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- W2015993876 abstract "Diffusion potentials for Na+, Cl-, acetate (Ac−), propionate (Pr−) and butyrate (Bu-) across the isolated epithelium of the proximal and the distal colon of guinea−pig were measured with flowing electrodes in Ussing chambers. Permeabilities of the anions are expressed in relation to the permeability of sodium. Unidirectional fluxes of Na+ and short-chain fatty acids (SCFAs) were estimated. Fluxes of SCFA anions and of undissociated SCFAs were calculated from relative permeabilities and flux values. In the proximal colon of guinea-pig 50% of SCFAs were transported in the dissociated and 50% in the undissociated form; transport rates of the three SCFAs were similar. In the distal colon SCFA transport was based primarily on diffusion of the free acids; the ratios of fluxes were: HAc/Ac- = 2·4; HPr/Pr− = 6·9; HBu/Bu− = 9·3, and transport rates increased with chain length of the SCFA." @default.
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- W2015993876 date "1989-07-10" @default.
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- W2015993876 title "ABSORPTION OF DISSOCIATED AND UNDISSOCIATED SHORT-CHAIN FATTY ACIDS ACROSS THE COLONIC EPITHELIUM OF GUINEA-PIG" @default.
- W2015993876 doi "https://doi.org/10.1113/expphysiol.1989.sp003298" @default.
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