FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2015952005> ?p ?o ?g. }

• W2015952005 endingPage "347" @default.
• W2015952005 startingPage "335" @default.
• W2015952005 abstract "Types and projections of neurons that received cholinergic, purinergic and other fast excitatory synaptic inputs in myenteric ganglia of the guinea-pig distal colon were identified using combined electrophysiological recording, application of selective antagonists, marker dye filling via the recording microelectrode, and immunohistochemical characterisation. Fast synaptic inputs were recorded from all major subtypes of uniaxonal neurons including Dogiel type I neurons, filamentous interneurons, circular muscle motor neurons and longitudinal muscle motor neurons. Fast excitatory postsynaptic potentials were completely blocked by the nicotinic receptor antagonists hexamethonium or mecamylamine in 62% of neurons tested and were partially inhibited in the remaining neurons. The P2 purine receptor antagonist, pyridoxal-phosphate-6-azophenyl-2',4'-disulfonic acid, reduced the amplitudes of fast excitatory postsynaptic potentials in 20% of myenteric neurons. The 5-hydroxytryptamine(3) receptor antagonist granisetron reduced the amplitude of fast excitatory postsynaptic potentials in only one of 15 neurons tested. In five of five neurons tested, the combination of a nicotinic antagonist, pyridoxal-phosphate-6-azophenyl-2',4'-disulfonic acid, granisetron and 6-cyano-7-nitroquinoxaline-2,3-dione did not completely block the fast excitatory postsynaptic potentials. Immunohistochemical studies of the neurons that had been identified electrophysiologically and morphologically imply that P2X(2) receptors may mediate fast transmission in some neurons, and that other P2X receptor subtypes may also be involved in fast synaptic transmission to myenteric neurons of the guinea-pig distal colon. Neurons with nicotinic and pyridoxal-phosphate-6-azophenyl-2',4'-disulfonic acid-sensitive fast excitatory postsynaptic potentials were present in both ascending and descending pathways in the distal colon. Thus, neither cholinergic nor mixed cholinergic/purinergic synaptic responses are confined to a particular class of neuron. The results indicate that acetylcholine and ATP are the major fast excitatory neurotransmitters in guinea-pig distal colon myenteric ganglia." @default.
• W2015952005 created "2016-06-24" @default.
• W2015952005 creator A5060226120 @default.
• W2015952005 creator A5076471787 @default.
• W2015952005 creator A5083520924 @default.
• W2015952005 date "2003-01-01" @default.
• W2015952005 modified "2023-10-14" @default.
• W2015952005 title "Analysis of purinergic and cholinergic fast synaptic transmission to identified myenteric neurons" @default.
• W2015952005 cites W1505595392 @default.
• W2015952005 cites W1592755942 @default.
• W2015952005 cites W1775244163 @default.
• W2015952005 cites W1964157347 @default.
• W2015952005 cites W1966755187 @default.
• W2015952005 cites W1966988326 @default.
• W2015952005 cites W1974260260 @default.
• W2015952005 cites W1976984992 @default.
• W2015952005 cites W1990736267 @default.
• W2015952005 cites W1992965467 @default.
• W2015952005 cites W1997363796 @default.
• W2015952005 cites W2007964531 @default.
• W2015952005 cites W2008808395 @default.
• W2015952005 cites W2009046255 @default.
• W2015952005 cites W2031694081 @default.
• W2015952005 cites W2033229260 @default.
• W2015952005 cites W2037487755 @default.
• W2015952005 cites W2039824257 @default.
• W2015952005 cites W2042169787 @default.
• W2015952005 cites W2042358571 @default.
• W2015952005 cites W2043127838 @default.
• W2015952005 cites W2043520799 @default.
• W2015952005 cites W2049267497 @default.
• W2015952005 cites W2049760814 @default.
• W2015952005 cites W2058585578 @default.
• W2015952005 cites W2063601395 @default.
• W2015952005 cites W2067894223 @default.
• W2015952005 cites W2071633080 @default.
• W2015952005 cites W2074385581 @default.
• W2015952005 cites W2078898236 @default.
• W2015952005 cites W2089283816 @default.
• W2015952005 cites W2089465925 @default.
• W2015952005 cites W2095139743 @default.
• W2015952005 cites W2112867279 @default.
• W2015952005 cites W2114926262 @default.
• W2015952005 cites W2115372707 @default.
• W2015952005 cites W2115609883 @default.
• W2015952005 cites W2140327830 @default.
• W2015952005 cites W2140341287 @default.
• W2015952005 cites W2143275674 @default.
• W2015952005 cites W2143486366 @default.
• W2015952005 cites W2172228212 @default.
• W2015952005 cites W4244333876 @default.
• W2015952005 doi "https://doi.org/10.1016/s0306-4522(02)00749-2" @default.
• W2015952005 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12559090" @default.
• W2015952005 hasPublicationYear "2003" @default.
• W2015952005 type Work @default.
• W2015952005 sameAs 2015952005 @default.
• W2015952005 citedByCount "59" @default.
• W2015952005 countsByYear W20159520052012 @default.
• W2015952005 countsByYear W20159520052013 @default.
• W2015952005 countsByYear W20159520052014 @default.
• W2015952005 countsByYear W20159520052015 @default.
• W2015952005 countsByYear W20159520052017 @default.
• W2015952005 countsByYear W20159520052018 @default.
• W2015952005 countsByYear W20159520052019 @default.
• W2015952005 countsByYear W20159520052021 @default.
• W2015952005 countsByYear W20159520052022 @default.
• W2015952005 crossrefType "journal-article" @default.
• W2015952005 hasAuthorship W2015952005A5060226120 @default.
• W2015952005 hasAuthorship W2015952005A5076471787 @default.
• W2015952005 hasAuthorship W2015952005A5083520924 @default.
• W2015952005 hasConcept C112592302 @default.
• W2015952005 hasConcept C134018914 @default.
• W2015952005 hasConcept C169760540 @default.
• W2015952005 hasConcept C170493617 @default.
• W2015952005 hasConcept C17077164 @default.
• W2015952005 hasConcept C185592680 @default.
• W2015952005 hasConcept C188987157 @default.
• W2015952005 hasConcept C197341189 @default.
• W2015952005 hasConcept C200170125 @default.
• W2015952005 hasConcept C22885893 @default.
• W2015952005 hasConcept C2776991684 @default.
• W2015952005 hasConcept C2780019924 @default.
• W2015952005 hasConcept C55493867 @default.
• W2015952005 hasConcept C57306754 @default.
• W2015952005 hasConcept C86803240 @default.
• W2015952005 hasConceptScore W2015952005C112592302 @default.
• W2015952005 hasConceptScore W2015952005C134018914 @default.
• W2015952005 hasConceptScore W2015952005C169760540 @default.
• W2015952005 hasConceptScore W2015952005C170493617 @default.
• W2015952005 hasConceptScore W2015952005C17077164 @default.
• W2015952005 hasConceptScore W2015952005C185592680 @default.
• W2015952005 hasConceptScore W2015952005C188987157 @default.
• W2015952005 hasConceptScore W2015952005C197341189 @default.
• W2015952005 hasConceptScore W2015952005C200170125 @default.
• W2015952005 hasConceptScore W2015952005C22885893 @default.
• W2015952005 hasConceptScore W2015952005C2776991684 @default.
• W2015952005 hasConceptScore W2015952005C2780019924 @default.
• W2015952005 hasConceptScore W2015952005C55493867 @default.

• next