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- W2016074502 abstract "Autoimmunity is a complex disease process that results from a breakdown in the ability of the immune system to discriminate self from non-self. One approach to unraveling how autoimmunity occurs is to study monogenic diseases, for which a single gene defect is responsible. Recent work on the monogenic autoimmune disease 'autoimmune polyglandular syndrome type 1' (APS1) and on the causal gene of this disorder--autoimmune regulator (AIRE)--is providing new lessons on how immune tolerance is maintained." @default.
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- W2016074502 date "2007-06-01" @default.
- W2016074502 modified "2023-10-17" @default.
- W2016074502 title "Lessons on immune tolerance from the monogenic disease APS1" @default.
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- W2016074502 doi "https://doi.org/10.1016/j.gde.2007.04.001" @default.
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