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- W2016041359 abstract "Purpose: To describe an acquired, smooth white lesion of the caruncle and to underscore the role of subsurface keratinizing squamous epithelium in its formation. Methods: Clinical photographic documentation, histopathologic evaluation, and immunohistochemical staining of an excised specimen from a 25-year-old woman. Results: A cyst was found that was lined by keratinizing squamous epithelium without a keratohyaline layer (trichilemmal keratinization), typical of lesions of the pilosebaceous unit. A portion of the cyst's lining was replaced by granulomatous inflammation resulting from an earlier spontaneous partial rupture. Ki-67 immunolabeling demonstrated relatively few nuclei in S-phase (DNA synthesis) in comparison with the overlying epithelium, thereby suggesting an obstructive, nonproliferative cause for the cyst. Conclusion: A white caruncular lesion is a very rare finding according to the literature. It is most likely caused by a cyst lined by squamous epithelium elaborating trichilemmal-type keratin. A sebaceous gland duct was established as the source for the current lesion." @default.
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- W2016041359 date "2010-04-01" @default.
- W2016041359 modified "2023-10-17" @default.
- W2016041359 title "The White Caruncle: Sign of a Keratinous Cyst Arising From a Sebaceous Gland Duct" @default.
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- W2016041359 doi "https://doi.org/10.1097/ico.0b013e3181b55b5c" @default.
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