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- W2016022436 abstract "In this study, we showed by Northern blot analysis and bioassays that scarcely differentiated human hepatoma cell line HA22T/VGH constitutively produces interleukin-6 (IL6). This cytokine was produced neither by moderately differentiated Li7A nor by well-differentiated HepG2 human hepatoma cell lines. The finding that transcripts for IL6 were not present in 2.2.15 cells, a HepG2-derived clone transfected with the intracellular replicative form of hepatitis B virus (HBV) DNA, suggests that production of this cytokine is not affected by HBV-encoded gene products, but is more likely related to the dedifferentiated state of hepatoma cells." @default.
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- W2016022436 date "1993-01-01" @default.
- W2016022436 modified "2023-09-27" @default.
- W2016022436 title "Interleukin-6 production by human hepatoma lines is related to a low degree of cell differentiation" @default.
- W2016022436 doi "https://doi.org/10.1016/s0923-2516(06)80048-8" @default.
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