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- W2016028229 abstract "The c-fms proto-oncogene is a member of a gene family that has been implicated in tumorigenesis. Glycoproteins encoded by c-fms were identified in cat spleen cells by means of an immune-complex kinase assay performed with monoclonal antibodies to v-fms-coded epitopes. The major form of the normal cellular glycoprotein has an apparent molecular weight of 170,000 and, like the product of the viral oncogene, serves as a substrate for an associated tyrosine-specific protein kinase activity in vitro. The results suggest that the transforming glycoprotein specified by v-fms is a truncated form of a c-fms-coded growth factor receptor." @default.
- W2016028229 created "2016-06-24" @default.
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- W2016028229 date "1985-04-19" @default.
- W2016028229 modified "2023-09-30" @default.
- W2016028229 title "The Product of the c- <i>fms</i> Proto-Oncogene: a Glycoprotein with Associated Tyrosine Kinase Activity" @default.
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- W2016028229 doi "https://doi.org/10.1126/science.2580348" @default.
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