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- W2015962989 abstract "Summary: The feasibility of using nonradioactive heterologous serum albumin measured by rocket immunoelectrophoresis as tracer for plasma volume measurements was evaluated by comparing simultaneous distribution volumes and plasma half-lives (t1/2) of human serum albumin (HSA) and Evans blue dye (T1824) in a group of conscious rats. The animals were studied under normal water intake and after a 48-h period of water deprivation. The kinetic behavior in plasma was qualitatively similar for both tracers, but T1824 distributed beyond the HSA space and had half-lives in plasma lower than those of HSA. Water deprivation induced a 14% decrease in the HSA space, from 2.7 ± 0.1 to 2.4 ± 0.2 ml/100 g body weight. We conclude that serum albumin spaces measured immunoelectrophoretically are a better reflection of true plasma volume than T1824 spaces and can be used advantageously in determinations of plasma volume." @default.
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- W2015962989 title "Heterologous Serum Albumin as Tracer for Plasma Volume Measurements Evaluated in Conscious Nondehydrated and 48-Hour Water-Deprived Rats" @default.
- W2015962989 doi "https://doi.org/10.1097/00005344-198904000-00013" @default.
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