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- W2016029382 abstract "The birth of small-diameter TrkA+ neurons that mediate pain and thermoreception begins approximately 24 hours after the cessation of neural crest cell migration from progenitors residing in the nascent dorsal root ganglion. Although multiple geographically distinct progenitor pools have been proposed, this study is the first to comprehensively characterize the derivation of small-diameter neurons. In the developing chick embryo we identify novel patterns in neural crest cell migration and colonization that sculpt the incipient ganglion into a postmitotic neuronal core encapsulated by a layer of proliferative progenitor cells. Furthermore, we show that this outer progenitor layer is composed of three spatially, temporally, and molecularly distinct progenitor zones, two of which give rise to distinct populations of TrkA+ neurons." @default.
- W2016029382 created "2016-06-24" @default.
- W2016029382 creator A5010129042 @default.
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- W2016029382 creator A5073599890 @default.
- W2016029382 creator A5078745231 @default.
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- W2016029382 date "2010-02-15" @default.
- W2016029382 modified "2023-10-06" @default.
- W2016029382 title "Patterned assembly and neurogenesis in the chick dorsal root ganglion" @default.
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- W2016029382 doi "https://doi.org/10.1002/cne.22248" @default.
- W2016029382 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2892853" @default.
- W2016029382 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20017208" @default.
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