-10-18" @default.
• W2015938431 title "Identification of an aberrant cell line among human adipose tissue-derived stem cell isolates" @default.
• W2015938431 cites W1987643476 @default.
• W2015938431 cites W1996252991 @default.
• W2015938431 cites W2015947716 @default.
• W2015938431 cites W2020910894 @default.
• W2015938431 cites W2027015392 @default.
• W2015938431 cites W2049584490 @default.
• W2015938431 cites W2054178500 @default.
• W2015938431 cites W2068852777 @default.
• W2015938431 cites W2069810199 @default.
• W2015938431 cites W2072265495 @default.
• W2015938431 cites W2086980194 @default.
• W2015938431 cites W2088059131 @default.
• W2015938431 cites W2091130756 @default.
• W2015938431 cites W2095085916 @default.
• W2015938431 cites W2100221605 @default.
• W2015938431 cites W2115062578 @default.
• W2015938431 cites W2118272397 @default.
• W2015938431 cites W2124857894 @default.
• W2015938431 cites W2149996379 @default.
• W2015938431 cites W2173497140 @default.
• W2015938431 cites W2500285417 @default.
• W2015938431 cites W4242016168 @default.
• W2015938431 doi "https://doi.org/10.1016/j.diff.2008.09.019" @default.
• W2015938431 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2893016" @default.
• W2015938431 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19281777" @default.
• W2015938431 hasPublicationYear "2009" @default.
• W2015938431 type Work @default.
• W2015938431 sameAs 2015938431 @default.
• W2015938431 citedByCount "32" @default.
• W2015938431 countsByYear W20159384312012 @default.
• W2015938431 countsByYear W20159384312013 @default.
• W2015938431 countsByYear W20159384312014 @default.
• W2015938431 countsByYear W20159384312015 @default.
• W2015938431 countsByYear W20159384312016 @default.
• W2015938431 countsByYear W20159384312017 @default.
• W2015938431 countsByYear W20159384312018 @default.
• W2015938431 countsByYear W20159384312019 @default.
• W2015938431 countsByYear W20159384312020 @default.
• W2015938431 countsByYear W20159384312021 @default.
• W2015938431 countsByYear W20159384312022 @default.
• W2015938431 countsByYear W20159384312023 @default.
• W2015938431 crossrefType "journal-article" @default.
• W2015938431 hasAuthorship W2015938431A5036422573 @default.
• W2015938431 hasAuthorship W2015938431A5054667123 @default.
• W2015938431 hasAuthorship W2015938431A5058637832 @default.
• W2015938431 hasAuthorship W2015938431A5073632783 @default.
• W2015938431 hasAuthorship W2015938431A5081192418 @default.
• W2015938431 hasAuthorship W2015938431A5090856147 @default.
• W2015938431 hasAuthorship W2015938431A5091637974 @default.
• W2015938431 hasBestOaLocation W20159384312 @default.
• W2015938431 hasConcept C134018914 @default.
• W2015938431 hasConcept C142724271 @default.
• W2015938431 hasConcept C153911025 @default.
• W2015938431 hasConcept C171089720 @default.
• W2015938431 hasConcept C2778608917 @default.
• W2015938431 hasConcept C28328180 @default.
• W2015938431 hasConcept C54355233 @default.
• W2015938431 hasConcept C71924100 @default.
• W2015938431 hasConcept C81885089 @default.
• W2015938431 hasConcept C86803240 @default.
• W2015938431 hasConcept C95444343 @default.
• W2015938431 hasConceptScore W2015938431C134018914 @default.
• W2015938431 hasConceptScore W2015938431C142724271 @default.
• W2015938431 hasConceptScore W2015938431C153911025 @default.
• W2015938431 hasConceptScore W2015938431C171089720 @default.
• W2015938431 hasConceptScore W2015938431C2778608917 @default.
• W2015938431 hasConceptScore W2015938431C28328180 @default.
• W2015938431 hasConceptScore W2015938431C54355233 @default.
• W2015938431 hasConceptScore W2015938431C71924100 @default.
• W2015938431 hasConceptScore W2015938431C81885089 @default.
• W2015938431 hasConceptScore W2015938431C86803240 @default.
• W2015938431 hasConceptScore W2015938431C95444343 @default.
• W2015938431 hasIssue "2" @default.
• W2015938431 hasLocation W20159384311 @default.
• W2015938431 hasLocation W20159384312 @default.
• W2015938431 hasLocation W20159384313 @default.
• W2015938431 hasLocation W20159384314 @default.
• W2015938431 hasOpenAccess W2015938431 @default.
• W2015938431 hasPrimaryLocation W20159384311 @default.
• W2015938431 hasRelatedWork W1980546969 @default.
• W2015938431 hasRelatedWork W2018736243 @default.
• W2015938431 hasRelatedWork W2045469574 @default.
• W2015938431 hasRelatedWork W2056434117 @default.
• W2015938431 hasRelatedWork W2084245009 @default.
• W2015938431 hasRelatedWork W2090264742 @default.
• W2015938431 hasRelatedWork W3005804680 @default.

• next