Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016092362> ?p ?o ?g. }
Showing items 1 to 95 of
95
with 100 items per page.
- W2016092362 endingPage "2394" @default.
- W2016092362 startingPage "2390" @default.
- W2016092362 abstract "Transit of newly synthesized triacyl[3H]-glycerol through organelles of the secretory system leading to assembly into nascent very low density lipoproteins (VLDLs) or to cytoplasmic storage was investigated in chick hepatocytes. Cells in monolayer culture were pulse-labeled with [2-3H]glycerol, and after different periods of chase with unlabeled glycerol, the movement of triacyl[3H]glycerol through the endoplasmic reticulum (ER) and Golgi and the incorporation into nascent VLDL and cytoplasmic triacylglycerol-rich vesicles (TGRVs) were determined. Initially, newly synthesized triacyl[3H]glycerol is tightly associated with the ER. Movement from the ER of triacyl[3H]glycerol destined for cytoplasmic storage (as TGRVs) is extremely rapid and virtually complete within 8 min of chase. After 8 min of chase, triacyl[3H]glycerol lost from organelles of the secretory system was accounted for entirely as triacyl[3H]glycerol secreted as VLDL. Comparison of the rates of movement of triacyl[3H]glycerol, apolipoprotein B, apolipoprotein II, and apolipoprotein A-I through the ER and Golgi and of their secretion in nascent VLDL suggests that assembly of triacyglycerol with apolipoproteins occurs in the Golgi. Experiments with permeabilized hepatocytes supplemented with cytosol show that newly synthesized triacyl[3H]glycerol and [3H]phospholipid moves from the ER through the full-density range of Golgi elements and is dependent upon supplementary ATP." @default.
- W2016092362 created "2016-06-24" @default.
- W2016092362 creator A5032755793 @default.
- W2016092362 creator A5063465403 @default.
- W2016092362 date "1990-04-01" @default.
- W2016092362 modified "2023-09-29" @default.
- W2016092362 title "Possible role of the Golgi apparatus in the assembly of very low density lipoprotein." @default.
- W2016092362 cites W1486424025 @default.
- W2016092362 cites W1492377313 @default.
- W2016092362 cites W1498346306 @default.
- W2016092362 cites W1514192489 @default.
- W2016092362 cites W1526815729 @default.
- W2016092362 cites W1538584303 @default.
- W2016092362 cites W1545309548 @default.
- W2016092362 cites W1571225670 @default.
- W2016092362 cites W2022604481 @default.
- W2016092362 cites W2024739169 @default.
- W2016092362 cites W2055920490 @default.
- W2016092362 cites W2073479996 @default.
- W2016092362 cites W2134016419 @default.
- W2016092362 cites W2152311269 @default.
- W2016092362 cites W2164226796 @default.
- W2016092362 cites W2177551494 @default.
- W2016092362 cites W2402354430 @default.
- W2016092362 doi "https://doi.org/10.1073/pnas.87.7.2390" @default.
- W2016092362 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/53694" @default.
- W2016092362 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/2181435" @default.
- W2016092362 hasPublicationYear "1990" @default.
- W2016092362 type Work @default.
- W2016092362 sameAs 2016092362 @default.
- W2016092362 citedByCount "54" @default.
- W2016092362 countsByYear W20160923622012 @default.
- W2016092362 countsByYear W20160923622013 @default.
- W2016092362 countsByYear W20160923622017 @default.
- W2016092362 countsByYear W20160923622018 @default.
- W2016092362 crossrefType "journal-article" @default.
- W2016092362 hasAuthorship W2016092362A5032755793 @default.
- W2016092362 hasAuthorship W2016092362A5063465403 @default.
- W2016092362 hasBestOaLocation W20160923622 @default.
- W2016092362 hasConcept C119062480 @default.
- W2016092362 hasConcept C130316041 @default.
- W2016092362 hasConcept C158617107 @default.
- W2016092362 hasConcept C168240541 @default.
- W2016092362 hasConcept C185592680 @default.
- W2016092362 hasConcept C190062978 @default.
- W2016092362 hasConcept C2778163477 @default.
- W2016092362 hasConcept C2780072125 @default.
- W2016092362 hasConcept C2780881558 @default.
- W2016092362 hasConcept C41625074 @default.
- W2016092362 hasConcept C49039625 @default.
- W2016092362 hasConcept C55493867 @default.
- W2016092362 hasConcept C62746215 @default.
- W2016092362 hasConcept C8243546 @default.
- W2016092362 hasConcept C86803240 @default.
- W2016092362 hasConcept C95444343 @default.
- W2016092362 hasConceptScore W2016092362C119062480 @default.
- W2016092362 hasConceptScore W2016092362C130316041 @default.
- W2016092362 hasConceptScore W2016092362C158617107 @default.
- W2016092362 hasConceptScore W2016092362C168240541 @default.
- W2016092362 hasConceptScore W2016092362C185592680 @default.
- W2016092362 hasConceptScore W2016092362C190062978 @default.
- W2016092362 hasConceptScore W2016092362C2778163477 @default.
- W2016092362 hasConceptScore W2016092362C2780072125 @default.
- W2016092362 hasConceptScore W2016092362C2780881558 @default.
- W2016092362 hasConceptScore W2016092362C41625074 @default.
- W2016092362 hasConceptScore W2016092362C49039625 @default.
- W2016092362 hasConceptScore W2016092362C55493867 @default.
- W2016092362 hasConceptScore W2016092362C62746215 @default.
- W2016092362 hasConceptScore W2016092362C8243546 @default.
- W2016092362 hasConceptScore W2016092362C86803240 @default.
- W2016092362 hasConceptScore W2016092362C95444343 @default.
- W2016092362 hasIssue "7" @default.
- W2016092362 hasLocation W20160923621 @default.
- W2016092362 hasLocation W20160923622 @default.
- W2016092362 hasLocation W20160923623 @default.
- W2016092362 hasLocation W20160923624 @default.
- W2016092362 hasOpenAccess W2016092362 @default.
- W2016092362 hasPrimaryLocation W20160923621 @default.
- W2016092362 hasRelatedWork W128713756 @default.
- W2016092362 hasRelatedWork W1975323469 @default.
- W2016092362 hasRelatedWork W1979365145 @default.
- W2016092362 hasRelatedWork W2015152437 @default.
- W2016092362 hasRelatedWork W2044588891 @default.
- W2016092362 hasRelatedWork W2058387931 @default.
- W2016092362 hasRelatedWork W2093696427 @default.
- W2016092362 hasRelatedWork W2416224051 @default.
- W2016092362 hasRelatedWork W30974572 @default.
- W2016092362 hasRelatedWork W3159607164 @default.
- W2016092362 hasVolume "87" @default.
- W2016092362 isParatext "false" @default.
- W2016092362 isRetracted "false" @default.
- W2016092362 magId "2016092362" @default.
- W2016092362 workType "article" @default.