FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016090826> ?p ?o ?g. }

• W2016090826 endingPage "12" @default.
• W2016090826 startingPage "1" @default.
• W2016090826 abstract "We reviewed data from 24 transplant centers in Asia, Australia, Europe, and North America to determine the outcomes of stem cell collection including methods used, cell yields, effects on disease activity, and complications in patients with autoimmune diseases. Twenty-one unprimed bone marrow harvests and 174 peripheral blood stem cell mobilizations were performed on 187 patients. Disease indications were multiple sclerosis (76 patients), rheumatoid arthritis (37 patients), scleroderma (26 patients), systemic lupus erythematosus (19 patients), juvenile chronic arthritis (13 patients), idiopathic autoimmune thrombocytopenia (8 patients), Behcet's disease (3 patients), undifferentiated vasculitis (3 patients), polychondritis (1 patient) and polymyositis (1 patient). Bone marrow harvests were used in the Peoples Republic of China and preferred worldwide for children. PBSC mobilization was the preferred technique for adult stem cell collection in America, Australia, and Europe. Methods of PBSC mobilization included G-CSF (5, 10, or 16 microg/kg/day) or cyclophosphamide (2 or 4 g/m2) with either G-CSF (5 or 10 microg/kg/day) or GM-CSF (5 microg/kg/day). Bone marrow harvests were without complications and did not affect disease activity. A combination of cyclophosphamide and G-CSF was more likely to ameliorate disease activity than G-CSF alone (P < 0.001). g-csf alone was more likely to cause disease exacerbation than the combination of cyclophosphamide and g-csf (P = 0.003). Three patients died as a result of cyclophosphamide-based stem cell collection (2.6% of patients mobilized with cyclophosphamide). When corrected for patient weight and apheresis volume, progenitor cell yields tended to vary by underlying disease, prior medication history and mobilization regimen. Trends in the approaches to, and results of, progenitor cell mobilization are suggested by this survey. While cytokine-based mobilization appears less toxic, it is more likely to result in disease reactivation. Optimization with regard to cell yields and safety are likely to be disease-specific and prospective disease-specific studies of mobilization procedures appear warranted." @default.
• W2016090826 created "2016-06-24" @default.
• W2016090826 creator A5007440569 @default.
• W2016090826 creator A5017909971 @default.
• W2016090826 creator A5025494836 @default.
• W2016090826 creator A5032815689 @default.
• W2016090826 creator A5034008882 @default.
• W2016090826 creator A5044386973 @default.
• W2016090826 creator A5055180780 @default.
• W2016090826 creator A5065409070 @default.
• W2016090826 creator A5069769583 @default.
• W2016090826 creator A5070464863 @default.
• W2016090826 creator A5074509169 @default.
• W2016090826 creator A5081343057 @default.
• W2016090826 creator A5084457753 @default.
• W2016090826 date "2001-07-01" @default.
• W2016090826 modified "2023-10-18" @default.
• W2016090826 title "Collection of hematopoietic stem cells from patients with autoimmune diseases" @default.
• W2016090826 cites W1521704076 @default.
• W2016090826 cites W1576927565 @default.
• W2016090826 cites W1966700293 @default.
• W2016090826 cites W1985551317 @default.
• W2016090826 cites W1987797799 @default.
• W2016090826 cites W1989180597 @default.
• W2016090826 cites W1993450847 @default.
• W2016090826 cites W2007730297 @default.
• W2016090826 cites W2010128921 @default.
• W2016090826 cites W2011044675 @default.
• W2016090826 cites W2011593628 @default.
• W2016090826 cites W2012194350 @default.
• W2016090826 cites W2015214829 @default.
• W2016090826 cites W2019336721 @default.
• W2016090826 cites W2019429109 @default.
• W2016090826 cites W2035966634 @default.
• W2016090826 cites W2036913446 @default.
• W2016090826 cites W2064999867 @default.
• W2016090826 cites W2076790865 @default.
• W2016090826 cites W2084345254 @default.
• W2016090826 cites W2087175225 @default.
• W2016090826 cites W2087393710 @default.
• W2016090826 cites W2098092330 @default.
• W2016090826 cites W2098487604 @default.
• W2016090826 cites W2102248390 @default.
• W2016090826 cites W2112165124 @default.
• W2016090826 cites W2115685550 @default.
• W2016090826 cites W2120128746 @default.
• W2016090826 cites W2124010998 @default.
• W2016090826 cites W2129260452 @default.
• W2016090826 cites W2129581710 @default.
• W2016090826 cites W2134960542 @default.
• W2016090826 cites W2137798261 @default.
• W2016090826 cites W2144229841 @default.
• W2016090826 cites W2148022337 @default.
• W2016090826 cites W2152223612 @default.
• W2016090826 cites W2157632927 @default.
• W2016090826 cites W2161341032 @default.
• W2016090826 cites W2162272900 @default.
• W2016090826 cites W2164725506 @default.
• W2016090826 cites W2172135937 @default.
• W2016090826 cites W2314500058 @default.
• W2016090826 cites W2324449270 @default.
• W2016090826 cites W2336801634 @default.
• W2016090826 cites W4251093572 @default.
• W2016090826 doi "https://doi.org/10.1038/sj.bmt.1703081" @default.
• W2016090826 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/11498738" @default.
• W2016090826 hasPublicationYear "2001" @default.
• W2016090826 type Work @default.
• W2016090826 sameAs 2016090826 @default.
• W2016090826 citedByCount "120" @default.
• W2016090826 countsByYear W20160908262012 @default.
• W2016090826 countsByYear W20160908262013 @default.
• W2016090826 countsByYear W20160908262015 @default.
• W2016090826 countsByYear W20160908262016 @default.
• W2016090826 countsByYear W20160908262017 @default.
• W2016090826 countsByYear W20160908262018 @default.
• W2016090826 countsByYear W20160908262019 @default.
• W2016090826 countsByYear W20160908262020 @default.
• W2016090826 countsByYear W20160908262021 @default.
• W2016090826 countsByYear W20160908262022 @default.
• W2016090826 countsByYear W20160908262023 @default.
• W2016090826 crossrefType "journal-article" @default.
• W2016090826 hasAuthorship W2016090826A5007440569 @default.
• W2016090826 hasAuthorship W2016090826A5017909971 @default.
• W2016090826 hasAuthorship W2016090826A5025494836 @default.
• W2016090826 hasAuthorship W2016090826A5032815689 @default.
• W2016090826 hasAuthorship W2016090826A5034008882 @default.
• W2016090826 hasAuthorship W2016090826A5044386973 @default.
• W2016090826 hasAuthorship W2016090826A5055180780 @default.
• W2016090826 hasAuthorship W2016090826A5065409070 @default.
• W2016090826 hasAuthorship W2016090826A5069769583 @default.
• W2016090826 hasAuthorship W2016090826A5070464863 @default.
• W2016090826 hasAuthorship W2016090826A5074509169 @default.
• W2016090826 hasAuthorship W2016090826A5081343057 @default.
• W2016090826 hasAuthorship W2016090826A5084457753 @default.
• W2016090826 hasBestOaLocation W20160908261 @default.
• W2016090826 hasConcept C126322002 @default.
• W2016090826 hasConcept C203014093 @default.
• W2016090826 hasConcept C2776694085 @default.

• next