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- W201606975 abstract "Stem cells constitute the source of differentiated cells for the generation of tissues during development and for regeneration of tissues that are diseased or injured postnatally. Stem cell-based therapy often requires a scaffold to carry cells and/or growth factor to the injured site. Porous silicon (PSi) is a promising biomaterial for tissue engineering, as it is both non-toxic and bioresorbable. Surface modification can offer control over the degradation rate of PSi and can also impart properties to promote cell adhesion. Thus, coupling the good proliferation and differentiation capacities of either adult mesenchymal stem cells (MSC) or embryonic stem cells (ESC) with the textural and chemical properties of the PSi substrates provides an interesting approach for therapeutic use. Moreover, the PSi nanostructure and the release of silicic acid have positive effect on precursor cell osteodifferentiation and mineralized matrix formation." @default.
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- W201606975 date "2014-01-01" @default.
- W201606975 modified "2023-10-18" @default.
- W201606975 title "Porous silicon scaffolds for stem cells growth and osteodifferentiation" @default.
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