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• W2015982332 abstract "Nuclear localization has been observed for glycolytic enzymes but not for key gluconeogenic enzymes. We report our findings on the intracellular localization of liver FBPase in rat liver and kidney, the main organs in the endogenous glucose production. Immunofluorescence and confocal analysis revealed that FBPase was present in the cytosol and, unexpectedly, inside the nucleus of hepatocytes and proximal cells of the nephron. Additionally, FBPase was found in the plasma membrane area of adjacent hepatocytes where glycogen is synthesized and in the apical region of proximal kidney cells. This subcellular distribution in multiple compartments suggests the presence of different localization signals on FBPase for diverse metabolic functions." @default.
• W2015982332 created "2016-06-24" @default.
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• W2015982332 date "2003-07-29" @default.
• W2015982332 modified "2023-09-26" @default.
• W2015982332 title "Nuclear localization of liver FBPase isoenzyme in kidney and liver" @default.
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• W2015982332 doi "https://doi.org/10.1016/s0014-5793(03)00809-3" @default.
• W2015982332 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12935882" @default.
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