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• W2016088378 abstract "We determined the disinfection efficiency of chlorine and chlorine dioxide (ClO2) using murine norovirus (MNV) and coliphage MS2 as surrogates for human norovirus. Experiments were performed in oxidant demand-free buffer (pH 7.2) at 5 °C and 20 °C. The extent of virus inactivation by a disinfectant was quantified using three different analytical methods: plaque, short template real-time TaqMan reverse transcriptase-polymerase chain reaction (RT-PCR), and long template RT-PCR assays. Rapid inactivation of MNV by both chlorine and chlorine dioxide was observed by the plaque assay. According to the efficiency factor Hom model, Ct values of 0.314 mg/L min and 0.247 mg/L min were required for a 4-log reduction of MNV at 5 °C by chlorine and chlorine dioxide, respectively. Lower Ct values were required at 20 °C. Both long template and short template RT-PCR assays significantly underestimated the virus inactivation compared to the plaque assay. Our study demonstrates that adequate treatment of water with either chlorine or ClO2 is likely to effectively control the waterborne transmission of human norovirus." @default.
• W2016088378 created "2016-06-24" @default.
• W2016088378 creator A5000774459 @default.
• W2016088378 creator A5059061731 @default.
• W2016088378 creator A5063895922 @default.
• W2016088378 date "2010-05-01" @default.
• W2016088378 modified "2023-10-11" @default.
• W2016088378 title "Disinfection kinetics of murine norovirus using chlorine and chlorine dioxide" @default.
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• W2016088378 doi "https://doi.org/10.1016/j.watres.2010.03.003" @default.
• W2016088378 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/20356616" @default.
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