Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016022093> ?p ?o ?g. }
Showing items 1 to 91 of
91
with 100 items per page.
- W2016022093 endingPage "83" @default.
- W2016022093 startingPage "76" @default.
- W2016022093 abstract "Graft-versus-host disease (GVHD) is known to cause profound dysregulation of the immune system, although its effector mechanisms are not fully understood. In this study, we investigated what factors influenced the development of GVHD. BALB/c nude mice (H-2d) injected with MHC-disparate B6(H-2b) spleen cells exhibited transient GVHD such as hunched back, diarrhea, loss of body weight and splenomegaly. No animals died during the period of observation. BALB/c nude mice produced alloantibodies to the donor cells. The injection of the serum from GVHD nude mice into naive nude mice can protect from GVHD. Donor derived H-2b+ cells were recognized in the recipient lymph nodes and skin. Prevention of GVHD was achieved by the pretreatment of spleen cells with anti-Thy-1.2 antibody or anti-CD4 antibody and complement, while it was not done by the pretreatment of spleen cells with anti-CD8 antibody and complement. These data demonstrate that Thy-1.2+ CD4+ CD8- lymphocytes are important effector cells and alloantibodies to the donor cells prevent GVHD in this model." @default.
- W2016022093 created "2016-06-24" @default.
- W2016022093 creator A5000293883 @default.
- W2016022093 creator A5074376385 @default.
- W2016022093 creator A5087343660 @default.
- W2016022093 date "1996-01-01" @default.
- W2016022093 modified "2023-10-01" @default.
- W2016022093 title "Studies on transient graft-versus-host disease in BALB/c nude mice injected with allogeneic C57BL/6 splenocytes" @default.
- W2016022093 cites W1432114414 @default.
- W2016022093 cites W1587628687 @default.
- W2016022093 cites W1898571595 @default.
- W2016022093 cites W1910186784 @default.
- W2016022093 cites W1975303153 @default.
- W2016022093 cites W1997378038 @default.
- W2016022093 cites W2017335997 @default.
- W2016022093 cites W2025100795 @default.
- W2016022093 cites W2029303244 @default.
- W2016022093 cites W2032549221 @default.
- W2016022093 cites W2065900213 @default.
- W2016022093 cites W2077611645 @default.
- W2016022093 cites W2081547480 @default.
- W2016022093 cites W2081913714 @default.
- W2016022093 cites W2085910259 @default.
- W2016022093 cites W2089121863 @default.
- W2016022093 cites W2094292853 @default.
- W2016022093 cites W2095029406 @default.
- W2016022093 cites W2096648897 @default.
- W2016022093 cites W2127761554 @default.
- W2016022093 cites W2135241061 @default.
- W2016022093 cites W2327528857 @default.
- W2016022093 cites W2395135053 @default.
- W2016022093 cites W2404611980 @default.
- W2016022093 cites W2408586029 @default.
- W2016022093 cites W2415106997 @default.
- W2016022093 cites W249803208 @default.
- W2016022093 cites W63985575 @default.
- W2016022093 doi "https://doi.org/10.1016/0923-1811(95)00423-8" @default.
- W2016022093 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/8867771" @default.
- W2016022093 hasPublicationYear "1996" @default.
- W2016022093 type Work @default.
- W2016022093 sameAs 2016022093 @default.
- W2016022093 citedByCount "2" @default.
- W2016022093 countsByYear W20160220932016 @default.
- W2016022093 crossrefType "journal-article" @default.
- W2016022093 hasAuthorship W2016022093A5000293883 @default.
- W2016022093 hasAuthorship W2016022093A5074376385 @default.
- W2016022093 hasAuthorship W2016022093A5087343660 @default.
- W2016022093 hasConcept C126322002 @default.
- W2016022093 hasConcept C159654299 @default.
- W2016022093 hasConcept C167672396 @default.
- W2016022093 hasConcept C189976730 @default.
- W2016022093 hasConcept C203014093 @default.
- W2016022093 hasConcept C207936829 @default.
- W2016022093 hasConcept C2779972918 @default.
- W2016022093 hasConcept C2780931953 @default.
- W2016022093 hasConcept C2911091166 @default.
- W2016022093 hasConcept C71924100 @default.
- W2016022093 hasConcept C8891405 @default.
- W2016022093 hasConceptScore W2016022093C126322002 @default.
- W2016022093 hasConceptScore W2016022093C159654299 @default.
- W2016022093 hasConceptScore W2016022093C167672396 @default.
- W2016022093 hasConceptScore W2016022093C189976730 @default.
- W2016022093 hasConceptScore W2016022093C203014093 @default.
- W2016022093 hasConceptScore W2016022093C207936829 @default.
- W2016022093 hasConceptScore W2016022093C2779972918 @default.
- W2016022093 hasConceptScore W2016022093C2780931953 @default.
- W2016022093 hasConceptScore W2016022093C2911091166 @default.
- W2016022093 hasConceptScore W2016022093C71924100 @default.
- W2016022093 hasConceptScore W2016022093C8891405 @default.
- W2016022093 hasIssue "1" @default.
- W2016022093 hasLocation W20160220931 @default.
- W2016022093 hasLocation W20160220932 @default.
- W2016022093 hasOpenAccess W2016022093 @default.
- W2016022093 hasPrimaryLocation W20160220931 @default.
- W2016022093 hasRelatedWork W2006139140 @default.
- W2016022093 hasRelatedWork W2023330742 @default.
- W2016022093 hasRelatedWork W2054518906 @default.
- W2016022093 hasRelatedWork W207297640 @default.
- W2016022093 hasRelatedWork W2081358646 @default.
- W2016022093 hasRelatedWork W2381667282 @default.
- W2016022093 hasRelatedWork W3007981733 @default.
- W2016022093 hasRelatedWork W3029156704 @default.
- W2016022093 hasRelatedWork W3200647722 @default.
- W2016022093 hasRelatedWork W4238636496 @default.
- W2016022093 hasVolume "11" @default.
- W2016022093 isParatext "false" @default.
- W2016022093 isRetracted "false" @default.
- W2016022093 magId "2016022093" @default.
- W2016022093 workType "article" @default.