FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016040388> ?p ?o ?g. }

• W2016040388 endingPage "5" @default.
• W2016040388 startingPage "1" @default.
• W2016040388 abstract "Background . Serum levels of the mannose-binding lectin (MBL), which is an activator of the complement system, have been considered as a pathogenic factor in a broad range of diseases, and means of modulating MBL are therefore being evaluated. In this study we examine the effects of weight loss on MBL levels, and in continuation of this if MBL is synthesized in human adipose tissue. Methods . 36 nondiabetic obese subjects received a very low-calorie diet (VLCD) of 800 kcal/day for 8 weeks. Blood samples were collected at baseline and after VLCD. Furthermore, we measured MBL mRNA levels by the real-time RT-PCR on human adipose tissue compared to liver tissue. Results . The mean body weight was reduced from<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M1><mml:mrow><mml:mn>106.3</mml:mn><mml:mo>±</mml:mo><mml:mn>2.6</mml:mn></mml:mrow></mml:math> kg to<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M2><mml:mrow><mml:mn>92.8</mml:mn><mml:mo>±</mml:mo><mml:mn>2.4</mml:mn></mml:mrow></mml:math> kg,<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M3><mml:mrow><mml:mi>P</mml:mi><mml:mo><</mml:mo><mml:mn>0.0001</mml:mn></mml:mrow></mml:math>. Median MBL at baseline was 746 μ g/L (IQR 316–1190) versus 892 μ g/L (IQR 336–1511) after 8 weeks,<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M4><mml:mrow><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>0.23</mml:mn></mml:mrow></mml:math>. No correlations were found between weight loss and changes in MBL (<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M5><mml:mrow><mml:mi>r</mml:mi><mml:mo>=</mml:mo><mml:mn>-0.098</mml:mn></mml:mrow></mml:math>,<mml:math xmlns:mml=http://www.w3.org/1998/Math/MathML id=M6><mml:mrow><mml:mi>P</mml:mi><mml:mo>=</mml:mo><mml:mn>0.57</mml:mn></mml:mrow></mml:math>). MBL real-time RT-PCR showed no expression of mRNA in adipose tissue, but as expected a good expression in liver tissue was seen. Conclusions . MBL levels are not affected by weight loss and MBL is not synthesized in human adipose tissue." @default.
• W2016040388 created "2016-06-24" @default.
• W2016040388 creator A5006404917 @default.
• W2016040388 creator A5035111372 @default.
• W2016040388 creator A5038022117 @default.
• W2016040388 creator A5049957130 @default.
• W2016040388 creator A5050545160 @default.
• W2016040388 creator A5075336824 @default.
• W2016040388 creator A5088598369 @default.
• W2016040388 date "2012-01-01" @default.
• W2016040388 modified "2023-10-16" @default.
• W2016040388 title "The Effect of Weight Loss on Serum Mannose-Binding Lectin Levels" @default.
• W2016040388 cites W1967351112 @default.
• W2016040388 cites W1981033024 @default.
• W2016040388 cites W1987032810 @default.
• W2016040388 cites W2007240114 @default.
• W2016040388 cites W2011846108 @default.
• W2016040388 cites W2022447857 @default.
• W2016040388 cites W2035570040 @default.
• W2016040388 cites W2060638617 @default.
• W2016040388 cites W2068408721 @default.
• W2016040388 cites W2069040800 @default.
• W2016040388 cites W2070618971 @default.
• W2016040388 cites W2074666551 @default.
• W2016040388 cites W2074919825 @default.
• W2016040388 cites W2085325953 @default.
• W2016040388 cites W2120390577 @default.
• W2016040388 cites W2122865912 @default.
• W2016040388 cites W2132355967 @default.
• W2016040388 cites W2135574819 @default.
• W2016040388 cites W2137318130 @default.
• W2016040388 cites W2151051800 @default.
• W2016040388 cites W2169801019 @default.
• W2016040388 cites W2171120557 @default.
• W2016040388 cites W2585732487 @default.
• W2016040388 cites W4235710785 @default.
• W2016040388 doi "https://doi.org/10.1155/2012/354894" @default.
• W2016040388 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3511836" @default.
• W2016040388 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/23227084" @default.
• W2016040388 hasPublicationYear "2012" @default.
• W2016040388 type Work @default.
• W2016040388 sameAs 2016040388 @default.
• W2016040388 citedByCount "5" @default.
• W2016040388 countsByYear W20160403882014 @default.
• W2016040388 countsByYear W20160403882017 @default.
• W2016040388 countsByYear W20160403882019 @default.
• W2016040388 countsByYear W20160403882022 @default.
• W2016040388 crossrefType "journal-article" @default.
• W2016040388 hasAuthorship W2016040388A5006404917 @default.
• W2016040388 hasAuthorship W2016040388A5035111372 @default.
• W2016040388 hasAuthorship W2016040388A5038022117 @default.
• W2016040388 hasAuthorship W2016040388A5049957130 @default.
• W2016040388 hasAuthorship W2016040388A5050545160 @default.
• W2016040388 hasAuthorship W2016040388A5075336824 @default.
• W2016040388 hasAuthorship W2016040388A5088598369 @default.
• W2016040388 hasBestOaLocation W20160403881 @default.
• W2016040388 hasConcept C11413529 @default.
• W2016040388 hasConcept C185592680 @default.
• W2016040388 hasConcept C33923547 @default.
• W2016040388 hasConceptScore W2016040388C11413529 @default.
• W2016040388 hasConceptScore W2016040388C185592680 @default.
• W2016040388 hasConceptScore W2016040388C33923547 @default.
• W2016040388 hasLocation W20160403881 @default.
• W2016040388 hasLocation W20160403882 @default.
• W2016040388 hasLocation W20160403883 @default.
• W2016040388 hasLocation W20160403884 @default.
• W2016040388 hasLocation W20160403885 @default.
• W2016040388 hasOpenAccess W2016040388 @default.
• W2016040388 hasPrimaryLocation W20160403881 @default.
• W2016040388 hasRelatedWork W1531601525 @default.
• W2016040388 hasRelatedWork W2319480705 @default.
• W2016040388 hasRelatedWork W2384464875 @default.
• W2016040388 hasRelatedWork W2398689458 @default.
• W2016040388 hasRelatedWork W2606230654 @default.
• W2016040388 hasRelatedWork W2607424097 @default.
• W2016040388 hasRelatedWork W2748952813 @default.
• W2016040388 hasRelatedWork W2899084033 @default.
• W2016040388 hasRelatedWork W2948807893 @default.
• W2016040388 hasRelatedWork W2778153218 @default.
• W2016040388 hasVolume "2012" @default.
• W2016040388 isParatext "false" @default.
• W2016040388 isRetracted "false" @default.
• W2016040388 magId "2016040388" @default.
• W2016040388 workType "article" @default.