Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016036211> ?p ?o ?g. }
- W2016036211 endingPage "260" @default.
- W2016036211 startingPage "254" @default.
- W2016036211 abstract "CEP-1347 is a potent inhibitor of mixed lineage kinase (MLK), which was investigated for ameliorating HIV-associated neurocognitive disorders. CEP-1347 and atazanavir pharmacokinetics were determined when CEP-1347 50 mg twice daily was administered to HIV-infected patients (n = 20) receiving combination antiretroviral therapy including atazanavir and ritonavir (ATV/RTV, 300/100 mg) once daily continuously. Co-administration of CEP-1347 and ATV/RTV resulted with significant changes in pharmacokinetics of ATV but not RTV. Specifically, an increase in ATV accumulation ratio of 15 % (p = 0.007) and a prolongation of T 1/2 from 12.7 to 15.9 h (p = 0.002) were observed. The results suggested that co-administration of CEP-1347 with ATV/RTV in HIV-infected patients might result in limited impact on ATV but not on RTV pharmacokinetics." @default.
- W2016036211 created "2016-06-24" @default.
- W2016036211 creator A5017422398 @default.
- W2016036211 creator A5033967453 @default.
- W2016036211 creator A5037196439 @default.
- W2016036211 creator A5048851127 @default.
- W2016036211 creator A5055908944 @default.
- W2016036211 creator A5057507865 @default.
- W2016036211 creator A5062818118 @default.
- W2016036211 creator A5073227816 @default.
- W2016036211 creator A5075585167 @default.
- W2016036211 creator A5076244533 @default.
- W2016036211 date "2013-06-01" @default.
- W2016036211 modified "2023-10-17" @default.
- W2016036211 title "Pharmacokinetic interactions of CEP-1347 and atazanavir in HIV-infected patients" @default.
- W2016036211 cites W1489699963 @default.
- W2016036211 cites W1539290896 @default.
- W2016036211 cites W1555218238 @default.
- W2016036211 cites W1598588347 @default.
- W2016036211 cites W1833727709 @default.
- W2016036211 cites W1903105612 @default.
- W2016036211 cites W1918125126 @default.
- W2016036211 cites W1979814082 @default.
- W2016036211 cites W1987871624 @default.
- W2016036211 cites W1989181427 @default.
- W2016036211 cites W1991804565 @default.
- W2016036211 cites W1995493673 @default.
- W2016036211 cites W2005807968 @default.
- W2016036211 cites W2007943920 @default.
- W2016036211 cites W2022185380 @default.
- W2016036211 cites W2023090871 @default.
- W2016036211 cites W2023509447 @default.
- W2016036211 cites W2023830878 @default.
- W2016036211 cites W2030104330 @default.
- W2016036211 cites W2032959558 @default.
- W2016036211 cites W2035807473 @default.
- W2016036211 cites W2043281805 @default.
- W2016036211 cites W2058342631 @default.
- W2016036211 cites W2060264243 @default.
- W2016036211 cites W2068814836 @default.
- W2016036211 cites W2089585442 @default.
- W2016036211 cites W2090329397 @default.
- W2016036211 cites W2092018624 @default.
- W2016036211 cites W2095083924 @default.
- W2016036211 cites W2150627157 @default.
- W2016036211 cites W2153142245 @default.
- W2016036211 cites W2161017525 @default.
- W2016036211 cites W2790805946 @default.
- W2016036211 cites W4233451333 @default.
- W2016036211 cites W4243597021 @default.
- W2016036211 doi "https://doi.org/10.1007/s13365-013-0172-z" @default.
- W2016036211 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3760277" @default.
- W2016036211 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23737347" @default.
- W2016036211 hasPublicationYear "2013" @default.
- W2016036211 type Work @default.
- W2016036211 sameAs 2016036211 @default.
- W2016036211 citedByCount "10" @default.
- W2016036211 countsByYear W20160362112013 @default.
- W2016036211 countsByYear W20160362112015 @default.
- W2016036211 countsByYear W20160362112017 @default.
- W2016036211 countsByYear W20160362112018 @default.
- W2016036211 countsByYear W20160362112019 @default.
- W2016036211 countsByYear W20160362112023 @default.
- W2016036211 crossrefType "journal-article" @default.
- W2016036211 hasAuthorship W2016036211A5017422398 @default.
- W2016036211 hasAuthorship W2016036211A5033967453 @default.
- W2016036211 hasAuthorship W2016036211A5037196439 @default.
- W2016036211 hasAuthorship W2016036211A5048851127 @default.
- W2016036211 hasAuthorship W2016036211A5055908944 @default.
- W2016036211 hasAuthorship W2016036211A5057507865 @default.
- W2016036211 hasAuthorship W2016036211A5062818118 @default.
- W2016036211 hasAuthorship W2016036211A5073227816 @default.
- W2016036211 hasAuthorship W2016036211A5075585167 @default.
- W2016036211 hasAuthorship W2016036211A5076244533 @default.
- W2016036211 hasBestOaLocation W20160362112 @default.
- W2016036211 hasConcept C112705442 @default.
- W2016036211 hasConcept C142462285 @default.
- W2016036211 hasConcept C159047783 @default.
- W2016036211 hasConcept C2778414717 @default.
- W2016036211 hasConcept C2779298103 @default.
- W2016036211 hasConcept C2993143319 @default.
- W2016036211 hasConcept C3013748606 @default.
- W2016036211 hasConcept C71924100 @default.
- W2016036211 hasConcept C98274493 @default.
- W2016036211 hasConceptScore W2016036211C112705442 @default.
- W2016036211 hasConceptScore W2016036211C142462285 @default.
- W2016036211 hasConceptScore W2016036211C159047783 @default.
- W2016036211 hasConceptScore W2016036211C2778414717 @default.
- W2016036211 hasConceptScore W2016036211C2779298103 @default.
- W2016036211 hasConceptScore W2016036211C2993143319 @default.
- W2016036211 hasConceptScore W2016036211C3013748606 @default.
- W2016036211 hasConceptScore W2016036211C71924100 @default.
- W2016036211 hasConceptScore W2016036211C98274493 @default.
- W2016036211 hasIssue "3" @default.
- W2016036211 hasLocation W20160362111 @default.
- W2016036211 hasLocation W20160362112 @default.
- W2016036211 hasLocation W20160362113 @default.
- W2016036211 hasLocation W20160362114 @default.