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- W2016086415 abstract "[13N]- and [11C]carbamyl phosphate, l-[ω-13N]citrulline, l-[ureido-11C]citrulline, [carbamyl-13N]- and [carbamyl-11C]carbamyl-l-aspartate were synthesized using carbamyl phosphate synthetase coimmobilized with either aspartate transcarbamylase or ornithine transcarbamylase. Carbamyl l-[13N]aspartate was enzymatically prepared from carbamyl phosphate and l-[13N]aspartate. The tissue distribution of radioactivity in mice after injection of radiolabeled ammonia, carbamyl phosphate or citrulline was studied. The tissue distribution of isotope derived from [13N)carbamyl phosphate and [13N]ammonia were similar, with the exception of liver, brain and pancreas, in which 13NH3 uptake was higher after retroorbital injection. The distribution of label derived from l-[ω-13N]- and l-[ureido-13C]citrulline was similar. Substantial tumor (Sarcoma-180) uptake of label from l-citrulline was observed." @default.
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- W2016086415 title "Enzymatic syntheses of phosphate, l-citrulline, and N-carbamyl l-aspartate labeled with either 13N or 11C" @default.
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- W2016086415 doi "https://doi.org/10.1016/0047-0740(85)90031-2" @default.
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