Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016053172> ?p ?o ?g. }
- W2016053172 endingPage "H1053" @default.
- W2016053172 startingPage "H1041" @default.
- W2016053172 abstract "Although the application of a 9-V battery to the epicardial surface is a simple method of ventricular fibrillation induction, the fundamental mechanisms underlying this process remain unstudied. We used a combined experimental and modelling approach to understand how the interaction of direct current (DC) from a battery may induce reentrant activity within rabbit ventricles and its dependence on battery application timing and duration. A rabbit ventricular computational model was used to simulate 9-V battery stimulation for different durations at varying onset times during sinus rhythm. Corresponding high-resolution optical mapping measurements were conducted on rabbit hearts with DC stimuli applied via a relay system. DC application to diastolic tissue induced anodal and cathodal make excitations in both simulations and experiments. Subsequently, similar static epicardial virtual electrode patterns were formed that interacted with sinus beats but did not induce reentry. Upon battery release during diastole, break excitations caused single ectopics, similar to application, before sinus rhythm resumed. Reentry induction was possible for short battery applications when break excitations were slowed and forced to take convoluted pathways upon interaction with refractory tissue from prior make excitations or sinus beats. Short-lived reentrant activity could be induced for battery release shortly after a sinus beat for longer battery applications. In conclusion, the application of a 9-V battery to the epicardial surface induces reentry through a complex interaction of break excitations after battery release with prior induced make excitations or sinus beats." @default.
- W2016053172 created "2016-06-24" @default.
- W2016053172 creator A5012616951 @default.
- W2016053172 creator A5044242984 @default.
- W2016053172 creator A5065213444 @default.
- W2016053172 creator A5070481193 @default.
- W2016053172 creator A5073459250 @default.
- W2016053172 creator A5084260798 @default.
- W2016053172 creator A5084645060 @default.
- W2016053172 date "2014-04-01" @default.
- W2016053172 modified "2023-09-27" @default.
- W2016053172 title "Mechanism of reentry induction by a 9-V battery in rabbit ventricles" @default.
- W2016053172 cites W1574153307 @default.
- W2016053172 cites W1577968850 @default.
- W2016053172 cites W1603606472 @default.
- W2016053172 cites W1967951522 @default.
- W2016053172 cites W1969179215 @default.
- W2016053172 cites W1983574832 @default.
- W2016053172 cites W1988136878 @default.
- W2016053172 cites W1994043885 @default.
- W2016053172 cites W2000649098 @default.
- W2016053172 cites W2016302489 @default.
- W2016053172 cites W2024923246 @default.
- W2016053172 cites W2037613535 @default.
- W2016053172 cites W2042316811 @default.
- W2016053172 cites W2060046367 @default.
- W2016053172 cites W2070024016 @default.
- W2016053172 cites W2092203070 @default.
- W2016053172 cites W2098044063 @default.
- W2016053172 cites W2107188220 @default.
- W2016053172 cites W2117631027 @default.
- W2016053172 cites W2119899260 @default.
- W2016053172 cites W2120833574 @default.
- W2016053172 cites W2129851254 @default.
- W2016053172 cites W2129960920 @default.
- W2016053172 cites W2135085097 @default.
- W2016053172 cites W2146791281 @default.
- W2016053172 cites W2149529682 @default.
- W2016053172 cites W2548541194 @default.
- W2016053172 cites W31892762 @default.
- W2016053172 cites W2090064732 @default.
- W2016053172 doi "https://doi.org/10.1152/ajpheart.00591.2013" @default.
- W2016053172 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/3962639" @default.
- W2016053172 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/24464758" @default.
- W2016053172 hasPublicationYear "2014" @default.
- W2016053172 type Work @default.
- W2016053172 sameAs 2016053172 @default.
- W2016053172 citedByCount "7" @default.
- W2016053172 countsByYear W20160531722014 @default.
- W2016053172 countsByYear W20160531722016 @default.
- W2016053172 countsByYear W20160531722018 @default.
- W2016053172 countsByYear W20160531722019 @default.
- W2016053172 countsByYear W20160531722021 @default.
- W2016053172 countsByYear W20160531722022 @default.
- W2016053172 crossrefType "journal-article" @default.
- W2016053172 hasAuthorship W2016053172A5012616951 @default.
- W2016053172 hasAuthorship W2016053172A5044242984 @default.
- W2016053172 hasAuthorship W2016053172A5065213444 @default.
- W2016053172 hasAuthorship W2016053172A5070481193 @default.
- W2016053172 hasAuthorship W2016053172A5073459250 @default.
- W2016053172 hasAuthorship W2016053172A5084260798 @default.
- W2016053172 hasAuthorship W2016053172A5084645060 @default.
- W2016053172 hasBestOaLocation W20160531722 @default.
- W2016053172 hasConcept C121332964 @default.
- W2016053172 hasConcept C136229726 @default.
- W2016053172 hasConcept C163258240 @default.
- W2016053172 hasConcept C164705383 @default.
- W2016053172 hasConcept C189809214 @default.
- W2016053172 hasConcept C192562407 @default.
- W2016053172 hasConcept C24890656 @default.
- W2016053172 hasConcept C2775914520 @default.
- W2016053172 hasConcept C2777720157 @default.
- W2016053172 hasConcept C2779161974 @default.
- W2016053172 hasConcept C2781005686 @default.
- W2016053172 hasConcept C555008776 @default.
- W2016053172 hasConcept C62520636 @default.
- W2016053172 hasConcept C70616116 @default.
- W2016053172 hasConcept C71924100 @default.
- W2016053172 hasConceptScore W2016053172C121332964 @default.
- W2016053172 hasConceptScore W2016053172C136229726 @default.
- W2016053172 hasConceptScore W2016053172C163258240 @default.
- W2016053172 hasConceptScore W2016053172C164705383 @default.
- W2016053172 hasConceptScore W2016053172C189809214 @default.
- W2016053172 hasConceptScore W2016053172C192562407 @default.
- W2016053172 hasConceptScore W2016053172C24890656 @default.
- W2016053172 hasConceptScore W2016053172C2775914520 @default.
- W2016053172 hasConceptScore W2016053172C2777720157 @default.
- W2016053172 hasConceptScore W2016053172C2779161974 @default.
- W2016053172 hasConceptScore W2016053172C2781005686 @default.
- W2016053172 hasConceptScore W2016053172C555008776 @default.
- W2016053172 hasConceptScore W2016053172C62520636 @default.
- W2016053172 hasConceptScore W2016053172C70616116 @default.
- W2016053172 hasConceptScore W2016053172C71924100 @default.
- W2016053172 hasIssue "7" @default.
- W2016053172 hasLocation W20160531721 @default.
- W2016053172 hasLocation W20160531722 @default.
- W2016053172 hasLocation W20160531723 @default.
- W2016053172 hasLocation W20160531724 @default.