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- W2016024341 abstract "CancerVolume 57, Issue 10 p. 1912-1917 ArticleFree Access Methotrexate resistance and gene amplification. Mechanisms and implications Robert T. Schimke, Robert T. SchimkeSearch for more papers by this author Robert T. Schimke, Robert T. SchimkeSearch for more papers by this author First published: 15 May 1986 https://doi.org/10.1002/1097-0142(19860515)57:10<1912::AID-CNCR2820571004>3.0.CO;2-OCitations: 52AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat References 1 Haber DA, Beverley SM, Kiely M, Schimke RT. Properties of an altered dihydrofolate reductase encoded by amplified genes in cultured mouse fibroblasts. J Biol Chem 1981; 256: 9501. 2 Sirotnak FM, Moccio DM, Kelleher LE, Goutas LJ. Relative frequency and kinetic properties of transport-defective phenotypes among methotrexate-resistant L1210 cell lines derived in vivo Cancer Res 1981; 41: 4447– 4452. 3 Haber DA, Schimke RT. Unstable amplification of an altered dihydrofolate reductase gene associated with double minute chromosomes. Cell 1982; 26: 355– 362. 4 Brown PE, Tlsty TD, Schimke RT. Enhancement of methotrexate resistance and dihydrofolate reductase gene amplification by treatment of mouse 3T6 cells with hydroxyurea. Mol Cell Biol 1983; 3: 1097– 2002. 5 Beidler JL, Spengler BA. Metaphase chromosome anomaly: Association with drug resistance and cell-specific products. Science 1976; 191: 185. 6 Nunberg JH, Kaufman RF, Schimke RT, Urlaub G, Chasin LA. Amplified dihydrofolate reductase genes are localized to a homogeneously staining region of a single chromosome in a methotrexate-resistant Chinese hamster ovary cell line. Proc Natl Acad Sci USA 1978; 75: 5553– 5556. 7 Kaufman RT, Brown PE, Schimke RT. Amplified dihydrofolate reductase genes in unstably methotrexate-resistant cells are associated with double minute chromosomes. Proc Natl Acad Sci USA 1979; 76: 5669– 5673. 8 Schimke RT, Brown PC, Kaufman RJ, McGrogan M, Slate DL. Chromosomal and extrachromosomal localization of amplified dihydrofolate reductase genes in cultured mammalian cells. Quant Biol 1981; 55: 785– 797. 9 Kaufman RJ, Schimke RT. Amplification and loss of dihydrofolate reductase genes in a Chinese hamster ovary cell line. Mol Cell Biol 1981; 1: 1069– 1076. 10 Hamkalo BA, Farnham PJ, Johnston R, Schimke RT. Ultrastructural features of minute chromosomes in a methotrexate-resistant mouse 3T3 cell line. Proc Natl Acad Sci USA 1985; 82: 1126– 1130. 11 Schimke RT. Gene amplification in cultured animal cells. Cell 1984; 37: 705– 713. 12 Kaufman RJ, Brown PC, Schimke RT. Loss and stabilization of amplified dihydrofolate reductase genes in mouse sarcoma S-180 cell lines. Mol Cell Biol 1981; 1: 1084– 1090. 13 Beverley SM, Coderre JA, Santi DV, Schimke RT. Unstable DNA amplifications in methotrexate-resistant Leishmania consist of extrachromosomal circles which relocalize during stabilization. Cell 1984; 38: 431. 14 Curt GA, Carney DN, Cowan KH et al. Unstable methotrexate resistance in human small-cell carcinoma associated with double minute chromosomes. N Engl J Med 1983; 208: 199. 15 Horns RC, Dower WJ, Schimke RT. Gene amplification in a leukemic patient treated with methotrexate. J Clin Oncol 1984; 2: 2– 7. 16 Trent JM, Buick RN, Olson S, Horns RC, Schimke RT. Cytologic evidence for gene amplification in methotrexate-resistant cells obtained from a patient with ovarian adenocarcinoma. J Clin Oncol 1984; 2: 8– 15. 17 Carman MD, Schomagel JH, Rivest RS et al. Resistance to methotrexate due to gene amplification in a patient with acute leukemia. Clin. Oncol 1984; 2: 16. 18 Johnston RN, Beverley SM, Schimke RT. Rapid spontaneous dihydrofolate reductase gene amplification shown by fluorescence-activated cell sorting. Proc Natl Acad Sci USA 1983; 80: 3711– 3715. 