FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016024882> ?p ?o ?g. }

• W2016024882 endingPage "S66" @default.
• W2016024882 startingPage "S59" @default.
• W2016024882 abstract "1. Patients undergoing orthotopic liver transplantation (OLT) for hepatitis B without effective prophylaxis have a high risk for recurrent infection and severe graft damage, leading to death or re-OLT. 2. Long-term prophylaxis with hepatitis B immune globulin (HBIg) significantly reduces the risk for hepatitis B virus (HBV) recurrence and increases survival. Patients with detectable HBV DNA at the time of OLT have a high risk for recurrence despite HBIg prophylaxis. 3. Lamivudine (LAM) therapy for patients with decompensated HBV cirrhosis before OLT results in inhibition of viral replication and clinical improvement. Its efficacy is limited by the frequent emergence of LAM-resistant YMDD mutations. The ideal length of therapy with LAM pre-OLT has not yet been defined. 4. Prophylaxis of HBV recurrence with LAM monotherapy is not recommended because of the reappearance of hepatitis B surface antigen after OLT in approximately 50% of patients. 5. LAM is the best available treatment for patients with established recurrent hepatitis B. Long-term therapy is associated with the emergence of drug-resistant mutants in up to 60% of patients. Severe hepatitis and liver failure have been described among liver transplant recipients with YMDD mutations. 6. Combination therapy with HBIg and LAM prevents HBV recurrence in 90% to 100% of patients who undergo OLT for hepatitis B. The optimal HBIg protocol in the LAM era is yet to be defined. 7. Preliminary studies suggest that adefovir dipivoxil inhibits HBV replication in patients infected with LAM-resistant HBV strains. 8. Fifteen years ago, hepatitis B was regarded as a relative or absolute contraindication for OLT. Today, hepatitis B is a universally accepted indication for OLT." @default.
• W2016024882 created "2016-06-24" @default.
• W2016024882 creator A5088252677 @default.
• W2016024882 date "2002-10-01" @default.
• W2016024882 modified "2023-10-14" @default.
• W2016024882 title "Hepatitis B: Progress in the last 15 years" @default.
• W2016024882 cites W1518720720 @default.
• W2016024882 cites W1521196107 @default.
• W2016024882 cites W1581230849 @default.
• W2016024882 cites W1631028738 @default.
• W2016024882 cites W1968020358 @default.
• W2016024882 cites W1975963947 @default.
• W2016024882 cites W1976192241 @default.
• W2016024882 cites W1979835783 @default.
• W2016024882 cites W1981273162 @default.
• W2016024882 cites W1985423921 @default.
• W2016024882 cites W1986260234 @default.
• W2016024882 cites W1989120759 @default.
• W2016024882 cites W1991228857 @default.
• W2016024882 cites W1993313190 @default.
• W2016024882 cites W1999298724 @default.
• W2016024882 cites W2002333870 @default.
• W2016024882 cites W2003709460 @default.
• W2016024882 cites W2008818075 @default.
• W2016024882 cites W2009410984 @default.
• W2016024882 cites W2012573156 @default.
• W2016024882 cites W2013880268 @default.
• W2016024882 cites W2015214996 @default.
• W2016024882 cites W2033597506 @default.
• W2016024882 cites W2034998973 @default.
• W2016024882 cites W2036762632 @default.
• W2016024882 cites W2038801680 @default.
• W2016024882 cites W2041473795 @default.
• W2016024882 cites W2042653073 @default.
• W2016024882 cites W2044965443 @default.
• W2016024882 cites W2048159269 @default.
• W2016024882 cites W2049604384 @default.
• W2016024882 cites W2060231880 @default.
• W2016024882 cites W2060781265 @default.
• W2016024882 cites W2062979128 @default.
• W2016024882 cites W2063352208 @default.
• W2016024882 cites W2063432232 @default.
• W2016024882 cites W2063847769 @default.
• W2016024882 cites W2066036630 @default.
• W2016024882 cites W2066265094 @default.
• W2016024882 cites W2068399780 @default.
• W2016024882 cites W2071904124 @default.
• W2016024882 cites W2074355139 @default.
• W2016024882 cites W2075559061 @default.
• W2016024882 cites W2076932222 @default.
• W2016024882 cites W2084055006 @default.
• W2016024882 cites W2085249688 @default.
• W2016024882 cites W2086867812 @default.
• W2016024882 cites W2090126805 @default.
• W2016024882 cites W2091910482 @default.
• W2016024882 cites W2102266647 @default.
• W2016024882 cites W2104475182 @default.
• W2016024882 cites W2109316484 @default.
• W2016024882 cites W2111995033 @default.
• W2016024882 cites W2115371558 @default.
• W2016024882 cites W2117646612 @default.
• W2016024882 cites W2121397927 @default.
• W2016024882 cites W2122150362 @default.
• W2016024882 cites W2125312312 @default.
• W2016024882 cites W2127559947 @default.
• W2016024882 cites W2129955924 @default.
• W2016024882 cites W2142372490 @default.
• W2016024882 cites W2158084983 @default.
• W2016024882 cites W2158129085 @default.
• W2016024882 cites W2161471777 @default.
• W2016024882 cites W2167572870 @default.
• W2016024882 cites W2170843437 @default.
• W2016024882 cites W2402699220 @default.
• W2016024882 cites W4233222916 @default.
• W2016024882 doi "https://doi.org/10.1053/jlts.2002.35782" @default.
• W2016024882 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/12362301" @default.
• W2016024882 hasPublicationYear "2002" @default.
• W2016024882 type Work @default.
• W2016024882 sameAs 2016024882 @default.
• W2016024882 citedByCount "22" @default.
• W2016024882 countsByYear W20160248822013 @default.
• W2016024882 countsByYear W20160248822018 @default.
• W2016024882 countsByYear W20160248822019 @default.
• W2016024882 crossrefType "journal-article" @default.
• W2016024882 hasAuthorship W2016024882A5088252677 @default.
• W2016024882 hasConcept C126322002 @default.
• W2016024882 hasConcept C159047783 @default.
• W2016024882 hasConcept C203014093 @default.
• W2016024882 hasConcept C2522874641 @default.
• W2016024882 hasConcept C2776029263 @default.
• W2016024882 hasConcept C2777214474 @default.
• W2016024882 hasConcept C2777382497 @default.
• W2016024882 hasConcept C2777869810 @default.
• W2016024882 hasConcept C2779517838 @default.
• W2016024882 hasConcept C2779609443 @default.
• W2016024882 hasConcept C2780056496 @default.
• W2016024882 hasConcept C2780593183 @default.
• W2016024882 hasConcept C2911091166 @default.

• next