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• W2016040663 startingPage "59" @default.
• W2016040663 abstract "Myelodysplastic syndromes (MDS) constitute a heterogeneous group of clonal hematopoietic disorders. Metaphase cytogenetics has been the gold standard for genetic testing in MDS, but it detects clonal cytogenetic abnormalities in only 50% of cases. New karyotyping tests include FISH, array-based comparative genomic hybridization and single-nucleotide polymorphism arrays. These techniques have increased the detected genetic abnormalities in MDS, many of which confer prognostic significance to overall and leukemia-free survival. This has eventually increased our understanding of MDS genetics. With the help of new technologies, we anticipate that the existing prognostic scoring systems will incorporate mutational data into their parameters. This review discusses the progress in MDS diagnosis through the use of array-based technologies. The authors also discuss the recently investigated genetic mutations in MDS and revisit the MDS classification and prognostic scoring systems." @default.
• W2016040663 created "2016-06-24" @default.
• W2016040663 creator A5055740968 @default.
• W2016040663 creator A5072169805 @default.
• W2016040663 creator A5077292257 @default.
• W2016040663 creator A5085974329 @default.
• W2016040663 date "2013-02-01" @default.
• W2016040663 modified "2023-09-26" @default.
• W2016040663 title "The need for additional genetic markers for myelodysplastic syndrome stratification: what does the future hold for prognostication?" @default.
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