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- W2016050008 abstract "Very large, repulsive forces are measured between various surfaces in water at separations of about a nanometer or less. These forces are important in cryobiology because extracellular freezing usually causes extreme osmotic dehydration of cells. This brings membranes and macromolecules into close approach, and imposes large, anisotropic stresses on them. It is therefore important to study these forces at freezing temperatures. We have studied the freezing and thawing behaviour of lamellar phases of egg yolk lecithin and D2O. Force-hydration and force-separation relations are obtained from the deuterium nuclear magnetic resonance signal as a function of temperature. From these measurements we estimate the magnitude of freezing-induced membrane stresses and discuss their effect on the response of cells and organelles to freezing and thawing." @default.
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- W2016050008 date "1994-02-01" @default.
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- W2016050008 title "Hydration forces and membrane stresses: Cryobiological implications and a new technique for measurement" @default.
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- W2016050008 doi "https://doi.org/10.1016/0301-4622(93)e0081-f" @default.
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