FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016017842> ?p ?o ?g. }

• W2016017842 endingPage "351" @default.
• W2016017842 startingPage "348" @default.
• W2016017842 abstract "The aim of this study was to test the hypothesis that closely related human leukocyte antigen (HLA) haplotypes containing the DRB1*07:01 gene [‘DR7’ (DRB1*07:01-DQA1*02:01-DQB1*02:01g or DRB1*07:01-DQA1*03:01-DQB1*02:01g) haplotypes] derived from European and African populations differ in their genetic susceptibility for type 1 diabetes (T1D) depending on the DQ-α molecule present. A combined total of 98 African American T1D patients from the Type 1 Diabetes Genetics Consortium and from Children's Hospital and Research Center Oakland were genotyped for the HLA class II loci DRB1, DQA1, and DQB1. DNA samples extracted from newborn blood spot cards from African Americans born in California (n = 947) were used as a population-based control group. Among African American cases, the European-derived DRB1*07:01-DQA1*02:01-DQB1*02:01g haplotype was protective for T1D risk (odds ratio (OR) = 0.34; 95% confidence interval (CI) 0.14–0.78; P < 0.011), but the African-derived DRB1*07:01-DQA1*03:01-DQB1*02:01g haplotype increased T1D risk (OR = 3.96; 95% CI 1.94–8.08; P < 5.5E-05). The effect of DRB1*07:01-DQB1*02:01g on T1D susceptibility depends on the DQA1 allele. DRB1*07:01-DQA1*02:01-DQB1*02:01g is protective for T1D; however, the presence of DQA1*03:01 on the DRB1*07:01-DQB1*02:01g haplotype not only renders the DR7 haplotype not protective but also creates a haplotype with significant T1D risk. These data underscore the importance of assessing genetic effects within ethnic context." @default.
• W2016017842 created "2016-06-24" @default.
• W2016017842 creator A5021482151 @default.
• W2016017842 creator A5029096313 @default.
• W2016017842 creator A5032894321 @default.
• W2016017842 creator A5046569059 @default.
• W2016017842 date "2011-10-11" @default.
• W2016017842 modified "2023-10-18" @default.
• W2016017842 title "Race-specific type 1 diabetes risk of HLA-DR7 haplotypes" @default.
• W2016017842 cites W2024108088 @default.
• W2016017842 cites W2079490247 @default.
• W2016017842 cites W2094090790 @default.
• W2016017842 cites W2094737836 @default.
• W2016017842 cites W2095720372 @default.
• W2016017842 cites W2101070171 @default.
• W2016017842 cites W2110458118 @default.
• W2016017842 cites W2115140269 @default.
• W2016017842 cites W2145527041 @default.
• W2016017842 cites W2157754662 @default.
• W2016017842 doi "https://doi.org/10.1111/j.1399-0039.2011.01772.x" @default.
• W2016017842 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3193161" @default.
• W2016017842 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/21988721" @default.
• W2016017842 hasPublicationYear "2011" @default.
• W2016017842 type Work @default.
• W2016017842 sameAs 2016017842 @default.
• W2016017842 citedByCount "18" @default.
• W2016017842 countsByYear W20160178422012 @default.
• W2016017842 countsByYear W20160178422013 @default.
• W2016017842 countsByYear W20160178422014 @default.
• W2016017842 countsByYear W20160178422015 @default.
• W2016017842 countsByYear W20160178422016 @default.
• W2016017842 countsByYear W20160178422018 @default.
• W2016017842 countsByYear W20160178422019 @default.
• W2016017842 countsByYear W20160178422020 @default.
• W2016017842 countsByYear W20160178422022 @default.
• W2016017842 crossrefType "journal-article" @default.
• W2016017842 hasAuthorship W2016017842A5021482151 @default.
• W2016017842 hasAuthorship W2016017842A5029096313 @default.
• W2016017842 hasAuthorship W2016017842A5032894321 @default.
• W2016017842 hasAuthorship W2016017842A5046569059 @default.
• W2016017842 hasBestOaLocation W20160178422 @default.
• W2016017842 hasConcept C104317684 @default.
• W2016017842 hasConcept C126322002 @default.
• W2016017842 hasConcept C134018914 @default.
• W2016017842 hasConcept C144024400 @default.
• W2016017842 hasConcept C147483822 @default.
• W2016017842 hasConcept C149923435 @default.
• W2016017842 hasConcept C156957248 @default.
• W2016017842 hasConcept C180754005 @default.
• W2016017842 hasConcept C188280979 @default.
• W2016017842 hasConcept C197754878 @default.
• W2016017842 hasConcept C203014093 @default.
• W2016017842 hasConcept C2775983672 @default.
• W2016017842 hasConcept C2779910283 @default.
• W2016017842 hasConcept C2781232474 @default.
• W2016017842 hasConcept C2908647359 @default.
• W2016017842 hasConcept C54355233 @default.
• W2016017842 hasConcept C555293320 @default.
• W2016017842 hasConcept C59822182 @default.
• W2016017842 hasConcept C71924100 @default.
• W2016017842 hasConcept C76509639 @default.
• W2016017842 hasConcept C86803240 @default.
• W2016017842 hasConceptScore W2016017842C104317684 @default.
• W2016017842 hasConceptScore W2016017842C126322002 @default.
• W2016017842 hasConceptScore W2016017842C134018914 @default.
• W2016017842 hasConceptScore W2016017842C144024400 @default.
• W2016017842 hasConceptScore W2016017842C147483822 @default.
• W2016017842 hasConceptScore W2016017842C149923435 @default.
• W2016017842 hasConceptScore W2016017842C156957248 @default.
• W2016017842 hasConceptScore W2016017842C180754005 @default.
• W2016017842 hasConceptScore W2016017842C188280979 @default.
• W2016017842 hasConceptScore W2016017842C197754878 @default.
• W2016017842 hasConceptScore W2016017842C203014093 @default.
• W2016017842 hasConceptScore W2016017842C2775983672 @default.
• W2016017842 hasConceptScore W2016017842C2779910283 @default.
• W2016017842 hasConceptScore W2016017842C2781232474 @default.
• W2016017842 hasConceptScore W2016017842C2908647359 @default.
• W2016017842 hasConceptScore W2016017842C54355233 @default.
• W2016017842 hasConceptScore W2016017842C555293320 @default.
• W2016017842 hasConceptScore W2016017842C59822182 @default.
• W2016017842 hasConceptScore W2016017842C71924100 @default.
• W2016017842 hasConceptScore W2016017842C76509639 @default.
• W2016017842 hasConceptScore W2016017842C86803240 @default.
• W2016017842 hasIssue "5" @default.
• W2016017842 hasLocation W20160178421 @default.
• W2016017842 hasLocation W20160178422 @default.
• W2016017842 hasLocation W20160178423 @default.
• W2016017842 hasLocation W20160178424 @default.
• W2016017842 hasOpenAccess W2016017842 @default.
• W2016017842 hasPrimaryLocation W20160178421 @default.
• W2016017842 hasRelatedWork W1533701456 @default.
• W2016017842 hasRelatedWork W1977873497 @default.
• W2016017842 hasRelatedWork W1991727705 @default.
• W2016017842 hasRelatedWork W201555586 @default.
• W2016017842 hasRelatedWork W2040852100 @default.
• W2016017842 hasRelatedWork W2050756521 @default.
• W2016017842 hasRelatedWork W2064435204 @default.
• W2016017842 hasRelatedWork W2108369798 @default.

• next