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- W2016089727 abstract "During the centuries, surgeons have contributed to the advance of the medicine improving the surgical outcomes in daily clinical practice and participating to the progress of the basic research science. In 1909, Dr. Teododor Koker was the first surgeon to win the Nobel Prize, and in 1990, Dr. Joseph Murray was the seventh and the last surgeon to reach the award [1]. Therefore, together with other academic figures traditionally more oriented towards basic science, the surgeon always had an irreplaceable role in the development of medical science from both points of view, practical and intellectual through a process of gradual awareness and participation in the development of the research projects [2]. In recent years, the explosion of molecular biology has shown that this discipline, often confined to basic research, occupies an important place in surgical research. The impact on clinical practice varies from the analysis of molecular biomarkers and genetic risk of cancer to the application of transgenic technologies in xenografts [3]. Playing in this scenario, the question about the role of the surgeon in translational research and basic science becomes every day more urgent to plane the future of the Academic Departments of Surgery, whose central mission is to produce new knowledge and validate the laboratory results in the clinical practice. Therefore, looking at this radical change of perspective, the academic surgical community is called to answer several questions. Is it sufficient for us to be a good surgeon focused only on the quality of care or worth equipping and accepting the challenge, playing a game in an integrated research system? Could the strong practical experience of the surgical disciplines improve the theoretical approaches of basic sciences? Could the privileged relationship with the patient help to humanize the research interpreting the deepest need of the human being? Could the surgeon contribute to drive the results of basic science towards clinical applications in the era of genomics and proteomics? All these questions converge towards the conclusions that in the future academic surgeons will have a key role in the development of translational research program, and the surgical community needs to re-address our own vision of the research [4]." @default.
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- W2016089727 date "2012-11-22" @default.
- W2016089727 modified "2023-09-25" @default.
- W2016089727 title "Basic science, translational research and surgery: an unresolved controversy" @default.
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- W2016089727 doi "https://doi.org/10.1007/s13304-012-0185-9" @default.
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