Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016081971> ?p ?o ?g. }
- W2016081971 endingPage "588" @default.
- W2016081971 startingPage "572" @default.
- W2016081971 abstract "How the crowded environment inside cells affects folding, stability and structures of proteins is a vital question, since most proteins are made and function inside cells. Here we describe how crowded conditions can be created in vitro and in silico and how we have used this to probe effects on protein properties. We have found that folded forms of proteins become more compact in the presence of macromolecular crowding agents; if the protein is aspherical, the shape also changes (extent dictated by native-state stability and chemical conditions). It was also discovered that the shape of the macromolecular crowding agent modulates the folding mechanism of a protein; in addition, the extent of asphericity of the protein itself is an important factor in defining its folding speed." @default.
- W2016081971 created "2016-06-24" @default.
- W2016081971 creator A5042375063 @default.
- W2016081971 creator A5063954863 @default.
- W2016081971 creator A5070626230 @default.
- W2016081971 date "2009-02-13" @default.
- W2016081971 modified "2023-09-23" @default.
- W2016081971 title "Folding, Stability and Shape of Proteins in Crowded Environments: Experimental and Computational Approaches" @default.
- W2016081971 cites W1494980656 @default.
- W2016081971 cites W1729636218 @default.
- W2016081971 cites W1818942627 @default.
- W2016081971 cites W1968149059 @default.
- W2016081971 cites W1970948529 @default.
- W2016081971 cites W1977568127 @default.
- W2016081971 cites W1984865271 @default.
- W2016081971 cites W1991921179 @default.
- W2016081971 cites W1995838356 @default.
- W2016081971 cites W2003744642 @default.
- W2016081971 cites W2007867586 @default.
- W2016081971 cites W2008900559 @default.
- W2016081971 cites W2018204002 @default.
- W2016081971 cites W2023002165 @default.
- W2016081971 cites W2025017841 @default.
- W2016081971 cites W2027163663 @default.
- W2016081971 cites W2027191063 @default.
- W2016081971 cites W2027913596 @default.
- W2016081971 cites W2029750840 @default.
- W2016081971 cites W2030603945 @default.
- W2016081971 cites W2036507354 @default.
- W2016081971 cites W2037658617 @default.
- W2016081971 cites W2040809566 @default.
- W2016081971 cites W2041804296 @default.
- W2016081971 cites W2060222676 @default.
- W2016081971 cites W2060512844 @default.
- W2016081971 cites W2064446384 @default.
- W2016081971 cites W2065864578 @default.
- W2016081971 cites W2068246020 @default.
- W2016081971 cites W2072261891 @default.
- W2016081971 cites W2078862798 @default.
- W2016081971 cites W2083017600 @default.
- W2016081971 cites W2084572582 @default.
- W2016081971 cites W2085519055 @default.
- W2016081971 cites W2089597488 @default.
- W2016081971 cites W2096289954 @default.
- W2016081971 cites W2096795069 @default.
- W2016081971 cites W2098004479 @default.
- W2016081971 cites W2098487677 @default.
- W2016081971 cites W2102059060 @default.
- W2016081971 cites W2109610280 @default.
- W2016081971 cites W2112154906 @default.
- W2016081971 cites W2118763814 @default.
- W2016081971 cites W2123419409 @default.
- W2016081971 cites W2124170739 @default.
- W2016081971 cites W2129213941 @default.
- W2016081971 cites W2132881646 @default.
- W2016081971 cites W2143662775 @default.
- W2016081971 cites W2144729032 @default.
- W2016081971 cites W2150705673 @default.
- W2016081971 cites W2150766477 @default.
- W2016081971 cites W2154553490 @default.
- W2016081971 cites W2156291467 @default.
- W2016081971 cites W2156458781 @default.
- W2016081971 cites W2158476854 @default.
- W2016081971 cites W2160721947 @default.
- W2016081971 cites W2161596727 @default.
- W2016081971 cites W2165360511 @default.
- W2016081971 cites W2165847215 @default.
- W2016081971 cites W2169113904 @default.
- W2016081971 cites W344947223 @default.
- W2016081971 doi "https://doi.org/10.3390/ijms10020572" @default.
- W2016081971 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/2660654" @default.
- W2016081971 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/19333422" @default.
- W2016081971 hasPublicationYear "2009" @default.
- W2016081971 type Work @default.
- W2016081971 sameAs 2016081971 @default.
- W2016081971 citedByCount "62" @default.
- W2016081971 countsByYear W20160819712012 @default.
- W2016081971 countsByYear W20160819712013 @default.
- W2016081971 countsByYear W20160819712014 @default.
- W2016081971 countsByYear W20160819712015 @default.
- W2016081971 countsByYear W20160819712016 @default.
- W2016081971 countsByYear W20160819712017 @default.
- W2016081971 countsByYear W20160819712018 @default.
- W2016081971 countsByYear W20160819712019 @default.
- W2016081971 countsByYear W20160819712020 @default.
- W2016081971 countsByYear W20160819712021 @default.
- W2016081971 countsByYear W20160819712022 @default.
- W2016081971 countsByYear W20160819712023 @default.
- W2016081971 crossrefType "journal-article" @default.
- W2016081971 hasAuthorship W2016081971A5042375063 @default.
- W2016081971 hasAuthorship W2016081971A5063954863 @default.
- W2016081971 hasAuthorship W2016081971A5070626230 @default.
- W2016081971 hasBestOaLocation W20160819711 @default.
- W2016081971 hasConcept C104317684 @default.
- W2016081971 hasConcept C112972136 @default.
- W2016081971 hasConcept C119599485 @default.
- W2016081971 hasConcept C119857082 @default.
- W2016081971 hasConcept C12554922 @default.