Matches in SemOpenAlex for { <https://semopenalex.org/work/W2016094886> ?p ?o ?g. }
Showing items 1 to 72 of
72
with 100 items per page.
- W2016094886 endingPage "87" @default.
- W2016094886 startingPage "85" @default.
- W2016094886 abstract "In a phase II study of methyl-glyoxal bis-guanylhydrazone (methyl-GAG) in patients with bi-dimensionally measurable metastases of renal cell cancer, 30 patients were given 500 mg/m2 weekly for at least 4 treatment cycles and were evaluable for response. Three patients (10%) achieved partial remission (PR) with a duration of 8-12 weeks; in 11 patients the disease was assessed as stable; and in 16 there was progression. A total of 40 patients were evaluable for toxicity. Nausea and vomiting occurred in 17 (43%), neuropathy, myopathy or myalgia in 8 (21%) and mucositis in 6 (14%). In addition to 3 patients taken off treatment before 4 treatment cycles, toxicity precluded further treatment in 3 others after 5, 6 and 7 cycles respectively. Methyl-GAG has minimal activity in renal cell cancer and, in this dose schedule, causes appreciable toxicity." @default.
- W2016094886 created "2016-06-24" @default.
- W2016094886 creator A5036572342 @default.
- W2016094886 creator A5037696756 @default.
- W2016094886 creator A5055083226 @default.
- W2016094886 creator A5062805582 @default.
- W2016094886 creator A5069222452 @default.
- W2016094886 creator A5084233190 @default.
- W2016094886 date "1982-01-01" @default.
- W2016094886 modified "2023-10-03" @default.
- W2016094886 title "An EORTC phase II study of methyl-glyoxal bis-guanylhydrazone in advanced renal cell cancer" @default.
- W2016094886 cites W1486334137 @default.
- W2016094886 cites W1594985680 @default.
- W2016094886 cites W1986336518 @default.
- W2016094886 cites W2408971276 @default.
- W2016094886 cites W2425159591 @default.
- W2016094886 cites W2608123313 @default.
- W2016094886 doi "https://doi.org/10.1016/0277-5379(82)90030-x" @default.
- W2016094886 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/7200896" @default.
- W2016094886 hasPublicationYear "1982" @default.
- W2016094886 type Work @default.
- W2016094886 sameAs 2016094886 @default.
- W2016094886 citedByCount "8" @default.
- W2016094886 crossrefType "journal-article" @default.
- W2016094886 hasAuthorship W2016094886A5036572342 @default.
- W2016094886 hasAuthorship W2016094886A5037696756 @default.
- W2016094886 hasAuthorship W2016094886A5055083226 @default.
- W2016094886 hasAuthorship W2016094886A5062805582 @default.
- W2016094886 hasAuthorship W2016094886A5069222452 @default.
- W2016094886 hasAuthorship W2016094886A5084233190 @default.
- W2016094886 hasConcept C121608353 @default.
- W2016094886 hasConcept C126322002 @default.
- W2016094886 hasConcept C2778496288 @default.
- W2016094886 hasConcept C2778616394 @default.
- W2016094886 hasConcept C2780580376 @default.
- W2016094886 hasConcept C2780852908 @default.
- W2016094886 hasConcept C29730261 @default.
- W2016094886 hasConcept C31760486 @default.
- W2016094886 hasConcept C71924100 @default.
- W2016094886 hasConcept C90924648 @default.
- W2016094886 hasConceptScore W2016094886C121608353 @default.
- W2016094886 hasConceptScore W2016094886C126322002 @default.
- W2016094886 hasConceptScore W2016094886C2778496288 @default.
- W2016094886 hasConceptScore W2016094886C2778616394 @default.
- W2016094886 hasConceptScore W2016094886C2780580376 @default.
- W2016094886 hasConceptScore W2016094886C2780852908 @default.
- W2016094886 hasConceptScore W2016094886C29730261 @default.
- W2016094886 hasConceptScore W2016094886C31760486 @default.
- W2016094886 hasConceptScore W2016094886C71924100 @default.
- W2016094886 hasConceptScore W2016094886C90924648 @default.
- W2016094886 hasIssue "1" @default.
- W2016094886 hasLocation W20160948861 @default.
- W2016094886 hasLocation W20160948862 @default.
- W2016094886 hasOpenAccess W2016094886 @default.
- W2016094886 hasPrimaryLocation W20160948861 @default.
- W2016094886 hasRelatedWork W1981794048 @default.
- W2016094886 hasRelatedWork W2016094886 @default.
- W2016094886 hasRelatedWork W2031477213 @default.
- W2016094886 hasRelatedWork W2072252734 @default.
- W2016094886 hasRelatedWork W2243375749 @default.
- W2016094886 hasRelatedWork W2328684596 @default.
- W2016094886 hasRelatedWork W2402797049 @default.
- W2016094886 hasRelatedWork W2414579301 @default.
- W2016094886 hasRelatedWork W2472155679 @default.
- W2016094886 hasRelatedWork W2549814790 @default.
- W2016094886 hasVolume "18" @default.
- W2016094886 isParatext "false" @default.
- W2016094886 isRetracted "false" @default.
- W2016094886 magId "2016094886" @default.
- W2016094886 workType "article" @default.