19 Tlsty TD, Brown PE, Schimke RT. UV radiation facilitates methotrexate resistance and amplification of the dihydrofolate reductase gene in cultured 3T6 mouse cells. Mol Cell Biol 1984; 4: 1050– 1056. 20 Tlsty TD, Brown PC, Johnston R, Schimke RT. Enhanced frequency of generation of methotrexate resistance and gene amplification in cultured mouse and hamster cell lines. In: RT Schimke, ed. Gene Amplification. Cold Spring Harbor, New York: Cold Spring Harbor Laboratory, 1982; 231– 238. 21 Sherwood S, unpublished. 22 Stark BR, Wahl GM. Gene amplification. Ann Rev Biochem. 1985; 53: 447– 492. 23 Anderson RP, Roth JR. Tandem genetic duplications in phage and bacteria. Ann Rev Microbiol 1977; 31: 473– 505. 24 Schimke RT, Alt FW, Kellems RE, Kaufman R, Bertino JR. Amplification of dihydrofolate reductase genes in methotrexate-resistant cultured mouse cells. Quant Biol 1978; 52: 649– 657. 25 Wahl GM, Padgett RA, Stark GR. Gene amplification causes overproduction of the first three enzymes of UMP synthesis in N-(phosphoacetyl-1-aspartate) resistant hamster cells. J Biol Chem 1979; 254: 8679– 8689. 26 Beach LR, Palmiter RD. Amplification of the metallothionein-1 gene in cadmium-resistant mouse cells. Proc Natl Acad Sci USA 1981; 78: 2110– 2114. 27 Chin DJ, Luskey KL, Anderson RGW et al. Appearance of crystalloid endoplasmic reticulum in compactin-resistant Chinese hamster cells with a 500-fold increase in 3-hydroxy-3-methyglutaryl-coenzyme A reductase. Proc Natl Acad Sci USA 1982; 79: 1185– 1189. 28 Yeung C-Y, Ingolia DE, Bobonis C et al. Selective overproduction of adenosine deaminase in cultured mouse cells. J Biol Chem 1983; 258: 8338– 8345. 29 McConlogue L, Gupta M, Wu L, Coffino P. Molecular cloning and expression of the mouse ornithine decarboxylase gene. Proc Natl Acad Sci USA 1984; 81: 540– 544. 30 Kanalas JJ, Suttle DP. Amplification of the UMP synthetase gene and enzyme overproduction in pyrazofurin-resistant rat hepatoma cells. J Biol Chem 1984; 259: 1848– 1853. 31 Roninson EG, Abelson HT, Housman DE, Howell N, Varshavsky A. Amplification of specific DNA sequences correlates with multidrug resistance in Chinese hamster cells. Nature 1984; 309: 626– 628. 32 Chattopadhyay SK, Chang EH, Lander MR et al. Amplification and rearrangement of onc genes in mammalian species. Nature 1982; 296: 361– 363. 33 Collins SJ, Groudine MT. Rearrangement and amplification of c-alb sequences in a human chronic myelogenous leukemia cell line K-562. Genetics 1983; 80: 4813– 4817. 34 Schwab M, Alitalo K, Varmus HE, Bishop JM, George D. A cellular oncogene (c-Ki-ras) is amplified, overexpressed and located within karyotypic abnormalities in mouse adrenocortical tumor cells. Nature 1983; 303: 497– 501. 35 Kohl NE, Kanda N, Schreck RR, Bruns G, Latt SA, Gilbert F, Alt FW. Transposition and amplification of oncogene-related sequences in human neuroblastomas. Cell 1983; 35: 359– 367. 36 Mariani BD, Schimke RT. Gene amplification in a single cell cycle in Chinese hamster ovary cells. J Biol Chem 1984; 259: 1091– 1910. 37 Hill AB, Schimke RT. Increased gene amplification in L5178Y mouse by lymphoma cells with hydroxyurea-induced chromosomal aberrations. Cancer Res 1985; 45: 5050– 5057. 38 Lavi S. Carcinogen-mediated amplification of viral DNA sequences in SV-40 transformed Chinese hamster embryo cells. Proc Natl Acad Sci USA 1981; 78: 6144– 6148. 39 Prichard RH, Lark KB. Induction of replication by thymine starvation at the chromosome origin in Escherichia coli. J Mol Biol 1964; 9: 288– 307. 40 Billen D. Replication of the bacterial chromosome: location of new initiation sites after irradiation. J Bacteriol 1969; 97: 1169– 1175. 41 Rice GC, Spiro IJ, Ling CC. Detection of S-phase overreplication following chronic hypoxia using a monoclonal anti-BrdU. Intl J Radiat Oncol 1985; 11: 1817– 1822. 