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- W2016052104 abstract "The diagnosis of parathyroid overfunction or underfunction can be suspected clinically but can be established only by laboratory means. Development of a sensitive test for parathyroid hormone by the Berson and Yalow radioimmunoassay technique has paved the way for direct measurement of parathyroid function. With present techniques, however, hormone levels are elevated in only half the cases of proved hyperparathyroidism.1Undoubtedly, direct measurement of parathyroid hormone will be of great diagnostic value when the method is perfected. At present, however, parathyroid function is still estimated indirectly. The established actions ofexcessparathyroid hormone in man upon which tests of parathyroid function are based are (1) elevation of serum and urine calcium levels, for the most part due to mobilization of calcium from bone reservoirs, and (2) inhibition of renal tubular reabsorption of phosphate, often but not always resulting in hypophosphatemia. Secondarily, prolonged hypercalcemia may damage the kidney and uncompensated" @default.
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- W2016052104 date "1968-12-16" @default.
- W2016052104 modified "2023-10-07" @default.
- W2016052104 title "Laboratory Tests for Hyperparathyroidism" @default.
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- W2016052104 doi "https://doi.org/10.1001/jama.1968.03150120063018" @default.
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