41a Evenson DP, Prescott DM. Disruption of DNA synthesis in Euplotes by heat shock. Exptl Cell Res 1970; 63: 245– 252. 42 Spradling AC, Mahowald AP. Amplification of genes for chorion proteins during oogenesis in Drosophila melanogaster. Proc Natl Acad Sci USA 1980; 77: 1096– 2002. 43 Osheim YN, Miller OJ Jr. Novel amplification and transcriptional activity of chorion genes in Drosophila melanogaster follicle cells. Cell 1983; 33: 543– 553. 44 Beidler JL, Malera PW, Spengler BA. Specifically altered metaphase chromosomes in antifolate-resistant Chinese hamster cells that overproduce dihydrofolate reductase. Cancer Genet Cytogenet 1981; 2: 47. 45 Fougere-Deschatrette C, Schimke RT, Weil D, Weiss MC. A study of chromosomal changes associated with amplified dihydrofolate reductase genes in rat hepatoma cells and their dedifferentiated variants. J Cell Biol 1984; 99: 497. 46 Rath H, Tlsty TD, Schimke RT. Rapid emergence of methotrexate resistance in cultured mouse cells. Cancer Res 1984; 44: 3303– 3306. 47 Nowell PC. Tumors as clonal proliferation. Virchow's Arch (Cell Pathol) 1978; 29: 145– 150. 48 Miller DA, Miller OJ. Chromosomes and cancer in the mouse: Studies of tumors, established cell lines, and cell hydrids. Adv Cancer Res 1983; 39: 153– 182. 49 Sutherland GR. The fragile X chromosome. Int Rev Cytol 1983; 81: 107– 186. 50 Yunis JJ, Soreng AL. Constitutive fragile sites and cancer. Science 1984; 226: 1194– 1204. 51 Aver G, Zetterberg A. The prognostic significance of nuclear DNA content in malignant tumors of breast, prostate and cartilage. In: L Koss, J Coleman, eds. Advances in Clinical Cytology, vol. II; Chapter 6. New York: Academic Press, 1984. 52 deVere White R, Deitch AD, Olsson CA. Limitations of DNA histogram analysis by flow cytometry as method of predicting chemosensitivity in a rat renal cancer model. Cancer Res 1983; 43: 604. Citing Literature Volume57, Issue1015 May 1986Pages 1912-1917 ReferencesRelatedInformation" @default.
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- W2016024341 cites W130152560 @default.
- W2016024341 cites W1487534034 @default.
- W2016024341 cites W1503403102 @default.
- W2016024341 cites W1532212172 @default.
- W2016024341 cites W1546760200 @default.
- W2016024341 cites W1758061342 @default.
- W2016024341 cites W1832894081 @default.
- W2016024341 cites W195608166 @default.
- W2016024341 cites W1972920532 @default.
- W2016024341 cites W1982729145 @default.
- W2016024341 cites W1983741002 @default.
- W2016024341 cites W1986572701 @default.
- W2016024341 cites W1987234748 @default.
- W2016024341 cites W1988667160 @default.
- W2016024341 cites W1992607960 @default.
- W2016024341 cites W1994263437 @default.
- W2016024341 cites W2002039465 @default.
- W2016024341 cites W2008582329 @default.
- W2016024341 cites W2012731646 @default.
- W2016024341 cites W2017692699 @default.
- W2016024341 cites W2038108954 @default.
- W2016024341 cites W2042378550 @default.
- W2016024341 cites W2045890708 @default.
- W2016024341 cites W2051586659 @default.
- W2016024341 cites W2058519931 @default.
- W2016024341 cites W2058942998 @default.
- W2016024341 cites W2059334666 @default.
- W2016024341 cites W2063306206 @default.
- W2016024341 cites W2064038447 @default.
- W2016024341 cites W2066689347 @default.
- W2016024341 cites W2071235641 @default.
- W2016024341 cites W2071905683 @default.
- W2016024341 cites W2082749146 @default.
- W2016024341 cites W2115312355 @default.
- W2016024341 cites W2117741144 @default.
- W2016024341 cites W2118744932 @default.
- W2016024341 cites W2149671541 @default.
- W2016024341 cites W2178402621 @default.
- W2016024341 cites W2241733037 @default.
- W2016024341 cites W2256754836 @default.
- W2016024341 cites W3022009864 @default.
- W2016024341 cites W4236480550 @default.
- W2016024341 cites W4255942601 @default.
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